Search Results - "McLean, Derek J"

The Murine Testicular Transcriptome: Characterizing Gene Expression in the Testis During the Progression of Spermatogenesis by SHIMA, James E, MCLEAN, Derek J, MCCARREY, John R, GRISWOLD, Michael D

“…One of the most promising applications of microarrays is the study of changes in gene expression associated with the growth and development of mammalian…”
Get full text

A natural bioactive feed additive alters expression of genes involved in inflammation in whole blood of healthy Angus heifers by Armstrong, Shelby A, McLean, Derek J, Bionaz, Massimo, Bobe, Gerd

“…A greater demand for food animal production without antibiotics has created the common practice of feeding food animals dietary immunomodulatory feed additives…”
Get full text

Water buffalo genome science comes of age by Michelizzi, Vanessa N, Dodson, Michael V, Pan, Zengxiang, Amaral, M Elisabete J, Michal, Jennifer J, McLean, Derek J, Womack, James E, Jiang, Zhihua

“…The water buffalo is vital to the lives of small farmers and to the economy of many countries worldwide. Not only are they draught animals, but they are also a…”
Get full text

Vascular endothelial growth factor regulates germ cell survival during establishment of spermatogenesis in the bovine testis by Caires, Kyle C, de Avila, Jeanene, McLean, Derek J

“…Vascular endothelial growth factor-A (VEGFA) is a hypoxia-inducible peptide essential for angiogenesis and targets nonvascular cells in a variety of tissues…”
Get full text

Novel vein closure procedure using a proprietary cyanoacrylate adhesive: 30-day swine model results by Min, Robert J, Almeida, Jose I, McLean, Derek J, Madsen, Monte, Raabe, Rodney

“…To conduct a pilot study to demonstrate a novel method of using a proprietary cyanoacrylate (CA) for closure of superficial veins. Right and left superficial…”
Get more information

Characterization of Spermatogonial Stem Cell Maturation and Differentiation in Neonatal Mice by MCLEAN, Derek J, FRIEL, Patrick J, JOHNSTON, Daniel S, GRISWOLD, Michael D

“…Initiation of the first wave of spermatogenesis in the neonatal mouse testis is characterized by the differentiation of a transient population of germ cells…”
Get full text

Transgenerational effects of di-(2-ethylhexyl) phthalate on testicular germ cell associations and spermatogonial stem cells in mice by Doyle, Timothy J, Bowman, Jennifer L, Windell, Veronica L, McLean, Derek J, Kim, Kwan Hee

“…Recent evidence has linked human phthalate exposure to abnormal reproductive and hormonal effects. Phthalates are plasticizers that confer flexibility and…”
Get full text

Biological Activity of Cryopreserved Bovine Spermatogonial Stem Cells During In Vitro Culture by OATLEY, Jon M, REEVES, Jerry J, MCLEAN, Derek J

“…Functional roles of spermatogonial stem cells in spermatogenesis are self-renewing proliferation and production of differentiated daughter progeny. The ability…”
Get full text

A global view of 54,001 single nucleotide polymorphisms (SNPs) on the Illumina BovineSNP50 BeadChip and their transferability to water buffalo by Michelizzi, Vanessa N, Wu, Xiaolin, Dodson, Michael V, Michal, Jennifer J, Zambrano-Varon, Jorge, McLean, Derek J, Jiang, Zhihua

“…The Illumina BovineSNP50 BeadChip features 54,001 informative single nucleotide polymorphisms (SNPs) that uniformly span the entire bovine genome. Among them,…”
Get full text

Spermatogenesis and Germ Cell Transgene Expression in Xenografted Bovine Testicular Tissue by OATLEY, Jon M, DE AVILA, David M, REEVES, Jerry J, MCLEAN, Derek J

“…The present study was conducted to evaluate the development of spermatogenesis and utility of using electroporation to stably transfect germ cells with the…”
Get full text

