Search Results - "McLeod, Shelley L"

Drug treatments for covid-19: living systematic review and network meta-analysis by Siemieniuk, Reed AC, Bartoszko, Jessica J, Ge, Long, Zeraatkar, Dena, Izcovich, Ariel, Kum, Elena, Pardo-Hernandez, Hector, Qasim, Anila, Martinez, Juan Pablo Díaz, Rochwerg, Bram, Lamontagne, Francois, Han, Mi Ah, Liu, Qin, Agarwal, Arnav, Agoritsas, Thomas, Chu, Derek K, Couban, Rachel, Cusano, Ellen, Darzi, Andrea, Devji, Tahira, Fang, Bo, Fang, Carmen, Flottorp, Signe Agnes, Foroutan, Farid, Ghadimi, Maryam, Heels-Ansdell, Diane, Honarmand, Kimia, Hou, Liangying, Hou, Xiaorong, Ibrahim, Quazi, Khamis, Assem, Lam, Bonnie, Loeb, Mark, Marcucci, Maura, McLeod, Shelley L, Motaghi, Sharhzad, Murthy, Srinivas, Mustafa, Reem A, Neary, John D, Rada, Gabriel, Riaz, Irbaz Bin, Sadeghirad, Behnam, Sekercioglu, Nigar, Sheng, Lulu, Sreekanta, Ashwini, Switzer, Charlotte, Tendal, Britta, Thabane, Lehana, Tomlinson, George, Turner, Tari, Vandvik, Per O, Vernooij, Robin WM, Viteri-García, Andrés, Wang, Ying, Yao, Liang, Ye, Zhikang, Guyatt, Gordon H, Brignardello-Petersen, Romina

“…AbstractObjectiveTo compare the effects of treatments for coronavirus disease 2019 (covid-19).DesignLiving systematic review and network meta-analysis.Data…”
Get full text

Defibrillation Strategies for Refractory Ventricular Fibrillation by Cheskes, Sheldon, Verbeek, P. Richard, Drennan, Ian R., McLeod, Shelley L., Turner, Linda, Pinto, Ruxandra, Feldman, Michael, Davis, Matthew, Vaillancourt, Christian, Morrison, Laurie J., Dorian, Paul, Scales, Damon C.

“…In a trial involving patients with refractory ventricular fibrillation, double sequential external defibrillation or vector-change defibrillation improved…”
Get full text

Prophylaxis against covid-19: living systematic review and network meta-analysis by Bartoszko, Jessica J, Siemieniuk, Reed A C, Kum, Elena, Qasim, Anila, Zeraatkar, Dena, Martinez, Juan Pablo Diaz, Azab, Maria, Ibrahim, Sara, Izcovich, Ariel, Soto, Gonzalo Bravo, Roldan, Yetiani, Agarwal, Arnav, Agoritsas, Thomas, Chu, Derek K, Couban, Rachel, Devji, Tahira, Foroutan, Farid, Ghadimi, Maryam, Honarmand, Kimia, Khamis, Assem, Lamontagne, Francois, Loeb, Mark, McLeod, Shelley L, Motaghi, Sharhzad, Murthy, Srinivas, Mustafa, Reem A, Rochwerg, Bram, Switzer, Charlotte, Thabane, Lehana, Vandvik, Per O, Vernooij, Robin W M, Wang, Ying, Yao, Liang, Guyatt, Gordon H, Brignardello-Petersen, Romina

“…This is the second version (first update) of the living systematic review, replacing the previous version (available as a data supplement). When citing this…”
Get more information

Remote Ischemic Perconditioning to Reduce Reperfusion Injury During Acute ST-Segment-Elevation Myocardial Infarction: A Systematic Review and Meta-Analysis by McLeod, Shelley L, Iansavichene, Alla, Cheskes, Sheldon

“…Remote ischemic conditioning (RIC) is a noninvasive therapeutic strategy that uses brief cycles of blood pressure cuff inflation and deflation to protect the…”
Get full text

Improving Access to Automated External Defibrillators in Rural and Remote Settings: A Drone Delivery Feasibility Study by Cheskes, Sheldon, McLeod, Shelley L, Nolan, Michael, Snobelen, Paul, Vaillancourt, Christian, Brooks, Steven C, Dainty, Katie N, Chan, Timothy C Y, Drennan, Ian R

“…Background Time to treatment is critical for survival from sudden cardiac arrest. Every minute delay in defibrillation results in a 7% to 10% reduction in…”
Get full text

“It saved me from the emergency department”: A qualitative study of patient experience of virtual urgent care in Ontario by Dainty, Katie N, Seaton, M. Bianca, Hall, Justin N, Mondoux, Shawn, Abraham, Lency, McCarron, Joy, Tarride, Jean-Eric, McLeod, Shelley L

“…Introduction In response to the COVID-19 pandemic, the Ontario Ministry of Health introduced a pilot program of 14 virtual urgent care (VUC) initiatives across…”
Get full text

Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis by Alexander, Paul E., Barty, Rebecca, Fei, Yutong, Vandvik, Per Olav, Pai, Menaka, Siemieniuk, Reed A.C., Heddle, Nancy M., Blumberg, Neil, McLeod, Shelley L., Liu, Jianping, Eikelboom, John W., Guyatt, Gordon H.

