Search Results - "McLachlan, C. R"

Effects of cannabis on lung function: a population-based cohort study by Hancox, R. J, Poulton, R, Ely, M, Welch, D, Taylor, D. R, McLachlan, C. R, Greene, J. M, Moffitt, T. E, Caspi, A, Sears, M. R

“…The effects of cannabis on lung function remain unclear and may be different from those of tobacco. We compared the associations between use of these…”
Get full text

Associations between birth weight, early childhood weight gain and adult lung function by Hancox, R J, Poulton, R, Greene, J M, McLachlan, C R, Pearce, M S, Sears, M R

“…Low birth weight is associated with lower values for spirometry in adults but it is not known if birth weight influences other measures of pulmonary function…”
Get more information

Exhaled NO and assessment of anti-inflammatory effects of inhaled steroid: dose-response relationship by Jones, S.L, Herbison, P, Cowan, J.O, Flannery, E.M, Hancox, R.J, McLachlan, C.R, Taylor, D.R

“…Exhaled nitric oxide (eNO) is an easily measured marker of airway inflammation. This study was undertaken to evaluate the usefulness of serial eNO in…”
Get full text

Tolerance to beta-agonists during acute bronchoconstriction by Hancox, RJ, Aldridge, RE, Cowan, JO, Flannery, EM, Herbison, GP, McLachlan, CR, Town, GI, Taylor, DR

“…Previous reports suggest that regular use of β‐agonists does not lead to tolerance to their bronchodilator effects. However, most studies have been conducted…”
Get full text

Bronchodilator tolerance and rebound bronchoconstriction during regular inhaled β -agonist treatment by HANCOX, R.J., COWAN, J.O., FLANNERY, E.M., HERBISON, G.P., MCLACHLAN, C.R., TAYLOR, D.R.

“…There is uncertainty about the development of airway tolerance to β -agonists and the phenomenon of rebound bronchoconstriction on β -agonist withdrawal. We…”
Get full text

Randomised trial of an inhaled β2 agonist, inhaled corticosteroid and their combination in the treatment of asthma by Hancox, R J, Cowan, J O, Flannery, E M, Herbison, G P, McLachlan, C R, Wong, C S, Taylor, D R

“…BACKGROUND Although many asthmatic patients are treated with a combination of β2 agonist and corticosteroid inhalers, the clinical effects of combining the…”
Get full text

Aluminum in Neurological and Neurodegenerative Disease by McLachlan, Donald R C, Bergeron, Catherine, Alexandrov, Peter N, Walsh, William J, Pogue, Aileen I, Percy, Maire E, Kruck, Theodore P A, Fang, Zhide, Sharfman, Nathan M, Jaber, Vivian, Zhao, Yuhai, Li, Wenhong, Lukiw, Walter J

“…With continuing cooperation from 18 domestic and international brain banks over the last 36 years, we have analyzed the aluminum content of the temporal lobe…”
Get full text

The Predictive Value of Exhaled Nitric Oxide Measurements in Assessing Changes in Asthma Control by JONES, STUART L, KITTELSON, JOHN, COWAN, JAN O, FLANNERY, ERIN M, HANCOX, ROBERT J, MCLACHLAN, CHRISTENE R, TAYLOR, D. ROBIN

“…Exhaled nitric oxide (eNO) levels are increased in untreated or unstable asthma and measurements can be made easily. Our aim was to assess the usefulness of…”
Get full text

Relationship between socioeconomic status and asthma: a longitudinal cohort study by Hancox, R J, Milne, B J, Taylor, D R, Greene, J M, Cowan, J O, Flannery, E M, Herbison, G P, McLachlan, C R, Poulton, R, Sears, M R

“…Background: There is conflicting information about the relationship between asthma and socioeconomic status, with different studies reporting no, positive, or…”
Get full text

Retraction Note: Aluminum in Neurological and Neurodegenerative Disease by McLachlan, Donald R. C., Bergeron, Catherine, Alexandrov, Peter N., Walsh, William J., Pogue, Aileen I., Percy, Maire E., Kruck, Theodore P. A., Fang, Zhide, Sharfman, Nathan M., Jaber, Vivian, Zhao, Yuhai, Li, Wenhong, Lukiw, Walter J.

