Search Results - "McLachlan, Donald R. C."

Aluminum in Neurological and Neurodegenerative Disease by McLachlan, Donald R C, Bergeron, Catherine, Alexandrov, Peter N, Walsh, William J, Pogue, Aileen I, Percy, Maire E, Kruck, Theodore P A, Fang, Zhide, Sharfman, Nathan M, Jaber, Vivian, Zhao, Yuhai, Li, Wenhong, Lukiw, Walter J

“…With continuing cooperation from 18 domestic and international brain banks over the last 36 years, we have analyzed the aluminum content of the temporal lobe…”
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Retraction Note: Aluminum in Neurological and Neurodegenerative Disease by McLachlan, Donald R. C., Bergeron, Catherine, Alexandrov, Peter N., Walsh, William J., Pogue, Aileen I., Percy, Maire E., Kruck, Theodore P. A., Fang, Zhide, Sharfman, Nathan M., Jaber, Vivian, Zhao, Yuhai, Li, Wenhong, Lukiw, Walter J.

“…The Editor-in Chief of Molecular Neurobiology has retracted this article [1] at the request of the corresponding author. This is because it significantly…”
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Run-on gene transcription in human neocortical nuclei. Inhibition by nanomolar aluminum and implications for neurodegenerative disease by Lukiw, W J, LeBlanc, H J, Carver, L A, McLachlan, D R, Bazan, N G

“…The incorporation of [alpha-32P]-uridine triphosphate into DNA transcription products was examined in short post-mortem interval (PMI) human brain neocortical…”
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RETRACTED ARTICLE: Aluminum in Neurological and Neurodegenerative Disease by McLachlan, Donald R. C., Bergeron, Catherine, Alexandrov, Peter N., Walsh, William J., Pogue, Aileen I., Percy, Maire E., Kruck, Theodore P. A., Fang, Zhide, Sharfman, Nathan M., Jaber, Vivian, Zhao, Yuhai, Li, Wenhong, Lukiw, Walter J.

“…With continuing cooperation from 18 domestic and international brain banks over the last 36 years, we have analyzed the aluminum content of the temporal lobe…”
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Localization of a new ferritin heavy chain sequence present in human brain mRNA to chromosome 11 by Percy, M E, Bauer, S J, Rainey, S, McLachlan, D R, Dhar, M S, Joshi, J G

“…Two types of ferritin heavy (H) chain clones have been isolated from cDNA libraries of human fetal and adult brain: one corresponds to the ferritin H chain…”
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Age-associated chromosome 21 loss in Down syndrome: possible relevance to mosaicism and Alzheimer disease by Percy, M E, Markovic, V D, Dalton, A J, McLachlan, D R, Berg, J M, Rusk, A C, Somerville, M J, Chodakowski, B, Andrews, D F

“…We previously observed low level mosaicism (2-4% normal cells) in phytohemagglutinin-stimulated peripheral blood lymphocytes (PBL) in 29% of a small group of…”
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Can the controversy of the role of aluminum in Alzheimer's disease be resolved? What are the suggested approaches to this controversy and methodological issues to be considered? by Savory, J, Exley, C, Forbes, W F, Huang, Y, Joshi, J G, Kruck, T, McLachlan, D R, Wakayama, I

“…Aluminum (Al) is unquestionably neurotoxic in both experimental animals and certain human diseases. Minute quantities injected intracerebrally into rabbits…”
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A predictor for side effects in patients with Alzheimer's disease treated with deferoxamine mesylate by Kruck, T P, Fisher, E A, McLachlan, D R

“…In a previously reported clinical trial, patients with Alzheimer's disease were treated with deferoxamine mesylate, which resulted in a 50% reduction in the…”
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Suppression of deferoxamine mesylate treatment-induced side effects by coadministration of isoniazid in a patient with Alzheimer's disease subject to aluminum removal by ionspecific chelation by Kruck, T P, Fisher, E A, McLachlan, D R

“…Deferoxamine treatment may produce serious side effects that can be eliminated by modification of treatment and by control of deferoxamine metabolism. A…”
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Issues of lead toxicity by Nicholls, D M, McLachlan, D R

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Family with 22-derived marker chromosome and late-onset dementia of the Alzheimer type: II. Further cytogenetic analysis of the marker and characterization of the high-level repeat sequences using fluorescence in situ hybridization by Percy, M E, Dearie, T G, Jabs, E W, Bauer, S J, Chodakowski, B, Somerville, M J, Lennox, A, McLachlan, D R, Baldini, A, Miller, D A

“…We have further characterized an unusual 22p+ marker chromosome with a double nucleolus organizer region (dNOR) previously identified in a family with…”
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