Search Results - "McLoughlin, C"

Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review by McLoughlin, Eavan C, O'Boyle, Niamh M

“…It is over 50 years since the discovery of microtubules, and they have become one of the most important drug targets for anti-cancer therapies. Microtubules…”
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Functional and cognitive outcomes after COVID-19 delirium by Mcloughlin, Benjamin C., Miles, Amy, Webb, Thomas E., Knopp, Paul, Eyres, Clodagh, Fabbri, Ambra, Humphries, Fiona, Davis, Daniel

“…Key summary points Aim To investigate functional and cognitive outcomes among patients with delirium in COVID-19. Findings Delirium in COVID-19 was prevalent…”
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Outcomes from COVID-19 across the range of frailty: excess mortality in fitter older people by Miles, Amy, Webb, Thomas E., Mcloughlin, Benjamin C., Mannan, Imran, Rather, Arshad, Knopp, Paul, Davis, Daniel

“…Key summary points Aim To describe associations between frailty, ethnicity, socioeconomic position and mortality in a cohort of older patients presenting to…”
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Long-Term Safety Profile and Off-Label Use of JAK Inhibitors in Dermatological Disorders by Corbella-Bagot, L., Riquelme-McLoughlin, C., Morgado-Carrasco, D.

“…[Display omitted] JAK inhibitors target specific inflammatory cytokines involved in various inflammatory diseases. Four molecules have been approved for…”
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Report of two cases of mucous membrane pemphigoid with frontal fibrosing alopecia: a variant of lichen planus pemphigoides or an incidental finding? by Bosch‐Amate, X., Riquelme‐McLoughlin, C., Morgado‐Carrasco, D., Rojano‐Fritz, L., Iranzo‐Fernández, P.

“…Summary Lichen planus pemphigoides (LPP) is a rare autoimmune subepidermal blistering disease characterized by the coexistence of both lichen planus and either…”
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Clozapine-induced interstitial nephritis in a patient with schizoaffective disorder in the forensic setting: a case report and review of the literature by McLoughlin, C, Cooney, C, Mullaney, R

“…We present a rare case of Acute Interstitial Nephritis (AIN) that occurred following a re-trial of clozapine in a 56-year-old lady with schizoaffective…”
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Factors affecting radiation exposure in patients undergoing endoscopic treatment for urolithiasis by Sugrue, D. D., Ryan, F., Courtney, M., Horan, M., Codd, M. B., McLoughlin, L. C., Lonergan, P. E., Manecksha, R. P.

“…Imaging techniques, such as computed tomography (CT) and fluoroscopy, are essential for the diagnosis and treatment of urolithiasis. There is increasing…”
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Correction: McLoughlin, E.C.; O'Boyle, N.M. Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review. Pharmaceuticals 2020, 13 , 8 by McLoughlin, Eavan C, O'Boyle, Niamh M

“…We, the authors, wish to make the following corrections to our paper[...]…”
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Standardized Reporting of Machine Learning Applications in Urology: The STREAM-URO Framework by Kwong, Jethro C.C., McLoughlin, Louise C., Haider, Masoom, Goldenberg, Mitchell G., Erdman, Lauren, Rickard, Mandy, Lorenzo, Armando J., Hung, Andrew J., Farcas, Monica, Goldenberg, Larry, Nguan, Chris, Braga, Luis H., Mamdani, Muhammad, Goldenberg, Anna, Kulkarni, Girish S.

“…The Standardized Reporting of Machine Learning Applications in Urology (STREAM-URO) framework was developed to provide a set of recommendations to help…”
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The Changing Paradigm of Management of Liver Abscesses in Chronic Granulomatous Disease by Straughan, David M, McLoughlin, Kaitlin C, Mullinax, John E, Marciano, Beatriz E, Freeman, Alexandra F, Anderson, Victoria L, Uzel, Gulbu, Azoury, Said C, Sorber, Rebecca, Quadri, Humair S, Malech, Harry L, DeRavin, Suk See, Kamal, Natasha, Koh, Christopher, Zerbe, Christa S, Kuhns, Douglas B, Gallin, John I, Heller, Theo, Holland, Steven M, Rudloff, Udo

“…Chronic granulomatous disease (CGD) is a rare genetic disorder causing recurrent infections. More than one-quarter of patients develop hepatic abscesses and…”
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Review article: the long‐term use of proton‐pump inhibitors by RAGHUNATH, A. S., O'MORAIN, C., MCLOUGHLIN, R. C.