“…The Editor-in Chief of Molecular Neurobiology has retracted this article [1] at the request of the corresponding author. This is because it significantly…”
Get full text

Run-on gene transcription in human neocortical nuclei. Inhibition by nanomolar aluminum and implications for neurodegenerative disease by Lukiw, W J, LeBlanc, H J, Carver, L A, McLachlan, D R, Bazan, N G

“…The incorporation of [alpha-32P]-uridine triphosphate into DNA transcription products was examined in short post-mortem interval (PMI) human brain neocortical…”
Get full text

The Influence of Polymorphism at Position 16 of the β2-Adrenoceptor on the Development of Tolerance to β-Agonist by Taylor, D. R., Hancox, R. J., McRae, W., Cowan, J. O., Flannery, E. M., McLachlan, C. R., Herbison, G. P.

“…Polymorphism at position 16 of the β2-adrenoceptor alters receptor down-regulation in vitro. Our aim was to compare the development of tolerance to (3-agonist…”
Get full text

Systemic inflammation and lung function in young adults by Hancox, Robert J, Poulton, Richie, Greene, Justina M, Filsell, Susan, McLachlan, Christene R, Rasmussen, Finn, Taylor, D Robin, Williams, Michael J A, Williamson, Avis, Sears, Malcolm R

“…Background:Impaired lung function is associated with systemic inflammation and is a risk factor for cardiovascular disease in older adults. It is unknown when…”
Get full text

Can the controversy of the role of aluminum in Alzheimer's disease be resolved? What are the suggested approaches to this controversy and methodological issues to be considered? by Savory, J, Exley, C, Forbes, W F, Huang, Y, Joshi, J G, Kruck, T, McLachlan, D R, Wakayama, I

“…Aluminum (Al) is unquestionably neurotoxic in both experimental animals and certain human diseases. Minute quantities injected intracerebrally into rabbits…”
Get more information

House dust mite allergen levels in university student accommodation in Dunedin by McRae, Wendy M

“…Quantifies the levels of Dermatophagoides pteronyssinus in different university student accommodation in Dunedin, and assesses relationships with housing…”
Get full text

Further thoughts on the aluminum-Alzheimer's disease link by Forbes, W F, McLachlan, D R

“…STUDY OBJECTIVE AND METHOD: The results of studies on aluminum (Al) and Alzheimer's disease (AD) from groups in Newcastle, UK and Ontario, Canada were compared…”
Get full text

A 20b clockless DAC with sub-ppm-linearity 7.5nV/vHz-noise and 0.05ppm/°C-stability by McLachlan, R. C., Gillespie, A., Coln, M. C. W., Chisholm, D., Lee, D. T.

“…DACs without continuous clocking are often favored in applications such as medical imaging and scientific instrumentation. The DACs in these high-precision…”
Get full text

RETRACTED ARTICLE: Aluminum in Neurological and Neurodegenerative Disease by McLachlan, Donald R. C., Bergeron, Catherine, Alexandrov, Peter N., Walsh, William J., Pogue, Aileen I., Percy, Maire E., Kruck, Theodore P. A., Fang, Zhide, Sharfman, Nathan M., Jaber, Vivian, Zhao, Yuhai, Li, Wenhong, Lukiw, Walter J.

“…With continuing cooperation from 18 domestic and international brain banks over the last 36 years, we have analyzed the aluminum content of the temporal lobe…”
Get full text

Sex Differences in the Relation between Body Mass Index and Asthma and Atopy in a Birth Cohort by Hancox, Robert J, Milne, Barry J, Poulton, Richie, Taylor, D. Robin, Greene, Justina M, McLachlan, Christene R, Cowan, Jan O, Flannery, Erin M, Herbison, G. Peter, Sears, Malcolm R

“…Several studies have identified an association between asthma and obesity in women. It remains unclear if this association is due to genuine asthma or to…”
Get full text

Age-associated chromosome 21 loss in Down syndrome: possible relevance to mosaicism and Alzheimer disease by Percy, M E, Markovic, V D, Dalton, A J, McLachlan, D R, Berg, J M, Rusk, A C, Somerville, M J, Chodakowski, B, Andrews, D F

“…We previously observed low level mosaicism (2-4% normal cells) in phytohemagglutinin-stimulated peripheral blood lymphocytes (PBL) in 29% of a small group of…”
Get more information