Search Results - "McLean, C. S."

A Genetically Inactivated Herpes Simplex Virus Type 2 (HSV-2) Vaccine Provides Effective Protection against Primary and Recurrent HSV-2 Disease by Boursnell, M. E. G., Entwisle, C., Blakeley, D., Roberts, C., Duncan, I. A., Chisholm, S. E., Martin, G. M., Jennings, R., Ní Challanaín, D., Sobek, I., Inglis, S. C., McLean, C. S.

“…A glycoprotein H (gH)-deleted herpes simplex virus type 2 (HSV-2) was evaluated as a vaccine for the prevention of HSV-induced disease. This virus, which we…”
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Vaccine potential of a herpes simplex virus type 1 mutant with an essential glycoprotein deleted by FARRELL, H. E, MCLEAN, C. S, HARLEY, C, EFSTATHIOU, S, INGLIS, S, MINSON, A. C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Construction and characterisation of a recombinant vaccinia virus expressing human papillomavirus proteins for immunotherapy of cervical cancer by Boursnell, M.E.G., Rutherford, E., Hickling, J.K., Rollinson, E.A., Munro, A.J., Rolley, N., McLean, C.S., Borysiewicz, L.K., Vousden, K., Inglis, S.C.

“…The presence and consistent expression of the genes encoding the human papillomavirus (HPV) E6 and E7 proteins in the great majority of cervical tumours…”
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Preclinical evaluation of whole cell vaccines for prophylaxis and therapy using a disabled infectious single cycle-herpes simplex virus vector to transduce cytokine genes by ALI, S. A, MCLEAN, C. S, VILE, R, ROBINS, R. A, REES, R. C, BOURSNELL, M. E. G, MARTIN, G, HOLMES, C. L, REEDER, S, ENTWISLE, C, BLAKELEY, D. M, SHIELDS, J. G, TODRYK, S

“…The development of genetically modified "whole" tumor cell vaccines for cancer therapy relies on the efficient transduction and expression of genes by vectors…”
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Induction of a protective immune response by mucosal vaccination with a DISC HSV-1 vaccine by McLean, C.S., NíChallanáin, D., Duncan, I., Boursnell, M.E.G., Jennings, R., Inglis, S.C.

“…The vaccine potential of a genetically disabled Herpes Simplex Virus Type 1 virus (DISC HSV-1) was investigated in the guinea pig model of intravaginal…”
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Protective Vaccination Against Primary And Recurrent Disease Caused By Herpes Simplex Virus (HSV) Type 2 Using A Genetically Disabled HSV-1 by Mclean, C. S., Erturk, M., Jennings, R., Ni Challanain, D., Minson, A. C., Duncan, I., Boursnell, M. E. G., Inglis, S. C.

“…The vaccine potential of a mutant herpes simplex virus (HSV) type 1, with a deletion in the glycoprotein H (gH) gene, was evaluated. The virus requires a…”
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Production and characterisation of a monoclonal antibody to human papillomavirus type 16 using recombinant vaccinia virus by McLean, C S, Churcher, M J, Meinke, J, Smith, G L, Higgins, G, Stanley, M, Minson, A C

“…A monoclonal antibody was raised against the major capsid protein L1 of human papillomavirus type 16, using a recombinant vaccinia virus that expresses the L1…”
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Delayed-type hypersensitivity response to the human papillomavirus type 16 E7 protein in a mouse model by McLean, Cornelia S, Sterling, Jane S, Mowat, Justine, Nash, Anthony A, Stanley, Margaret A

“…Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, U.K. To study the immune response to human papillomavirus type 16, a…”
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Identification of the nuclear localization signal of human papillomavirus type 16 L1 protein by Zhou, J, Doorbar, J, Sun, X Y, Crawford, L V, McLean, C S, Frazer, I H

“…Human papillomavirus type 16(HPV16) L1 and L2 capsid proteins can be detected only in the nucleus of infected cells. For other nuclear proteins, specific…”
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A critical review of comprehensive health screening in adolescents by CROMER, B. A, MCLEAN, C. S, HEALD, F. P

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Anti-tumour therapeutic efficacy of OX40L in murine tumour model by Ali, Selman A., Ahmad, Murrium, Lynam, June, McLean, Cornelia S., Entwisle, Claire, Loudon, Peter, Choolun, Esther, McArdle, Stephanie E.B., Li, Geng, Mian, Shahid, Rees, Robert C.

