Search Results - "McManus, Ciara A."

Plasma N-glycans in colorectal cancer risk by Doherty, Margaret, Theodoratou, Evropi, Walsh, Ian, Adamczyk, Barbara, Stöckmann, Henning, Agakov, Felix, Timofeeva, Maria, Trbojević-Akmačić, Irena, Vučković, Frano, Duffy, Fergal, McManus, Ciara A., Farrington, Susan M., Dunlop, Malcolm G., Perola, Markus, Lauc, Gordan, Campbell, Harry, Rudd, Pauline M.

“…Aberrant glycosylation has been associated with a number of diseases including cancer. Our aim was to elucidate changes in whole plasma N -glycosylation…”
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Glycan characterization of the NIST RM monoclonal antibody using a total analytical solution: From sample preparation to data analysis by Hilliard, Mark, Alley, Jr, William R, McManus, Ciara A, Yu, Ying Qing, Hallinan, Sinead, Gebler, John, Rudd, Pauline M

“…Glycosylation is an important attribute of biopharmaceutical products to monitor from development through production. However, glycosylation analysis has…”
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High-throughput quantitative N-glycan analysis of glycoproteins by Doherty, Margaret, McManus, Ciara A, Duke, Rebecca, Rudd, Pauline M

“…N-linked oligosaccharides are complex non-template-derived structures that are attached to the side chains of asparagine, via the nitrogen atom. Specific…”
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Effect of phosphorylated hsp27 on proliferation of human endothelial and smooth muscle cells by Trott, Deborah, McManus, Ciara A, Martin, Jody L, Brennan, Bryony, Dunn, Michael J, Rose, Marlene L

“…Recent studies have suggested a protective role of hsp27 against atherosclerosis and transplant graft vasculopathy. Here we have investigated the effects of…”
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A fluorescent codetection system for immunoblotting and proteomics through ECL-Plex and CyDye labeling by McManus, Ciara A, Donoghue, Pamela M, Dunn, Michael J

“…The qualitative and quantitative capabilities of 2-D electrophoresis and its use in widespread proteome analysis has been revolutionized over the past decade…”
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IgG Fc glycosylation as an axis of humoral immunity in childhood by Cheng, Hao D., Tirosh, Irit, de Haan, Noortje, Stöckmann, Henning, Adamczyk, Barbara, McManus, Ciara A., O’Flaherty, Róisín, Greville, Gordon, Saldova, Radka, Bonilla, Francisco A., Notarangelo, Luigi D., Driessen, Gertjan J., Holm, Ingrid A., Rudd, Pauline M., Wuhrer, Manfred, Ackerman, Margaret E., Nigrovic, Peter A.

“…IgG Fc glycans were characterized in 225 healthy children and 40 children with unexplained recurrent respiratory infections, revealing age-dependent variation…”
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High-throughput characterization of the functional impact of IgG Fc glycan aberrancy in juvenile idiopathic arthritis by Cheng, Hao D, Stöckmann, Henning, Adamczyk, Barbara, McManus, Ciara A, Ercan, Altan, Holm, Ingrid A, Rudd, Pauline M, Ackerman, Margaret E, Nigrovic, Peter A

“…Juvenile idiopathic arthritis (JIA) encompasses all forms of chronic idiopathic arthritis that arise before age 16. Previous studies have found JIA to be…”
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A novel role for the fibrinogen Asn-Gly-Arg (NGR) motif in platelet function by Moriarty, Róisín, McManus, Ciara A, Lambert, Matthew, Tilley, Thea, Devocelle, Marc, Brennan, Marian, Kerrigan, Steven W, Cox, Dermot

“…The integrin αIIbβ3 on resting platelets can bind to immobilised fibrinogen resulting in platelet spreading and activation but requires activation to bind to…”
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Co-detection of Target and Total Protein by CyDye Labeling and Fluorescent ECL Plex Immunoblotting in a Standard Proteomics Workflow by Scaife, Caitriona, McManus, Ciara A, Donoghue, Pamela M, Dunn, Michael J

“…The qualitative and quantitative capabilities of 2-D electrophoresis and its use in widespread proteome analysis have been revolutionized over the past decade…”
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A 2-D gel reference map of the basic human heart proteome by Polden, Julie, McManus, Ciara A., Dos Remedios, Cris, Dunn, Michael J.

“…We have undertaken the identification of basic proteins (pH 6–11) of the human heart using 2‐DE. Tissue from the left ventricle of human heart was lysed and…”
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Inward rectifier potassium conductance regulates membrane potential of canine colonic smooth muscle by Flynn, Elaine R. M., McManus, Ciara A., Bradley, Karri K., Koh, Sang Don, Hegarty, Terry M., Horowitz, Burton, Sanders, Kenton M.

“…The membrane potential of gastrointestinal smooth muscles determines the open probability of ion channels involved in rhythmic electrical activity. The role of…”
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Two-dimensional reference map for the basic proteome of the human dorsolateral prefrontal cortex (dlPFC) of the prefrontal lobe region of the brain by McManus, Ciara A, Polden, Julie, Cotter, David R, Dunn, Michael J

“…We describe a 2-DE proteomic reference map containing 227 basic proteins in the dorsolateral prefrontal cortex region of the human brain. Proteins were…”
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1st Irish Proteomics Workshop April 17th 2008, University College Dublin, Conway Institute, Dublin, Ireland by McManus, Ciara A, English, Jane A

“…The workshop assembled an excellent collection of speakers from across Ireland and beyond who presented many interesting and diverse topical issues. Various…”
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From Genome to Proteome: Back to the Future Report on the 7th Siena meeting, September 3-7, 2006 by Pennington, Kyla, Pedersen, Kasper J., McManus, Ciara A.

“…This report reviews the 7th Siena Meeting ‘From Genome to Proteome: Back to the Future’ which took place in Italy from 3–7 September, 2006. There was a…”
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CyDye Immunoblotting for Proteomics: Co-detection of specific immunoreactive and total protein profiles by Donoghue, Pamela M., McManus, Ciara A., O'Donoghue, Niaobh M., Pennington, Stephen R., Dunn, Michael J.

“…The development of ECL‐Plex CyDye‐conjugated secondary antibodies allows the advancement of conventional Western blotting, opening up possibilities for highly…”
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1 st Irish Proteomics Workshop April 17 th 2008, University College Dublin, Conway Institute, Dublin, Ireland by McManus, Ciara A., English, Jane A.

“…Abstract The workshop assembled an excellent collection of speakers from across Ireland and beyond who presented many interesting and diverse topical issues…”
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From Genome to Proteome: Back to the Future Report on the 7 th Siena meeting, September 3–7, 2006 by Pennington, Kyla, Pedersen, Kasper J., McManus, Ciara A.

“…Abstract This report reviews the 7 th Siena Meeting ‘From Genome to Proteome: Back to the Future’ which took place in Italy from 3–7 September, 2006. There was…”
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Proteomics of transplant rejection by McManus, Ciara A., Rose, Marlene L., Dunn, Michael J.

“…Although the number of patients receiving successful transplantation as a means of treatment for end-stage organ failure continues to increase, rejection, in…”
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Glycan characterization of the NIST RM monoclonal antibody using a total analytical solution: From sample preparation to data analysis by Hilliard, Mark, Alley, William R., McManus, Ciara A., Yu, Ying Qing, Hallinan, Sinead, Gebler, John, Rudd, Pauline M.

“…Glycosylation is an important attribute of biopharmaceutical products to monitor from development through production. However, glycosylation analysis has…”
Get full text