“…The impact of transfusing fresher vs older red blood cells (RBCs) on patient-important outcomes remains controversial. Two recently published large trials have…”
Get full text

Cost Evaluation of the Ontario Virtual Urgent Care Pilot Program: Population-Based, Matched Cohort Study by Tarride, Jean-Eric, Hall, Justin N, Mondoux, Shawn, Dainty, Katie N, McCarron, Joy, Paterson, J Michael, Plumptre, Lesley, Borgundvaag, Emily, Ovens, Howard, McLeod, Shelley L

“…In 2020, the Ministry of Health (MoH) in Ontario, Canada, introduced a virtual urgent care (VUC) pilot program to provide alternative access to urgent care…”
Get full text

Risk of intracranial hemorrhage between different direct oral anticoagulants in older patients seen in the emergency department with a head injury: A population-based cohort study by Grewal, Keerat, Atzema, Clare L., Austin, Peter C., de Wit, Kerstin, Sharma, Sunjay, Mittmann, Nicole, Borgundvaag, Bjug, McLeod, Shelley L.

“…Patients taking direct oral anticoagulants (DOACs) are increasingly managed in emergency departments (ED). It is unknown whether the risk of traumatic…”
Get full text

Adverse effects of remdesivir, hydroxychloroquine and lopinavir/ritonavir when used for COVID-19: systematic review and meta-analysis of randomised trials by Izcovich, Ariel, Siemieniuk, Reed Alexander, Bartoszko, Jessica Julia, Ge, Long, Zeraatkar, Dena, Kum, Elena, Qasim, Anila, Khamis, Assem M, Rochwerg, Bram, Agoritsas, Thomas, Chu, Derek K, McLeod, Shelley L, Mustafa, Reem A, Vandvik, Per, Brignardello-Petersen, Romina

“…BackgroundTo summarise specific adverse effects of remdesivir, hydroxychloroquine and lopinavir/ritonavir in patients with COVID-19.MethodsWe searched 32…”
Get full text

Impact of an intergenerational program to improve loneliness and social isolation in older adults initiated at the time of emergency department discharge: study protocol for a three-arm randomized clinical trial by Zheng, David, Rose, Louise, Borgundvaag, Bjug, McLeod, Shelley L, Melady, Donald, Mohindra, Rohit, Sinha, Samir, Wesson, Virginia, Wiesenfeld, Lesley, Kolker, Sabrina, Kiss, Alex, Lowthian, Judy A, Lee, Jacques S

“…Social isolation and loneliness (SIL) worsens mortality and other outcomes among older adults as much as smoking. We previously tested the impact of the HOW R…”
Get full text

Randomized controlled trials in resuscitation by Drennan, Ian R., McLeod, Shelley L., Cheskes, Sheldon

“…•Clinical trials are vital to the advancement of resuscitation science.•The out-of-hospital setting is a complex and uncontrolled environment. Planning…”
Get full text

Impact of a peer-support programme to improve loneliness and social isolation due to COVID-19: does adding a secure, user friendly video-conference solution work better than telephone support alone? Protocol for a three-arm randomised clinical trial by Lee, Jacques Simon, Rose, Louise, Borgundvaag, Bjug, McLeod, Shelley L, Melady, Donald, Mohindra, Rohit, Sinha, Samir K, Wesson, Virginia, Wiesenfeld, Lesley, Kolker, Sabrina, Kiss, Alex, Lowthian, Judy

“…IntroductionThe COVID-19 pandemic has forced the implementation of physical distancing and self-isolation strategies worldwide. However, these measures have…”
Get full text

Characterizing Risk Factors for Hospitalization and Clinical Characteristics in a Cohort of COVID-19 Patients Enrolled in the GENCOV Study by Morgan, Gregory, Casalino, Selina, Chowdhary, Sunakshi, Frangione, Erika, Fung, Chun Yiu Jordan, Haller, Simona, Lapadula, Elisa, Scott, Mackenzie, Wolday, Dawit, Young, Juliet, Arnoldo, Saranya, Aujla, Navneet, Bearss, Erin, Binnie, Alexandra, Bombard, Yvonne, Borgundvaag, Bjug, Briollais, Laurent, Dagher, Marc, Devine, Luke, Faghfoury, Hanna, Friedman, Steven M, Gingras, Anne-Claude, Goneau, Lee W, Khan, Zeeshan, Mazzulli, Tony, McLeod, Shelley L, Nomigolzar, Romina, Noor, Abdul, Pugh, Trevor J, Richardson, David, Satnam Singh, Harpreet Kaur, Simpson, Jared, Stern, Seth, Strug, Lisa, Taher, Ahmed, Lerner-Ellis, Jordan, Taher, Jennifer

