Search Results - "McMahan, Sara"
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Heart valve tissue‐derived hydrogels: Preparation and characterization of mitral valve chordae, aortic valve, and mitral valve gels
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-07-2019)“…Heart valve (HV) diseases are among the leading causes of death and continue to threaten public health worldwide. The current clinical options for HV…”
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Epicardial prestrained confinement and residual stresses: a newly observed heart ventricle confinement interface
Published in Journal of the Royal Society interface (01-03-2019)“…The heart epicardial layer, with elastin as the dominant component, has not been well investigated, specifically on how it contributes to ventricular…”
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Using models to advance medicine: mathematical modeling of post-myocardial infarction left ventricular remodeling
Published in Computer methods in biomechanics and biomedical engineering (17-02-2022)“…The heart is an organ with limited capacity for regeneration and repair. The irreversible cell death and corresponding diminished ability of the heart to…”
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Spatial distribution and network morphology of epicardial, endocardial, interstitial, and Purkinje cell-associated elastin fibers in porcine left ventricle
Published in Bioactive materials (01-01-2023)“…Cardiac extracellular matrices (ECM) play crucial functional roles in cardiac biomechanics. Previous studies have mainly focused on collagen, the major…”
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Investigating the Transient Regenerative Potential of Cardiac Muscle Using a Neonatal Pig Partial Apical Resection Model
Published in Bioengineering (Basel) (01-08-2022)“…Researchers have shown that adult zebrafish have the potential to regenerate 20% of the ventricular muscle within two months of apex resection, and neonatal…”
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Current advances in biodegradable synthetic polymer based cardiac patches
Published in Journal of biomedical materials research. Part A (01-04-2020)“…The number of people affected by heart disease such as coronary artery disease and myocardial infarction increases at an alarming rate each year. Currently,…”
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An in vitro system to investigate IOL: Lens capsule interaction
Published in Experimental eye research (01-02-2021)“…Posterior capsule opacification (PCO) is the most common complication associated with intraocular lens (IOL) implantation. Unfortunately, current in vitro…”
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In vitro comparison of harvesting site effects on cardiac extracellular matrix hydrogels
Published in Journal of biomedical materials research. Part A (01-10-2021)“…Cardiac extracellular matrix (cECM) derived hydrogel has been investigated to treat myocardial infarction through animal studies and clinical trials. The…”
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Abstract 373: Impacts of Harvesting Sites on Cardiac Extracellular Matrix Hydrogels Properties
Published in Circulation research (31-07-2020)“…Abstract only Introduction: Cardiac extracellular matrix (cECM) hydrogel has been explored to treat myocardial infarction (MI). It possesses organ specific…”
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Abstract 840: Epicardial Prestrained Confinement and Residual Stresses: A Newly Observed Heart Ventricle Confinement Interface
Published in Circulation research (02-08-2019)“…Abstract only The heart epicardial layer, with elastin as the dominant component, has not been well investigated, specifically on how it contributes to…”
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Reduced Graphene-Oxide-Doped Elastic Biodegradable Polyurethane Fibers for Cardiomyocyte Maturation
Published in ACS biomaterials science & engineering (10-06-2024)“…Conductive biomaterials offer promising solutions to enhance the maturity of cultured cardiomyocytes. While the conventional culture of cardiomyocytes on…”
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The Biomechanics of Cardiac Elastin and Its Role in Bioengineering
Published 01-01-2020“…Elastin is an essential structural protein responsible for the elasticity of many tissues, including skin, lungs, blood vessels, and other highly dynamic…”
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Dissertation