Search Results - "McMaster, Robert"

The Work of Community Gardens: Reclaiming Place for Community in the City by Cumbers, Andrew, Shaw, Deirdre, Crossan, John, McMaster, Robert

“…The growth of community gardens has become the source of much academic debate regarding their role in community empowerment in the contemporary city. In this…”
Get full text

Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63 by Contreras, Irazú, Gómez, María Adelaida, Nguyen, Oliver, Shio, Marina T, McMaster, Robert W, Olivier, Martin

“…Leishmania parasites have evolved sophisticated mechanisms to subvert macrophage immune responses by altering the host cell signal transduction machinery,…”
Get full text

Association of Serum MiR-142-3p and MiR-101-3p Levels with Acute Cellular Rejection after Heart Transplantation by Sukma Dewi, Ihdina, Hollander, Zsuzsanna, Lam, Karen K, McManus, Janet-Wilson, Tebbutt, Scott J, Ng, Raymond T, Keown, Paul A, McMaster, Robert W, McManus, Bruce M, Gidlöf, Olof, Öhman, Jenny

“…Identifying non-invasive and reliable blood-derived biomarkers for early detection of acute cellular rejection in heart transplant recipients is of great…”
Get full text

Leishmania donovani infection causes distinct epigenetic DNA methylation changes in host macrophages by Marr, Alexandra K, MacIsaac, Julia L, Jiang, Ruiwei, Airo, Adriana M, Kobor, Michael S, McMaster, W Robert

“…Infection of macrophages by the intracellular protozoan Leishmania leads to down-regulation of a number of macrophage innate host defense mechanisms, thereby…”
Get full text

Secreted virulence factors and immune evasion in visceral leishmaniasis by Lambertz, Ulrike, Silverman, Judith Maxwell, Nandan, Devki, McMaster, W. Robert, Clos, Joachim, Foster, Leonard J., Reiner, Neil E.

“…Review of leishmania secreted virulence factors and their immune‐modulatory functions, as well as exosome release as a major mechanism for effector secretion…”
Get full text

Leishmania donovani promastigotes evade the antimicrobial activity of neutrophil extracellular traps by Gabriel, Christelle, McMaster, W Robert, Girard, Denis, Descoteaux, Albert

“…Upon their recruitment to a site of infection and their subsequent activation, neutrophils release DNA and a subset of their granule content to form…”
Get full text

Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection by Jaramillo, Maritza, Gomez, Maria Adelaida, Larsson, Ola, Shio, Marina Tiemi, Topisirovic, Ivan, Contreras, Irazú, Luxenburg, Randi, Rosenfeld, Amy, Colina, Rodney, McMaster, Robert W, Olivier, Martin, Costa-Mattioli, Mauro, Sonenberg, Nahum

“…The protozoan parasite Leishmania alters the activity of its host cell, the macrophage. However, little is known about the effect of Leishmania infection on…”
Get full text

Exosomal miR-142-3p is increased during cardiac allograft rejection and augments vascular permeability through down-regulation of endothelial RAB11FIP2 expression by Sukma Dewi, Ihdina, Celik, Selvi, Karlsson, Anna, Hollander, Zsuzsanna, Lam, Karen, McManus, Janet-Wilson, Tebbutt, Scott, Ng, Raymond, Keown, Paul, McMaster, Robert, McManus, Bruce, Öhman, Jenny, Gidlöf, Olof

“…Exosome-mediated microRNA transfer is a recently discovered mode of cell-to-cell communication, in which microRNAs act as paracrine molecules, exerting their…”
Get full text

Leishmania exosomes modulate innate and adaptive immune responses through effects on monocytes and dendritic cells by Silverman, Judith Maxwell, Clos, Joachim, Horakova, Eva, Wang, Adele Y, Wiesgigl, Martina, Kelly, Isabelle, Lynn, Miriam A, McMaster, W Robert, Foster, Leonard J, Levings, Megan K, Reiner, Neil E

“…We investigated the properties of leishmania exosomes with respect to influencing innate and adaptive immune responses. Exosomes from Leishmania donovani…”
Get full text

GIS diffusion in Uganda by Eria, Sami, McMaster, Robert B.

