Search Results - "McMahan, Ryan S"

Stromelysin-2 (MMP10) Moderates Inflammation by Controlling Macrophage Activation by McMahan, Ryan S, Birkland, Timothy P, Smigiel, Kate S, Vandivort, Tyler C, Rohani, Maryam G, Manicone, Anne M, McGuire, John K, Gharib, Sina A, Parks, William C

“…Several members of the matrix metalloproteinase (MMP) family control a range of immune processes, such as leukocyte influx and chemokine activity…”
Get full text

Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3 by Riehle, Kimberly J, Campbell, Jean S, McMahan, Ryan S, Johnson, Melissa M, Beyer, Richard P, Bammler, Theo K, Fausto, Nelson

“…Suppressor of cytokine signaling 3 (SOCS3) down-regulates several signaling pathways in multiple cell types, and previous data suggest that SOCS3 may shut off…”
Get full text

Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice by Haque, Jamil A, McMahan, Ryan S, Campbell, Jean S, Shimizu-Albergine, Masami, Wilson, Angela M, Botta, Dianne, Bammler, Theo K, Beyer, Richard P, Montine, Thomas J, Yeh, Matthew M, Kavanagh, Terrance J, Fausto, Nelson

“…In nonalcoholic fatty liver disease (NAFLD), depletion of hepatic antioxidants may contribute to the progression of steatosis to nonalcoholic steatohepatitis…”
Get full text

Relationships between Deficits in Tissue Mass and Transcriptional Programs after Partial Hepatectomy in Mice by Li, Jiangning, Campbell, Jean S, Mitchell, Claudia, McMahan, Ryan S, Yu, Xuesong, Riehle, Kimberly J, Bumgarner, Roger E, Fausto, Nelson

“…Liver regeneration after two-thirds partial hepatectomy (2/3 PH) results in synchronized proliferation of hepatocytes and rapid restoration of liver mass…”
Get full text

Transcriptional and functional diversity of human macrophage repolarization by Gharib, Sina A., McMahan, Ryan S., Eddy, William E., Long, Matthew E., Parks, William C., Aitken, Moira L., Manicone, Anne M.

“…Macrophage plasticity allows cells to adopt different phenotypes, a property with important implications in disorders such as cystic fibrosis (CF) and asthma…”
Get full text

MMP-10 Regulates Collagenolytic Activity of Alternatively Activated Resident Macrophages by Rohani, Maryam G., McMahan, Ryan S., Razumova, Maria V., Hertz, Angie L., Cieslewicz, Maryelise, Pun, Suzie H., Regnier, Michael, Wang, Ying, Birkland, Timothy P., Parks, William C.

“…Matrix metalloproteinase-10 (MMP-10) is expressed by macrophages and epithelium in response to injury, but its functions in wound repair are unknown. We…”
Get full text

MEK1/2 Inhibition Promotes Macrophage Reparative Properties by Long, Matthew E, Eddy, William E, Gong, Ke-Qin, Lovelace-Macon, Lara L, McMahan, Ryan S, Charron, Jean, Liles, W Conrad, Manicone, Anne M

“…Macrophages have important functional roles in regulating the timely promotion and resolution of inflammation. Although many of the intracellular signaling…”
Get full text

A disintegrin and metalloproteinase 17 regulates TNF and TNFR1 levels in inflammation and liver regeneration in mice by McMahan, Ryan S, Riehle, Kimberly J, Fausto, Nelson, Campbell, Jean S

“…A disintegrin and metalloproteinase 17 (ADAM17), or tumor necrosis factor (TNF)-α-converting enzyme, is a key metalloproteinase and physiological convertase…”
Get more information

Toll‐like receptor 4 and myeloid differentiation factor 88 provide mechanistic insights into the cause and effects of interleukin‐6 activation in mouse liver regeneration by Vaquero, Javier, Campbell, Jean S., Haque, Jamil, McMahan, Ryan S., Riehle, Kimberly J., Bauer, Renay L., Fausto, Nelson

“…Partial hepatectomy (PH) consistently results in an early increase of circulating interleukin‐6 (IL‐6), which is thought to play a major role in liver…”
Get full text

Amphiphilic polymer-coated CdSe/ZnS quantum dots induce pro-inflammatory cytokine expression in mouse lung epithelial cells and macrophages by Lee, Vivian, McMahan, Ryan S., Hu, Xiaoge, Gao, Xiaohu, Faustman, Elaine M., Griffith, William C., Kavanagh, Terrance J., Eaton, David L., McGuire, John K., Parks, William C.

