Search Results - "McLaughlin, P. J"

Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice by Jackson, K. J., McLaughlin, J. P., Carroll, F. I., Damaj, M. I.

“…Rationale Several studies implicate stress as a risk factor for the development and maintenance of drug addictive behaviors and drug relapse. Kappa opioid…”
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Reinstatement of cocaine place-conditioning prevented by the peptide kappa-opioid receptor antagonist arodyn by Carey, A.N., Borozny, K., Aldrich, J.V., McLaughlin, J.P.

“…Stress contributes to the reinstatement of cocaine-seeking behavior in abstinent subjects. Kappa-opioid receptor antagonists attenuate the behavioral effects…”
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The cannabinoid CB1 antagonists SR 141716A and AM 251 suppress food intake and food-reinforced behavior in a variety of tasks in rats by McLaughlin, P. J, Winston, K, Swezey, L, Wisniecki, A, Aberman, J, Tardif, D. J, Betz, A. J, Ishiwari, K, Makriyannis, A, Salamone, J. D

“…Cannabinoid CB1 receptor agonists, including delta-9-tetrahydrocannabinol (Δ-THC) (the main psychoactive ingredient in marijuana) have been shown to increase…”
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The cannabinoid CB1 antagonist AM 251 produces food avoidance and behaviors associated with nausea but does not impair feeding efficiency in rats by MCLAUGHLIN, P. J, WINSTON, K. M, LIMEBEER, C. L, PARKER, L. A, MAKRIYANNIS, A, SALAMONE, J. D

“…A growing body of evidence suggests that cannabinoid CB1 receptor antagonists have potential therapeutic utility as appetite suppressants. However, the…”
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Optical and physical properties of primary on-road vehicle particle emissions and their implications for climate change by Strawa, A.W., Kirchstetter, T.W., Hallar, A.G., Ban-Weiss, G.A., McLaughlin, J.P., Harley, R.A., Lunden, M.M.

“…During the summers of 2004 and 2006, extinction and scattering coefficients of particle emissions inside a San Francisco Bay Area roadway tunnel were measured…”
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Structure of gelsolin segment 1-actin complex and the mechanism of filament severing by McLaughlin, P. J, Gooch, J. T, Mannherz, H.-G, Weeds, A. G

“…The structure of the segment 1 domain of gelsolin, a protein that fragments actin filaments in cells, is reported in complex with actin. Segment 1 binds…”
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Dopamine receptor expression on human T- and B-lymphocytes, monocytes, neutrophils, eosinophils and NK cells: a flow cytometric study by McKenna, F, McLaughlin, P.J, Lewis, B.J, Sibbring, G.C, Cummerson, J.A, Bowen-Jones, D, Moots, R.J

“…This study documents expression of dopamine (DA) receptors on leukocyte subpopulations using flow cytometric techniques to identify dopamine receptors with…”
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Gonadectomy Impairs T-Maze Acquisition in Adult Male Rats by Kritzer, M.F., McLaughlin, P.J., Smirlis, T., Robinson, J.K.

“…Recent studies have shown that chronic gonadectomy increases the density of dopaminergic axons in prefrontal but not sensorimotor cortices in adult male rats…”
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Estimating the Minimum Number of Judges Required for Test-centred Standard Setting on Written Assessments. Do Discussion and Iteration have an Influence? by Fowell, S. L., Fewtrell, R., McLaughlin, P. J.

“…Absolute standard setting procedures are recommended for assessment in medical education. Absolute, test-centred standard setting procedures were introduced…”
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Detailed analysis of food-reinforced operant lever pressing distinguishes effects of a cannabinoid CB1 inverse agonist and dopamine D1 and D2 antagonists by McLaughlin, P.J., Winston, K.M., Swezey, L.A., Vemuri, V.K., Makriyannis, A., Salamone, J.D.