Enhanced Genetic Integrity in Mouse Germ Cells1 by Murphey, Patricia, McLean, Derek J, McMahan, C. Alex, Walter, Christi A, McCarrey, John R

“…Genetically based diseases constitute a major human health burden, and de novo germline mutations represent a source of heritable genetic alterations that can…”
Get full text

Establishment of Spermatogenesis in Neonatal Bovine Testicular Tissue Following Ectopic Xenografting Varies with Donor Age by OATLEY, Jon M, REEVES, Jerry J, MCLEAN, Derek J

“…Ectopic testicular xenografting can be used to investigate spermatogenesis and as an alternative means for generating transgenic spermatozoa in many species…”
Get full text

Transgenerational Effects of Di-(2-ethylhexyl) Phthalate on Testicular Germ Cell Associations and Spermatogonial Stem Cells in Mice1 by Doyle, Timothy J, Bowman, Jennifer L, Windell, Veronica L, McLean, Derek J, Kim, Kwan Hee

“…Recent evidence has linked human phthalate exposure to abnormal reproductive and hormonal effects. Phthalates are plasticizers that confer flexibility and…”
Get full text

Effect of Vascular Endothelial Growth Factor and Testis Tissue Culture on Spermatogenesis in Bovine Ectopic Testis Tissue Xenografts by Schmidt, Jonathan A, Avila, Jeanene Mde, McLean, Derek J

“…Bovine ectopic testis tissue grafting is a technique that can be used to study bovine spermatogenesis and for the production of germ cells for a variety of…”
Get full text

Analysis of Gene Expression in Bovine Testis Tissue Prior to Ectopic Testis Tissue Xenografting and During the Grafting Period by SCHMIDT, Jonathan A, DE AVILA, Jeanene M, MCLEN, Derek J

“…The purpose of this study was to identify factors that contribute to bovine testis development and donor age-dependent differences in the abilities of bovine…”
Get full text

Endocrine regulation of spermatogonial stem cells in the seminiferous epithelium of adult mice by Caires, Kyle C, de Avila, Jeanene, McLean, Derek J

“…A balance between self-renewal and differentiation of spermatogonial stem cells (SSCs) is required to maintain sperm production throughout male life. The…”
Get full text

Biological Activity and Enrichment of Spermatogonial Stem Cells in Vitamin A-Deficient and Hyperthermia-Exposed Testes from Mice Based on Colonization Following Germ Cell Transplantation by MCLEAN, Derek J, RUSSELL, Lonnie D, GRISWOLD, Michael D

“…Spermatogenesis is a complex process in which spermatogonial stem cells divide and subsequently differentiate into spermatozoa. This process requires…”
Get full text

Effect of nutritional immunomodulation and heat stress during the dry period on subsequent performance of cows by Fabris, Thiago F, Laporta, Jimena, Corra, Fabiana N, Torres, Yazielis M, Kirk, David J, McLean, Derek J, Chapman, J D, Dahl, Geoffrey E

“…Heat stress in dairy cows during the dry period impairs milk yield in the next lactation. Feeding OmniGen-AF (OG; Phibro Animal Health Corp., Teaneck, NJ) to…”
Get more information

Grafting Period and Donor Age Affect the Potential for Spermatogenesis in Bovine Ectopic Testis Xenografts by Schmidt, Jonathan A, Avila, Jeanene Mde, McLean, Derek J

“…Bovine testis tissue xenografts contain elongating spermatids 6 mo after grafting. The percentage of seminiferous tubule cross sections with elongating…”
Get full text

Testis Tissue Explant Culture Supports Survival and Proliferation of Bovine Spermatogonial Stem Cells by OATLEY, Jon M, DE AVILA, David M, REEVES, Jerry J, MCLEAN, Derek J

“…The present study was designed to evaluate the survival and proliferation of bovine spermatogonial stem cells in an explant culture system over a 2-wk period…”
Get full text