Search Results - "McManus, D Q"

Autosomal dominant Kufs' disease: a cause of early onset dementia by Josephson, S.A., Schmidt, R.E., Millsap, P., McManus, D.Q., Morris, J.C.

“…Kufs' disease is the rare, adult-onset form of the neuronal ceroid-lipofuscinoses (NCL). Two clinical Kufs' phenotypes have been described, one featuring…”
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Evidence for association of HLA-A2 allele with onset age of Alzheimer's disease by PAYAMI, H, SCHELLENBERG, G. D, BIRD, T. D, KATZMAN, R, HESTON, L, NORMAN, D, SMALL, G. W, ZAREPARSI, S, KAYE, J, SEXTON, G. J, HEAD, M. A, MATSUYAMA, S. S, JARVIK, L. F, MILLER, B, MCMANUS, D. Q

“…Our earlier studies had suggested a possible association between the HLA-A2 allele and Alzheimer's disease (AD). In the present study we tested the hypothesis…”
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Age- and concentration-dependent neuroprotection and toxicity by TNF in cortical neurons from β-amyloid by Viel, J.J., McManus, D.Q., Smith, Sherry S., Brewer, G.J.

“…The induction of an inflammatory response and release of cytokines such as TNF may be involved in the age‐related etiology of Alzheimer disease (AD). In the…”
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Quetiapine, a novel antipsychotic : Experience in elderly patients with psychotic disorders by MCMANUS, D. Q, ARVANITIS, L. A, KOWALCYK, B. B

“…BACKGROUND: This uncontrolled trial examines the safety and effects of quetiapine, a new atypical antipsychotic, in elderly patients with psychotic disorders…”
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Culture of neurons from postmortem rat brain by McManus, Dennis Q, Brewer, Gregory J

“…Live neurons from pathological postmortem brains may provide a better model to study the molecular and cellular events associated with neurodegenerative…”
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Postmortem effect of pentobarbital anesthetic on survival of adult cortical neurons in primary culture by Viel, John J., McManus, Dennis Q., Brewer, Gregory J.

“…We determined whether pentobarbital anesthetic is required to culture postmortem adult rat neurons. Pentobarbital treatment resulted in two-fold increases in…”
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Temperature and time interval for culture of postmortem neurons from adult rat cortex by Viel, John J., McManus, Dennis Q., Cady, Craig, Evans, M. Steven, Brewer, Gregory J.

“…For a model of neurological disease and ischemia, we extended recent work to culture adult postmortem rat brain neurons. Frontal cortex sections were removed…”
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Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: neurochemical effects in the spinal cord by Virus, R M, McManus, D Q, Gebhart, G F

“…The effects of s.c. capsaicin treatment on the thoracic spinal cord contents of immunoreactive substance P (ISP), norepinephrine (NE) and serotonin (5-HT) were…”
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Carbamazepine metabolism in humans: effect of concurrent anticonvulsant therapy by Ramsay, R E, McManus, D Q, Guterman, A, Briggle, T V, Vazquez, D, Perchalski, R, Yost, R A, Wong, P

“…Free and total carbamazepine (CBZ) and carbamazepine-epoxide (CBZ-EP) plasma levels were obtained on 113 patients with epilepsy (18-61 years old) controlled on…”
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Lesions in nucleus reticularis gigantocellularis: effect on the antinociception produced by micro-injection of morphine and focal electrical stimulation in the periaqueductal gray matter by Mohrland, J S, McManus, D Q, Gebhart, G F

“…The effect of bilateral electrolytic lesions in the nucleus reticularis giganto-cellularis (NGC) on the antinociceptive efficacy of morphine and electrical…”
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Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: effects on nociceptive behavior and cardiovascular regulation by Virus, R M, Knuepfer, M M, McManus, D Q, Brody, M J, Gebhart, G F

“…Effects of s.c. capsaicin pretreatment on nociception, mean systemic arterial blood pressure, and dose-response curves for depressor effects of substance P…”
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Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: effects on substance P contents of peripheral and central nervous system tissues by Virus, R M, McManus, D Q, Gebhart, G F

“…The effects of s.c. capsaicin treatment on the contents of immunoreactive substance P (ISP) in several peripheral and central nervous system tissues were…”
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Quetiapine, a novel antipsychotic: experience in elderly patients with psychotic disorders. Seroquel Trial 48 Study Group by McManus, D Q, Arvanitis, L A, Kowalcyk, B B

“…This uncontrolled trial examines the safety and effects of quetiapine, a new atypical antipsychotic, in elderly patients with psychotic disorders. This is an…”
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The neurology of aging: normal versus pathologic change by Morris, J C, McManus, D Q

“…Mild changes in neurologic function occur with aging but generally do not substantially interfere with everyday activities unless disease intervenes. Not…”
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