“…Despite myriad studies having been carried out on the diffusion of geographical information systems (GIS) technology, only a limited number have been done…”
Get full text

Evolution in Economic Geography: Institutions, Political Economy, and Adaptation by MacKinnon, Danny, Cumbers, Andrew, Pike, Andy, Birch, Kean, McMaster, Robert

“…Economic geography has, over the past decade or so, drawn upon ideas from evolutionary economics in trying to understand processes of regional growth and…”
Get full text

Leishmania GP63 alters host signaling through cleavage-activated protein tyrosine phosphatases by Gomez, Maria Adelaida, Contreras, Irazu, Hallé, Maxime, Tremblay, Michel L, McMaster, Robert W, Olivier, Martin

“…With more than 12 million people affected worldwide, 2 million new cases occurring per year, and the rapid emergence of drug resistance and treatment failure,…”
Get more information

Cysteine Peptidase B Regulates Leishmania mexicana Virulence through the Modulation of GP63 Expression by Casgrain, Pierre-André, Martel, Caroline, McMaster, W Robert, Mottram, Jeremy C, Olivier, Martin, Descoteaux, Albert

“…Cysteine peptidases play a central role in the biology of Leishmania. In this work, we sought to further elucidate the mechanism(s) by which the cysteine…”
Get full text

Impact of Leishmania infection on host macrophage nuclear physiology and nucleopore complex integrity by Isnard, Amandine, Christian, Jan G, Kodiha, Mohamed, Stochaj, Ursula, McMaster, W Robert, Olivier, Martin

“…The protease GP63 is an important virulence factor of Leishmania parasites. We previously showed that GP63 reaches the perinuclear area of host macrophages and…”
Get full text

Population health post-pandemic: critiquing the economic approach to recovery by Shipton, Debs, McCartney, Gerry, McMaster, Robert

“…The COVID-19 pandemic has exposed that the economic crisis is inseparable from the health and inequalities crisis. This commentary identifies the key…”
Get full text

The Leishmania Surface Protease GP63 Cleaves Multiple Intracellular Proteins and Actively Participates in p38 Mitogen-activated Protein Kinase Inactivation by Hallé, Maxime, Gomez, Maria Adelaida, Stuible, Matthew, Shimizu, Hidehisa, McMaster, W.Robert, Olivier, Martin, Tremblay, Michel L.

“…The Leishmania parasite is a widespread disease threat in tropical areas, causing symptoms ranging from skin lesions to death. Leishmania parasites typically…”
Get full text

Effect of BMAP-28 antimicrobial peptides on Leishmania major promastigote and amastigote growth: role of leishmanolysin in parasite survival by Lynn, Miriam A, Kindrachuk, Jason, Marr, Alexandra K, Jenssen, Håvard, Panté, Nelly, Elliott, Melissa R, Napper, Scott, Hancock, Robert E, McMaster, W Robert

“…Protozoan parasites, such as Leishmania, still pose an enormous public health problem in many countries throughout the world. Current measures are outdated and…”
Get full text

Modes of action of Leishmanicidal antimicrobial peptides by Marr, Alexandra K, McGwire, Bradford S, McMaster, W Robert

“…Leishmaniasis is one of the major neglected tropical diseases of the world. It is present in 88 countries with an estimated number of 500,000 cases of visceral…”
Get more information

Adaptation of the Clinical Global Impression for Use in Correctional Settings: The CGI-C by Jones, Roland M, Patel, Kiran, Moscovici, Mario, McMaster, Robert, Glancy, Graham, Simpson, Alexander I.F.

“…Background: Provision of mental health care in correctional settings presents unique challenges. There is a need for a simple-to-use tool to measure severity…”
Get full text

Plasma protein biosignatures for detection of cardiac allograft vasculopathy by Lin, David, PhD, Cohen Freue, Gabriela, PhD, Hollander, Zsuzsanna, PhD, John Mancini, G.B., MD, FRCPC, Sasaki, Mayu, MPH, Mui, Alice, PhD, Wilson-McManus, Janet, BS, MT(ASCP), Ignaszewski, Andrew, MD, FRCPC, Imai, Carol, BSN, Meredith, Anna, BS, Balshaw, Robert, PhD, Ng, Raymond T., PhD, Keown, Paul A., MD, DS, Robert McMaster, W., PhD, Carere, Ron, MD, FRCPC, Webb, John G., MD, FRCPC, McManus, Bruce M., MD, PhD

“…Background Coronary angiography remains the most widely used tool for routine screening and diagnosis of cardiac allograft vasculopathy (CAV), a major…”
Get full text