Search Results - "McLachlan, Emma"
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Therapeutic window of dopamine D2/3 receptor occupancy to treat psychosis in Alzheimer's disease
Published in Brain (London, England : 1878) (01-04-2017)“…See Caravaggio and Graff-Guerrero (doi:10.1093/awx023) for a scientific commentary on this article.Antipsychotic drugs, originally developed to treat…”
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Journal Article -
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Misidentification Subtype of Alzheimer's Disease Psychosis Predicts a Faster Cognitive Decline
Published in CPT: pharmacometrics and systems pharmacology (01-05-2019)“…The presence of psychosis is associated with a more rapid decline in Alzheimer's disease (AD), but the impact of paranoid (persecutory delusions) and…”
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Reduced parahippocampal volume and psychosis symptoms in Alzheimer's disease
Published in International journal of geriatric psychiatry (01-02-2018)“…Objective Establishing structural imaging correlates of psychosis symptoms in Alzheimer's disease (AD) could localise pathology and target symptomatic…”
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Increased memory confidence and delusions in Alzheimer’s disease: a preliminary study
Published in Neurocase (08-11-2024)“…There is uncertainty about whether delusion formation in Alzheimer's disease (AD) can be explained by false memories. "Metamemory," the ability to…”
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False Memory and Delusions in Alzheimer's Disease
Published 01-01-2022“…Aims: This thesis aimed to investigate the relationship between memory errors and delusions in Alzheimer's disease (AD), in order to further elucidate the…”
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Dissertation -
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Neuroimaging correlates of false memory in 'Alzheimer's disease: A preliminary systematic review
Published in Psychiatry research. Neuroimaging (29-02-2020)“…•Few studies assess neuroimaging correlates of false memory in 'Alzheimer's disease.•There is significant heterogeneity in methodology of these studies.•Medial…”
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Phenomenological analysis of patient experiences of medical student teaching encounters
Published in Medical education (01-10-2012)“…Medical Education 2012: 46: 963–973 Context It is important to know how patients are affected by becoming opportunistically involved in medical student…”
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Therapeutic D2/3 receptor occupancies and response with low amisulpride blood concentrations in very late‐onset schizophrenia‐like psychosis (VLOSLP)
Published in International journal of geriatric psychiatry (01-02-2018)“…Objective Antipsychotic drug sensitivity in very late‐onset schizophrenia‐like psychosis (VLOSLP) is well documented, but poorly understood. This study aimed…”
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Journal Article -
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A population approach to characterise amisulpride pharmacokinetics in older people and Alzheimer’s disease
Published in Psychopharmacology (01-09-2016)“…Introduction Current prescribing guidelines for the antipsychotic amisulpride are based largely on pharmacokinetic (PK) studies in young adults, and there is a…”
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Association Between False Memories and Delusions in Alzheimer Disease
Published in JAMA psychiatry (Chicago, Ill.) (01-07-2023)“…Understanding the mechanisms of delusion formation in Alzheimer disease (AD) could inform the development of therapeutic interventions. It has been suggested…”
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Journal Article -
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A Population Approach to Guide Amisulpride Dose Adjustments in Older Patients With Alzheimer's Disease
Published in The journal of clinical psychiatry (01-07-2017)“…We have previously reported high dopamine D2/3 receptor occupancies at low amisulpride concentrations in older people with Alzheimer's disease (AD), during…”
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Assessing Model Uncertainty of Bioaccumulation Models by Combining Chemical Space Visualization with a Process-Based Diagnostic Approach
Published in Environmental science & technology (01-10-2011)“…As models describing human exposure to organic chemicals gain wider use in chemical risk assessment and management, it becomes important to understand their…”
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Journal Article -
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Music and health. Phenomenological investigation of a medical humanity
Published in Advances in health sciences education : theory and practice (01-05-2013)“…In response to the tendency for music to be under-represented in the discourse of medical humanities, we framed the question ‘how can music heal?’ We answered…”
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Journal Article -
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Depression Associated with Chronic Illness
Published in InnovAiT (01-05-2011)“…As the population ages, increasing numbers of patients regularly attend their GP with chronic conditions, such as diabetes, ischaemic heart disease,…”
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Book Review: Name of book: A Career Companion to Becoming a GP
Published in InnovAiT (01-07-2013)Get full text
Book Review