“…Overt similarities exist between the effects of systemic cannabinoid CB1 inverse agonists and dopamine (DA) antagonists on appetitive behavior. The present set…”
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Digenean metacercariae of fishes from the lagoon flats of Palmyra Atoll, Eastern Indo-Pacific by Vidal-Martínez, V M, Aguirre-Macedo, M L, McLaughlin, J P, Hechinger, R F, Jaramillo, A G, Shaw, J C, James, A K, Kuris, A M, Lafferty, K D

“…Although many studies on the taxonomy of digenean trematodes of marine fishes have been completed in the Eastern Indo-Pacific (EIP) marine ecoregion, only a…”
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Old drug, new tricks: haloperidol inhibits secretion of proinflammatory cytokines by Moots, R J, Al-Saffar, Z, Hutchinson, D, Golding, S P, Young, S P, Bacon, P A, McLaughlin, P J

“…OBJECTIVES It was noted that treatment of a patient with acute mania by haloperidol was associated with marked improvement in activity of rheumatoid arthritis…”
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Opioid growth factor and organ development in rat and human embryos by Zagon, Ian S, Wu, Yan, McLaughlin, Patricia J

“…In addition to neurotransmission, the native opioid peptide, [Met 5]enkephalin, is a tonically active inhibitory growth molecule that is termed opioid growth…”
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Regulation of DNA synthesis of myocardial and epicardial cells in developing rat heart by [Met5]enkephalin by McLaughlin, P J

“…Endogenous opioids serve as negative growth factors in neural and nonneural tissues in addition to being neuromodulators. This study investigated the…”
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Diversified prime and boost protocols using recombinant vaccinia virus and recombinant non-replicating avian pox virus to enhance T-cell immunity and antitumor responses by Hodge, James W., McLaughlin, Joanne P., Kantor, Judith A., Schlom, Jeffrey

“…Recombinant vaccinia viruses containing tumor associated genes represent an attractive vector to induce immune responses to weak immunogens in cancer…”
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Immunolocalization of tumour necrosis factor-α (TNF-α) in the placental bed of normotensive and hypertensive human pregnancies by Pijnenborg, R., McLaughlin, P.J., Vercruysse, L., Hanssens, M., Johnson, P.M., Keith, J.C., Van Assche, F.A.

“…To identify tumour necrosis factor (TNF)-γ immunopositive cells, third trimester human placental bed biopsies were selected from nine normotensive control…”
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Pharmacological characterization of 2-methyl-N-((2'-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a high-affinity antagonist selective for κ-opioid receptors by Grimwood, S, Lu, Y, Schmidt, A W, Vanase-Frawley, M A, Sawant-Basak, A, Miller, E, McLean, S, Freeman, J, Wong, S, McLaughlin, J P, Verhoest, P R

“…2-Methyl-N-((2'-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242) is a novel κ-opioid receptor (KOR) antagonist with high affinity for…”
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The novel cannabinoid agonist AM 411 produces a biphasic effect on accuracy in a visual target detection task in rats by McLaughlin, P. J, Brown, C. M, Winston, K. M, Thakur, G, Lu, D, Makriyannis, A, Salamone, J. D

“…Cannabinoid agonists have been shown to produce dose-related impairments in several measures of cognitive performance. However, it is unclear if low doses of…”
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Integrated natural radiation exposure studies in stable Yugoslav rural communities by Zunic, Z.S., McLaughlin, J.P., Walsh, C., Birovljev, A., Simopoulos, S.E., Jakupi, B., Gordanic, V., Demajo, M., Trotti, F., Falk, R., Vanmarcke, H., Paridaens, J., Fujimoto, K.

“…The results of field investigations of natural radiation exposures of the general population in two stable rural communities in Yugoslavia are presented. The…”
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Reepithelialization of the Human Cornea Is Regulated by Endogenous Opioids by Zagon, Ian S, Sassani, Joseph W, McLaughlin, Patricia J

“…To determine the influence of endogenous opioid modulation on reepithelialization of the human cornea. Eight-millimeter-diameter epithelial defects were…”
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