“…Summary More than 15 years after the launch of omeprazole in 1988, proton‐pump inhibitors remain central to the management of acid‐suppression disorders and…”
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Application of 2D EXSY and qNMR Spectroscopy for Diastereomeric Excess Determination Following Chiral Resolution of β‐Lactams by McLoughlin, Eavan C., O'Brien, John E., Trujillo, Cristina, Meegan, Mary J., O'Boyle, Niamh M.

“…Trans‐β‐lactam isomers have garnered much attention as anti‐cancer microtubule targeting agents. Currently available synthetic methods are available for the…”
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Synthesis, Characterisation and Mechanism of Action of Anticancer 3-Fluoroazetidin-2-ones by Malebari, Azizah M, Duffy Morales, Gabriela, Twamley, Brendan, Fayne, Darren, Khan, Mohemmed Faraz, McLoughlin, Eavan C, O'Boyle, Niamh M, Zisterer, Daniela M, Meegan, Mary J

“…The stilbene combretastatin A-4 (CA-4) is a potent microtubule-disrupting agent interacting at the colchicine-binding site of tubulin. In the present work, the…”
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Clinical nomograms: Is a picture worth a thousand words? by McLoughlin, Kaitlin C., MD, Ripley, R. Taylor, MD

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Looks aren't everything, but neither is microRNA profiling by McLoughlin, Kaitlin C., MD, Ripley, R. Taylor, MD

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Knitting up the raveled sleave of care by Yang, Guangrui, Paschos, Georgios, Curtis, Anne M, Musiek, Erik S, McLoughlin, Sarah C, FitzGerald, Garret A

“…This Review is based on the Franklin Epstein Lecture delivered at Beth Israel Deaconess Hospital on 25 April 2013. We discuss recent advances in our…”
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A Novel Modular Mobile Power Flow Controller for Real-Time Congestion Management Tested on a 150kV Transmission System by Krommydas, Konstantinos F., Stratigakos, Akylas C., Dikaiakos, Christos N., Papaioannou, George P., Jones, Martin G., McLoughlin, Grace C.

“…Congestion issues are becoming more prevalent as the share of variable renewable energy increases. Conventional methods to mitigate them, such as building new…”
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Cannabis and schizophrenia by Pushpa-Rajah, Jonathan A, McLoughlin, Benjamin C, Gillies, Donna, Rathbone, John, Variend, Hannele, Kalakouti, Eliana, Kyprianou, Katerina

“…Many people with schizophrenia smoke cannabis, and it is unclear why a large proportion do so and if the effects are harmful or beneficial. It is also unclear…”
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Predictors of Return to Work in Cancer Survivors in the Royal Air Force by Murray, Kenneth, Lam, Kin Bong Hubert, McLoughlin, David C., Sadhra, Steven S.

“…Purpose Return to work (RTW) is beneficial for cancer survivors, employers and society. However, little is known about predictors of RTW in the military…”
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Long-Term Outcomes of Renal Transplant in Patients With End-Stage Renal Failure Due to Systemic Lupus Erythematosus and Granulomatosis With Polyangiitis by Considine, Shane W., Davis, Niall F., McLoughlin, Louise C., Mohan, Ponnusamy, Forde, James C., Power, Richard, Smyth, Gordon, Little, Dilly M.

“…Objectives: Systemic lupus erythematosus and granulomatosis with polyangiitis are systemic inflam - matory conditions associated with renal failure that can…”
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