Search Results - "McMaster, W R"

Identification of Synthetic and Natural Host Defense Peptides with Leishmanicidal Activity by Marr, A K, Cen, S, Hancock, R E W, McMaster, W R

“…Leishmaniaparasites are a major public health problem worldwide. Effective treatment of leishmaniasis is hampered by the high incidence of adverse effects to…”
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Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation by Lieke, T, Nylén, S, Eidsmo, L, McMaster, W.R, Mohammadi, A.M, Khamesipour, A, Berg, L, Akuffo, H

“…Natural killer (NK) cells contribute to immunity as the first line of defence in numerous infections by early cytokine secretion and cytotoxicity. In…”
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Expression profiling by whole-genome interspecies microarray hybridization reveals differential gene expression in procyclic promastigotes, lesion-derived amastigotes, and axenic amastigotes in Leishmania mexicana by Holzer, Timothy R., McMaster, W.R., Forney, James D.

“…We examined the Leishmania mexicana transcriptome to identify differentially regulated mRNAs using high-density whole-genome oligonucleotide microarrays…”
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Effective immunization against cutaneous leishmaniasis with recombinant bacille Calmette-Guerin expressing the Leishmania surface proteinase gp63 by Connell, N.D, Medina-Acosta, E, McMaster, W.R, Bloom, B.R, Russell, D.G

“…Leishmania parasites cause a spectrum of diseases that afflict the populations of 86 countries in the world. The parasites can survive within the lysosomal…”
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Cytokine Gene Expression in Healing and Non‐Healing Cases of Cutaneous Leishmaniasis in Response to In vitro Stimulation with Recombinant gp63 Using Semi‐Quantitative RT–PCR by Habibi, G. R., Khamesipour, A., McMaster, W. R., Mahboudi, F.

“…Objectives of this study were to test the cytokine gene expression in peripheral blood mononuclear cells (PBMCs) from cases with nonhealing and healing…”
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Oral Salmonella typhimurium (AroA-) vaccine expressing a major leishmanial surface protein (gp63) preferentially induces T helper 1 cells and protective immunity against leishmaniasis by Yang, DM, Fairweather, N, Button, LL, McMaster, WR, Kahl, LP, Liew, FY

“…The gp63 gene of Leishmania major was transformed into the AroA- vaccine strain of Salmonella typhimurium (SL3261). The construct (SL3261-gp63), which stably…”
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Leishmania mexicana: Identification of Genes That Are Preferentially Expressed in Amastigotes by Bellatin, J.A., Murray, A.S., Zhao, M., McMaster, W.R.

“…Bellatin, J. A., Murray, A. S., Zhao, M., and McMaster, W. R. 2001. Leishmania mexicana: Identification of genes that are preferentially expressed in…”
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Parasite-accessory cell interactions in murine leishmaniasis. II. Leishmania donovani suppresses macrophage expression of Class I and Class II major histocompatibility complex gene products by Reiner, N.E, Ng, W, McMaster, W.R

“…In the present study, we examined the modulation of MHC class II and class I gene products on BALB/c macrophages infected with the obligate intracellular…”
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Survival of Mycobacterium tuberculosis in Host Macrophages Involves Resistance to Apoptosis Dependent upon Induction of Antiapoptotic Bcl-2 Family Member Mcl-1 by Sly, Laura M, Hingley-Wilson, Suzanne M, Reiner, Neil E, McMaster, W. Robert

“…Mcl-1 protein expression was found to be up-regulated during infection with virulent Mycobacterium tuberculosis strain H37Rv. Mcl-1 induction in THP-1 cells…”
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Molecular cloning and expression of a Leishmania major gene encoding a single-stranded DNA-binding protein containing nine "CCHC" zinc finger motifs by WEBB, J. R, MCMASTER, W. R

“…The genes encoding GP63, the major surface glycoprotein of the protozoan parasite Leishmania, are highly conserved across diverse species of Leishmania both…”
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Human T cell responses to gp63, a surface antigen of Leishmania by Russo, DM, Burns, JM, Jr, Carvalho, EM, Armitage, RJ, Grabstein, KH, Button, LL, McMaster, WR, Reed, SG

“…gp63, an abundant and conserved leishmania cell surface protein, has been implicated in the ability of these parasitic protozoa to infect macrophages in vitro…”
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Molecular cloning of the major surface antigen of Leishmania by BUTTON, L. L, MCMASTER, W. R

“…The gene encoding gp63, the major surface glycoprotein of Leishmania promastigotes, was isolated from Leishmania major using a synthetic oligonucleotide probe…”
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Targeted gene deletion in Leishmania major identifies leishmanolysin (GP63) as a virulence factor by Joshi, Phalgun B., Kelly, Ben L., Kamhawi, Shaden, Sacks, David L., McMaster, W.Robert

“…Leishmanolysin, the Leishmania surface metalloproteinase of 63 kDa (GP63) has been described as a parasite virulence factor and is involved in the direct…”
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Inhibition of expression of major histocompatibility complex class II molecules in macrophages infected with Leishmania donovani occurs at the level of gene transcription via a cyclic AMP-independent mechanism by KWAN, W. C, ROBERT MCMASTER, W, WONG, N, REINER, N. E

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Kinetics of γ Interferon Binding and Induction of Major Histocompatibility Complex Class II mRNA in Leishmania-Infected Macrophages by Reiner, Neil E., Ng, Winnie, Ma, Tosca, McMaster, W. Robert

“…Cells of the monocyte-macrophage series must carry out discrete accessory-cell functions during the process of antigen-specific T-cell activation. One of these…”
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Identification of Leishmania genes encoding proteins containing tandemly repeating peptides by WALLIS, A. E, MCMASTER, W. R

“…A genomic Leishmania major DNA expression library was screened using antibodies raised against L. major membranes. Two different clones were identified that…”
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Modification of a recombinant GPI-anchored metalloproteinase for secretion alters the protein glycosylation by Morrison, Charlotte J., Easton, Richard L., Morris, Howard R., McMaster, W. Robert, Piret, James M., Dell, Anne

“…The N‐linked glycans of recombinant leishmanolysin (GP63) expressed as a glycosylphosphatidylinositol (GPI)‐anchored membrane protein or modified for secretion…”
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Heterogeneity of the genes encoding the major surface glycoprotein of Leishmania donovani by Webb, J R, Button, L L, McMaster, W R

“…The major surface glycoprotein of Leishmania (GP63) is present on all known species of Leishmania and likely plays an integral role during the infection of…”
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Antibody Responses of Visceral Leishmaniasis Patients to gp63, a Major Surface Glycoprotein of Leishmania Species by Shrefller, Wayne G., Burns, James M., Badaró, Roberto, Ghalib, Hashim W., Button, Linda L., McMaster, W. Robert, Reed, Steven G.

“…A major surface glycoprotein of Leishmania parasites, gp63, is highly conserved among species and is expressed in both infective and intracellular stages…”
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Role of the Leishmania surface protease gp63 in complement fixation, cell adhesion, and resistance to complement-mediated lysis by Brittingham, A, Morrison, CJ, McMaster, WR, McGwire, BS, Chang, KP, Mosser, DM

“…The Leishmania surface protease gp63 has been identified as a parasite virulence factor. To better define the role of gp63 in Leishmania infectivity, the…”
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