Search Results - "McMahon, Gilbert"

Dose-Related Inflammatory Effects of Intravenous Endotoxin in Humans: Evaluation of a New Clinical Lot of Escherichia coli O:113 Endotoxin by Suffredini, Anthony F., Hochstein, H. Donald, McMahon, F. Gilbert

“…The administration of reference endotoxin (Escherichia coli O:113, Lot EC-5) to humans has been an important means to study inflammation in vivo; however, the…”
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Blocking of Responses to Endotoxin by E5564 in Healthy Volunteers with Experimental Endotoxemia by Lynn, Melvyn, Rossignol, Daniel P, Wheeler, Janice L, Kao, Richard J, Perdomo, Carlos A, Noveck, Robert, Vargas, Ramon, D’Angelo, Tony, Gotzkowsky, Sandra, McMahon, F. Gilbert

“…E5564 is a second-generation synthetic analogue of the lipid A component of endotoxin (lipopolysaccharide [LPS]). The ability of E5564 to block the toxic…”
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Extended in vivo pharmacodynamic activity of E5564 in normal volunteers with experimental endotoxemia [corrected] by Lynn, Melvyn, Wong, Y Nancy, Wheeler, Janice L, Kao, Richard J, Perdomo, Carlos A, Noveck, Robert, Vargas, Ramon, D'Angelo, Tony, Gotzkowsky, Sandra, McMahon, F Gilbert, Wasan, Kishor M, Rossignol, Daniel P

“…E5564 (alpha-D-glucopyranose) is a synthetic antagonist of bacterial endotoxin that has been shown to completely block human endotoxin response. Low doses of…”
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Effects of an ACE inhibitor/calcium antagonist combination on proteinuria in diabetic nephropathy by Bakris, George L., Weir, Matthew R., Dequattro, Vincent, McMahon, F. Gilbert

“…Effects of an ACE inhibitor/calcium antagonist combination on proteinuria in diabetic nephropathy. The degree of proteinuria in patients with diabetes…”
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Sibutramine is safe and effective for weight loss in obese patients whose hypertension is well controlled with angiotensin-converting enzyme inhibitors by McMahon, F G, Weinstein, S P, Rowe, E, Ernst, K R, Johnson, F, Fujioka, K

“…Sibutramine treatment in obesity results in significantly greater weight reduction compared with placebo, although weight loss with sibutramine may be…”
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Can garlic reduce levels of serum lipids? A controlled clinical study by Jain, A K, Vargas, R, Gotzkowsky, S, McMahon, F G

“…To assess the effects of standardized garlic powder tablets on serum lipids and lipoproteins, glucose, and blood pressure. Forty-two healthy adults (19 men, 23…”
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A new clinical bioassay for antipyresis by McMahon, F G, Vargas, R

“…Three studies that describe antipyretic bioassay are detailed. Reference Standard Endotoxin (RSE) was used to induce fever in healthy male volunteers under…”
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Clonidine-chlorthalidone combination once and twice daily in essential hypertension by Noveck, R J, McMahon, F G, Jain, A K, Ryan, J R

“…The antihypertensive effects of a clonidine-chlorthalidone combination (Combipres) as a single daily dose at bedtime and the same amount in twice-daily doses…”
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Pretreatment of normal humans with monophosphoryl lipid A induces tolerance to endotoxin: A prospective, double-blind, randomized, controlled trial by Astiz, Mark E, Rackow, Eric C, Still, J. Gordon, Howell, Scott T, Cato, Allen, B. Von Eschen, Kenneth, Ulrich, J. Terry, Rudbach, Jon A, McMahon, Gilbert, Vargas, Ramon, Stern, Warren

“…OBJECTIVESEndotoxin is one of the principal mediators of Gram-negative septic shock. Pretreatment with monophosphoryl lipid A, a hydrolyzed derivative of…”
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Hypertension in Hypoglycemic Diabetics Treated with β-Adrenergic Antagonists by RYAN, JEROME R, LACORTE, WILLIAM, JAIN, ADESH, MCMAHON, F GILBERT

“…To evaluate the response during insulin-induced hypoglycemia, diabetics treated with relatively selective or nonselective β-adrenergic blocking agents were…”
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A double-blind study of diflunisal and codeine compared with codeine or diflunisal alone in postoperative pain by Jain, A, McMahon, F G, Ryan, J R, Smith, G, Berman, R

“…A double-blind, randomized, parallel-group study compared the analgesic efficacy of a single oral dose of 500 mg diflunisal, 60 mg codeine, 500 mg diflunisal…”
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Long-term safety and efficacy of oral phentolamine mesylate (Vasomax®) in men with mild to moderate erectile dysfunction by PADMA-NATHAN, H, GOLDSTEIN, I, KLIMBERG, I, COOGAN, C, AUERBACH, S, LAMMERS, P

“…The objectives of this study were to evaluate long-term safety and efficacy of phentolamine mesylate, an orally active, rapid-acting alpha-adrenergic receptor…”
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Dose proportionality of amrinone by Edelson, J, Park, G B, Angellotti, J, Kershner, R P, Ryan, J J, McMahon, F G

“…Amrinone was given to 18 healthy subjects in doses of 75, 150, and 225 mg in a randomized crossover design. Plasma levels were shown to rise in proportion to…”
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Effect of naproxen on the steady-state serum concentration and anticoagulant activity of warfarin by Jain, A, McMahon, F G, Slattery, J T, Levy, G

“…The purpose of this investigation was to determine whether the anti-inflammatory drug naproxen interacts with warfarin during prolonged administration of both…”
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Efficacy and acceptability of different dosage schedules of clonidine by Jain, A K, Ryan, J R, Vargas, R, McMahon, F G

“…In 12 hospitalized patients with hypertension, clonidine 3 times a day led to better control of blood pressure than did the same total dose administered once…”
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Does your institutional review board review advertising for recruits? by McMahon, F G

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Guanabenz in essential hypertension by McMahon, F G, Ryan, J R, Jain, A K, Vargas, R, Vanov, S K

“…Fifty-five patients with mild to moderately severe essential hypertension were treated with guanabenz (2, 6-dichlorobenzylidene aminoguanidine acetate) in…”
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Panel III. Intervention: the use of drug utilization review outcomes

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Sibutramine is safe and effective for weight loss in obese patients whose hypertension is well controlled with angiotensin-converting enzyme inhibitors by McMahon, F G, Weinstein, S P, Rowe, E, Ernst, K R, Johnson, F, Fujioka, K

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Long-term treatment of hypercholesterolemia with colestipol hydrochloride by Ryan, J R, Jain, A K, McMahon, F G

“…Colestipol hydroxhloride (15 gm/day) (an anion exchange resin that binds bile acids) of placebo was administered to 92 patients with hypercholesterolemia who…”
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