“…The GENCOV study aims to identify patient factors which affect COVID-19 severity and outcomes. Here, we aimed to evaluate patient characteristics, acute…”
Get full text

Implementation of serological and molecular tools to inform COVID-19 patient management: protocol for the GENCOV prospective cohort study by Taher, Jennifer, Mighton, Chloe, Chowdhary, Sunakshi, Casalino, Selina, Frangione, Erika, Arnoldo, Saranya, Bearss, Erin, Binnie, Alexandra, Bombard, Yvonne, Borgundvaag, Bjug, Chertkow, Howard, Clausen, Marc, Devine, Luke, Faghfoury, Hanna, Friedman, Steven Marc, Gingras, Anne-Claude, Khan, Zeeshan, Mazzulli, Tony, McGeer, Allison, McLeod, Shelley L, Pugh, Trevor J, Richardson, David, Simpson, Jared, Stern, Seth, Strug, Lisa, Taher, Ahmed, Lerner-Ellis, Jordan

“…IntroductionThere is considerable variability in symptoms and severity of COVID-19 among patients infected by the SARS-CoV-2 virus. Linking host and virus…”
Get full text

Point-of-care ultrasound-guided regional anaesthesia in older ED patients with hip fractures: a study to test the feasibility of a training programme and time needed to complete nerve blocks by ED physicians after training by Lee, Jacques Simon, Bhandari, Tina, Simard, Robert, Emond, Marcel, Topping, Claude, Woo, Michael, Perry, Jeffrey, Eagles, Debra, McRae, Andrew D, Lang, Eddy, Wong, Charles, Sivilotti, Marco, Newbigging, Joseph, Borgundvaag, Bjug, McLeod, Shelley L, Melady, Donald, Chernoff, Lan, Kiss, Alex, Chenkin, Jordan

“…ObjectivesPoint-of-care ultrasound-guided regional anaesthesia (POCUS-GRA) provides safe, rapid analgesia for older people with hip fractures but is rarely…”
Get full text

Which older emergency patients are at risk of intracranial bleeding after a fall? A protocol to derive a clinical decision rule for the emergency department by de Wit, Kerstin, Mercuri, Mathew, Clayton, Natasha, Worster, Andrew, Mercier, Eric, Emond, Marcel, Varner, Catherine, McLeod, Shelley L, Eagles, Debra, Stiell, Ian, Barbic, David, Morris, Judy, Jeanmonod, Rebecca, Kagoma, Yoan, Shoamanesh, Ashkan, Engels, Paul T, Sharma, Sunjay, Kearon, Clive, Papaioannou, Alexandra, Parpia, Sameer

“…IntroductionFalling on level ground is now the most common cause of traumatic intracranial bleeding worldwide. Older adults frequently present to the emergency…”
Get full text

Designs, facilitators, barriers, and lessons learned during the implementation of emergency department led virtual urgent care programs in Ontario, Canada by Hall, Justin N, Ackery, Alun D, Dainty, Katie N, Gill, Paul S, Lim, Rodrick, Masood, Sameer, McLeod, Shelley L, Mehta, Shaun D, Nijmeh, Larry, Rosenfield, Daniel, Rutledge, Greg, Verma, Aikta, Mondoux, Shawn

“…Virtual patient care has seen incredible growth since the beginning of the COVID-19 pandemic. To provide greater access to safe and timely urgent care, in the…”
Get full text

Low‐dose Ketamine For Acute Pain Control in the Emergency Department: A Systematic Review and Meta‐analysis by Balzer, Nathan, McLeod, Shelley L., Walsh, Chris, Grewal, Keerat, Miner, James

“…Objective There has been increased interest in the use of low‐dose ketamine (LDK) as an alternative analgesic for the management of acute pain in the emergency…”
Get full text

Risk Factors Associated with Urologic Intervention in Emergency Department Patients with Suspected Renal Colic by Yan, Justin W., MD, MSc, FRCPC, McLeod, Shelley L., MSc, Edmonds, Marcia L., MD, FRCPC, MSc, Sedran, Robert J., MD, FRCPC, MSc, Theakston, Karl D., MD, MSc

“…Abstract Background Whereas most patients with urolithiasis pass their stones spontaneously and require only symptomatic management, a minority will require…”
Get full text