“…OX40 ligand (OX40L), a member of TNF superfamily, is a co-stimulatory molecule involved in T cell activation. Systemic administration of mOX40L fusion protein…”
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Pathogenesis of Herpes Simplex Virus in Congenitally Athymic Mice: the Relative Roles of Cell-mediated and Humoral Immunity by Kapoor, A. K, Nash, A. A, Wildy, P, Phelan, J, McLean, C. S, Field, H. J

“…Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, U.K. Athymic nude (nu/nu) mice were inoculated in the ear pinna with 10…”
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Disabled infectious single cycle (DISC) herpes simplex virus as a vector for immunotherapy of cancer by Boursnell, M E, Entwisle, C, Ali, S A, Sivasubramaniam, S D, Reeder, S, McLean, C S, Blakeley, D M, Miller, J, Hill, S, Shields, J G, Inglis, S C, Rees, R C

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An algorithm for simultaneous stabilization using decentralized constant gain output feedback by Broussard, J.R., McLean, C.S.

“…An algorithm which solves, numerically, the simultaneous stabilization problem using a constant gain decentralized control law is presented. The algorithm is…”
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Tumor Regression Induced by Intratumor Therapy with a Disabled Infectious Single Cycle (DISC) Herpes Simplex Virus (HSV) Vector, DISC/HSV/Murine Granulocyte-Macrophage Colony-Stimulating Factor, Correlates with Antigen-Specific Adaptive Immunity by Ali, Selman A, Lynam, June, McLean, Cornelia S, Entwisle, Claire, Loudon, Peter, Rojas, Jose M, McArdle, Stephanie E. B, Li, Geng, Mian, Shahid, Rees, Robert C

“…Direct intratumor injection of a disabled infectious single cycle HSV-2 virus encoding the murine GM-CSF gene (DISC/mGM-CSF) into established murine colon…”
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The use of monoclonal antibodies to differentiate isolates of herpes simplex types 1 and 2 by neutralisation and reverse passive haemagglutination tests by Buckmaster, E A, Cranage, M P, McLean, C S, Coombs, R R, Minson, A

“…Monoclonal antibodies specific for herpes simplex type 1 or type 2 were used in reverse passive haemagglutination tests or infectivity neutralisation tests to…”
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Preclinical evaluation of DISC-GMCSF for the treatment of breast carcinoma by Loudon, Peter T., McLean, Cornelia S., Martin, Gilly, Curry, Jayne, Leigh Shaw, M., Hoogstraten, Conny, Verdegaal, Els, Osanto, Susanne

“…Background DISC‐hGMCSF is a gH‐deleted HSV‐2 based vector expressing human GM‐CSF that has entered clinical trials for the therapy of metastatic melanoma. To…”
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Preclinical safety testing of DISC-hGMCSF to support phase I clinical trials in cancer patients by Loudon, Peter T., Blakeley, Diane M., Boursnell, Mike E. G., Day, Debbie A., Duncan, Imogen A., Lowden, Richard C., McLean, Cornelia S., Martin, Gilly, Miller, Jayne C., Leigh Shaw, M.

“…Background DISC‐hGMCSF is a gH‐deleted HSV‐2 based vector expressing human GM‐CSF that is being developed for cancer immunotherapy. To support first clinical…”
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Evaluating the sexually active adolescent: identification of behavioral and biologic risk factors by McLean, C S, Farmer, M

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The use of monoclonal antibodies in (reverse) passive haemagglutination tests for herpes simplex virus antigens and antibodies by Cranage, M P, McLean, C S, Buckmaster, E A, Minson, A C, Wildy, P, Coombs, R R

“…Three monoclonal antibodies against herpes simplex virus type 2 have been tested for their suitability as reagents in reverse passive haemagglutination. Two of…”
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