Search Results - "McLatchie, Linda M."

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor by Foord, Steven M, McLatchie, Linda M, Fraser, Neil J, Main, Martin J, Wise, Alan, Brown, Jason, Thompson, Nicola, Solari, Roberto, Lee, Melanie G

“…Calcitonin-gene-related peptide (CGRP) and adrenomedullin are related peptides with distinct pharmacological profiles. Here we show that a receptor with seven…”
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Esmolol cardioplegia: the cellular mechanism of diastolic arrest by Fallouh, Hazem B., Bardswell, Sonya C., McLatchie, Linda M., Shattock, Michael J., Chambers, David J., Kentish, Jonathan C.

“…Aims Esmolol, an ultra-short-acting β-blocker, acts as a cardioplegic agent at millimolar concentrations. We investigated the mechanism by which esmolol…”
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Pharmacological differences between the human and rat vanilloid receptor 1 (VR1) by McIntyre, Peter, McLatchie, Linda M, Chambers, Anne, Phillips, Elsa, Clarke, Melanie, Savidge, Jonathan, Toms, Christy, Peacock, Marcus, Shah, Kirti, Winter, Janet, Weerasakera, Natasha, Webb, Mike, Rang, Humphrey P, Bevan, Stuart, James, Iain F

“…Vanilloid receptors (VR1) were cloned from human and rat dorsal root ganglion libraries and expressed in Xenopus oocytes or Chinese Hamster Ovary (CHO) cells…”
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ATP release from freshly isolated guinea‐pig bladder urothelial cells: a quantification and study of the mechanisms involved by McLatchie, Linda M., Fry, Christopher H.

“…Objectives To quantify the amount of ATP released from freshly isolated bladder urothelial cells, study its control by intracellular and extracellular calcium…”
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Could a dye offer a cheap and simple approach to detect bladder cancer using white‐light cystoscopy? by McLatchie, Linda M.

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The rate of loss of T‐tubules in cultured adult ventricular myocytes is species dependent by Pavlović, Davor, McLatchie, Linda M., Shattock, Michael J.

“…In this study, we compared the rate of detubulation of adult mouse and rat ventricular myocytes over a 72 h culture period. The T‐tubule density was measured…”
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FXYD1 phosphorylation in vitro and in adult rat cardiac myocytes: threonine 69 is a novel substrate for protein kinase C by Fuller, William, Howie, Jacqueline, McLatchie, Linda M, Weber, Roberta J, Hastie, C James, Burness, Kerry, Pavlovic, Davor, Shattock, Michael J

“…FXYD1 (phospholemman), the primary sarcolemmal kinase substrate in the heart, is a regulator of the cardiac sodium pump. We investigated phosphorylation of…”
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A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle by Wypijewski, Krzysztof J, Howie, Jacqueline, Reilly, Louise, Tulloch, Lindsay B, Aughton, Karen L, McLatchie, Linda M, Shattock, Michael J, Calaghan, Sarah C, Fuller, William

“…Phospholemman regulates the plasmalemmal sodium pump in excitable tissues. In cardiac muscle, a subpopulation of phospholemman with a unique phosphorylation…”
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Anti-Proliferative Actions of T-Type Calcium Channel Inhibition in Thy1 Nephritis by Cove-Smith, Andrea, Mulgrew, Christopher J, Rudyk, Olena, Dutt, Neelanjana, McLatchie, Linda M, Shattock, Michael J, Hendry, Bruce M

“…Aberrant proliferation of mesangial cells (MCs) is a key finding in progressive glomerular disease. TH1177 is a small molecule that has been shown to inhibit…”
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The amino terminus of receptor activity modifying proteins is a critical determinant of glycosylation state and ligand binding of calcitonin receptor-like receptor by Fraser, N J, Wise, A, Brown, J, McLatchie, L M, Main, M J, Foord, S M

“…The calcitonin receptor-like receptor (CRLR) can function as either a receptor for calcitonin gene-related peptide (CGRP) or for adrenomedullin (ADM),…”
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The rate of loss of T-tubules in cultured adult ventricular myocytes is species-dependent by Pavlovic, Davor, McLatchie, Linda M, Shattock, Michael J

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Capsaicin sensitivity is associated with the expression of the vanilloid (capsaicin) receptor (VR1) mRNA in adult rat sensory ganglia by Helliwell, Rachel J.A, McLatchie, Linda M, Clarke, Melanie, Winter, Janet, Bevan, Stuart, McIntyre, Peter

“…A vanilloid receptor (VR1) has recently been cloned and shown to be a target for capsaicin, the excitotoxic component of capsicum peppers (Caterina, M.J.,…”
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The phospholemman-induced modulation of Na/K ATPase Na affinity is dependent on intracellular calcium by McLatchie, Linda M, Berry, Roger G, Shattock, Michael J

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Nitric oxide-induced stimulation of the cardiac Na/K ATPase requires phospholemman by Hall, Andrew R, McLatchie, Linda M, Fuller, William, Shattock, Michael J

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Inhibition of human mesangial cell proliferation by targeting T-type calcium channels by Mulgrew, Christopher J, Cove-Smith, Andrea, McLatchie, Linda M, Brooks, Gavin, Shattock, Michael J, Hendry, Bruce M

“…Aberrant glomerular mesangial cell (MC) proliferation is a common finding in renal diseases. T-type calcium channels (T-CaCN) play an important role in the…”
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Regulation of ACh release from guinea pig bladder urothelial cells: potential role in bladder filling sensations by McLatchie, L M, Young, J S, Fry, C H

“…Background and Purpose The aim of this study was to quantify and characterize the mechanism of non‐neuronal ACh release from bladder urothelial cells and to…”
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A Separate Pool of Cardiac Phospholemman That Does Not Regulate or Associate with the Sodium Pump by Wypijewski, Krzysztof J., Howie, Jacqueline, Reilly, Louise, Tulloch, Lindsay B., Aughton, Karen L., McLatchie, Linda M., Shattock, Michael J., Calaghan, Sarah C., Fuller, William

“…Phospholemman (PLM), the principal quantitative sarcolemmal substrate for protein kinases A and C in the heart, regulates the cardiac sodium pump. Much like…”
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WITHDRAWN: The rate of loss of T-tubules in cultured adult ventricular myocytes is species-dependent by Pavlovic, Davor, McLatchie, Linda M., Shattock, Michael J.

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Abstract 1556: Esmolol As A Cardioplegic Agent; An Effect Beyond β-blockade by Fallouh, Hazem B, McLatchie, Linda M, Shattock, Michael J, Chambers, David J, Kentish, Jonathan C

“…Abstract only Esmolol, an ultra-short-acting β-blocker, is used in the treatment of hypertension and arrhythmias. We and others have shown that millimolar…”
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Phosphorylation state of phospholemman at serine 68 regulates Na/K ATPase activity by Pavlovic, Davor, McLatchie, Linda M., Shattock, Michael J., Fuller, William

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