“…Abstract Quantum dots (Qdots) are semiconductor nanoparticles with size-tunable fluorescence capabilities with diverse applications. Qdots typically contain…”
Get full text

In vitro approaches to assessing the toxicity of quantum dots by McMahan, Ryan S, Lee, Vivian, Parks, William C, Kavanagh, Terrance J, Eaton, David L

“…Advances in nanotechnology have produced a new class of fluorescent nanoparticles known as quantum dots (Qdots). Compared with organic dyes and fluorescent…”
Get more information

MEK1/2 Inhibition Promotes Macrophage Reparative Properties1 by Long, Matthew E., Eddy, William E., Gong, Ke-Qin, Lovelace-Macon, Lara L., McMahan, Ryan S., Charron, Jean, Liles, W. Conrad, Manicone, Anne M.

“…Macrophages have important functional roles in regulating the timely promotion and resolution of inflammation. While many of the intracellular signaling…”
Get full text

Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice: Hepatitis Infection and hedgehog signaling p66Shc impairs liver regeneration in aged mice Mouse model of autoimmune pancreatitis by HAQUE, Jamil A, MCMAHAN, Ryan S, KAVANAGH, Terrance J, FAUSTO, Nelson, CAMPBELL, Jean S, SHIMIZU-ALBERGINE, Masami, WILSON, Angela M, BOTTA, Dianne, BAMMLER, Theo K, BEYER, Richard P, MONTINE, Thomas J, YEH, Matthew M

Get full text

The Role of TNF-alpha Converting Enzyme in Liver Injury and Regeneration by McMahan, Ryan S

“…TNF-α converting enzyme (TACE), also known as ADAM17, is a key metalloproteinase and physiological convertase with a number of putative targets that play…”
Get full text

Defining Advance Care Planning for Adults: A Consensus Definition From a Multidisciplinary Delphi Panel by Sudore, Rebecca L., MD, Lum, Hillary D., MD, PhD, You, John J., MD, Hanson, Laura C., MD, MPH, Meier, Diane E., MD, Pantilat, Steven Z., MD, Matlock, Daniel D., MD, MPH, Rietjens, Judith A.C., PhD, Korfage, Ida J., MSc, PhD, Ritchie, Christine S., MD, MSPH, Kutner, Jean S., MD, MSPH, Teno, Joan M., MD, MS, Thomas, Judy, JD, McMahan, Ryan D., BS, BA, Heyland, Daren K., MD, MSc

“…Abstract Context Despite increasing interest in advance care planning (ACP) and previous ACP descriptions, a consensus definition does not yet exist to guide…”
Get full text

Advance Care Planning Beyond Advance Directives: Perspectives From Patients and Surrogates by McMahan, Ryan D., BS, BA, Knight, Sara J., PhD, Fried, Terri R., MD, Sudore, Rebecca L., MD

“…Abstract Context Advance care planning (ACP) has focused on documenting life-sustaining treatment preferences in advance directives (ADs). The ADs alone may be…”
Get full text

What Is a Serious Medical Decision? Patients’ And Surrogates’ Perceptions of Serious Decisions and What Is Important in Making Them (S766) by Petrillo, Laura, MD, McMahan, Ryan, BS, Sudore, Rebecca, MD

Get full text

“Doctor, Make My Decisions”: Decision Control Preferences, Advance Care Planning, and Satisfaction With Communication Among Diverse Older Adults by Chiu, Catherine, BS, Feuz, Mariko A., BS, McMahan, Ryan D., BS, BA, Miao, Yinghui, MPH, Sudore, Rebecca L., MD

“…Abstract Context Culturally diverse older adults may prefer varying control over medical decisions. Decision control preferences (DCPs) may profoundly affect…”
Get full text

A Novel Website to Prepare Diverse Older Adults for Decision Making and Advance Care Planning: A Pilot Study (S763) by Sudore, Rebecca, MD, Knight, Sara, PhD, Feuz, Mariko, BS, Farrell, David, MPH, McMahan, Ryan, BS BA, Barnes, Deborah

Get full text

Family Matters: Effects of Birth Order, Culture, and Family Dynamics on Surrogate Decision Making (FR407-B) by Su, Christopher, BS, Sharma, Rashmi, MD MHS, Williams, Brie, MD, McMahan, Ryan, BS BA, Sudore, Rebecca, MD

Get full text