Search Results - "McMartin, K.E."

Mechanistic studies on diethylene glycol poisoning to develop new therapies? by McMartin, K.E., Robinson, C., Conrad, T., Landry, G.

Get full text

Extension of a PBPK model for ethylene glycol and glycolic acid to include the competitive formation and clearance of metabolites associated with kidney toxicity in rats and humans by Corley, R.A., Saghir, S.A., Bartels, M.J., Hansen, S.C., Creim, J., McMartin, K.E., Snellings, W.M.

“…A previously developed PBPK model for ethylene glycol and glycolic acid was extended to include glyoxylic acid, oxalic acid, and the precipitation of calcium…”
Get full text

Dosimetry considerations in the enhanced sensitivity of male Wistar rats to chronic ethylene glycol-induced nephrotoxicity by Corley, R.A., Wilson, D.M., Hard, G.C., Stebbins, K.E., Bartels, M.J., Soelberg, J.J., Dryzga, M.D., Gingell, R., McMartin, K.E., Snellings, W.M.

“…Male Wistar rats have been shown to be the most sensitive sex, strain and species to ethylene glycol-induced nephrotoxicity in subchronic studies. A chronic…”
Get full text

The role of calcium oxalate crystal deposition in cerebral vessels during ethylene glycol poisoning by Froberg, K, Dorion, R P, McMartin, K E

“…Ethylene glycol (EG) poisoning can lead to serious morbidity or death, which occurs following conversion of ethylene glycol to toxic metabolites. These…”
Get full text

In vitro characterization of renal reabsorption and secretion of folate using primary cultures of human kidney cells by Morshed, Khandoker M., McMartin, Kenneth E.

“…Proximal tubule cells in the kidney play an important role in the homeostasis of folate. Mechanistic studies on folate reabsorption and secretion across the…”
Get full text

Effects of chronic ethanol and diet treatment on urinary folate excretion and development of folate deficiency in the rat by McMartin, K E, Collins, T D, Eisenga, B H, Fortney, T, Bates, W R, Bairnsfather, L

“…Because the folate deficiency of chronic alcoholism has been proposed to result from ethanol-induced effects on metabolism or urinary excretion of folate, the…”
Get more information

The Role of Calcium Oxalate Crystal Deposition in Cerebral Vessels During Ethylene Glycol Poisoning by Froberg, K., Dorion, R.P., McMartin, K.E.

“…Ethylene glycol (EG) poisoning can lead to serious morbidity or death, which occurs following conversion of ethylene glycol to toxic metabolites. These…”
Get full text

High-pressure liquid chromatography separation and determination of rat liver folates by McMartin, K E, Virayotha, V, Tephly, T R

Get more information

Effects of acute ethanol on urinary excretion of 5-methyltetrahydrofolic acid and folate derivatives in the rat by Eisenga, B H, Collins, T D, McMartin, K E

“…Acute ethanol treatment enhances the urinary excretion of endogenous folate. This effect has been implicated in the development of folate deficiency associated…”
Get more information

Deficiencia de folato y concentraciones elevadas de formato en suero y líquido cefalorraquídeo de pacientes con neuropatía óptica epidémica by Eells, J.T, González-Quevedo, Alina, Santiesteban Freixas, Rosaralis, McMartin, K.E., Sadun, A.A.

“…Se estudiaron 62 pacientes con neuropatía óptica bilateral, diagnosticados durante una epidemia en la provincia Pinar del Río, con una edad media de 48 años…”
Get full text

Methanol poisoning: ocular toxicity produced by formate by Martin-Amat, G, McMartin, K E, Hayreh, S S, Hayreh, M S, Tephly, T R

Get more information

Incorporation of 3H-label from folic acid is tissue-dependent in folate-deficient rats by Eisenga, B H, Collins, T D, McMartin, K E

“…To study the tissue-specificity of folate deficiency, male Sprague-Dawley rats were fed folate-replete or folate-deficient diets with and without sulfonamide…”
Get more information

Methanol poisoning. I. The role of formic acid in the development of metabolic acidosis in the monkey and the reversal by 4-methylpyrazole by McMartin, K E, Makar, A B, Martin, G, Palese, M, Tephly, T R

Get more information

Formate assay in body fluids: application in methanol poisoning by Makar, A B, McMartin, K E, Palese, M, Tephly, T R

Get more information