Search Results - "McKnite, Autumn"

Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits by McKnite, Autumn M, Perez-Munoz, Maria Elisa, Lu, Lu, Williams, Evan G, Brewer, Simon, Andreux, Pénélope A, Bastiaansen, John W M, Wang, Xusheng, Kachman, Stephen D, Auwerx, Johan, Williams, Robert W, Benson, Andrew K, Peterson, Daniel A, Ciobanu, Daniel C

“…The gastrointestinal tract harbors a complex and diverse microbiota that has an important role in host metabolism. Microbial diversity is influenced by a…”
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BMP7 functions predominantly as a heterodimer with BMP2 or BMP4 during mammalian embryogenesis by Kim, Hyung-Seok, Neugebauer, Judith, McKnite, Autumn, Tilak, Anup, Christian, Jan L

“…BMP7/BMP2 or BMP7/BMP4 heterodimers are more active than homodimers in vitro, but it is not known whether these heterodimers signal in vivo. To test this, we…”
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Drug exposure during pregnancy: Current understanding and approaches to measure maternal-fetal drug exposure by Hudson, Rachel E, Metz, Torri D, Ward, Robert M, McKnite, Autumn M, Enioutina, Elena Y, Sherwin, Catherine M, Watt, Kevin M, Job, Kathleen M

“…Prescription drug use is prevalent during pregnancy, yet there is limited knowledge about maternal-fetal safety and efficacy of this drug use because pregnant…”
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Medication patterns and dosing guidance in pediatric patients supported with intermittent hemodialysis or continuous kidney replacement therapy by McKnite, Autumn M., Green, Danielle J., Nelson, Raoul, Brewer, Simon C., Watt, Kevin M.

“…Background Hemodialysis is a life-saving technology used during periods of acute or chronic kidney failure to remove toxins, and maintain fluid, electrolyte…”
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Diet modulates cecum bacterial diversity and physiological phenotypes across the BXD mouse genetic reference population by Perez-Munoz, Maria Elisa, McKnite, Autumn M, Williams, Evan G, Auwerx, Johan, Williams, Robert W, Peterson, Daniel A, Ciobanu, Daniel C

“…The BXD family has become one of the preeminent genetic reference populations to understand the genetic and environmental control of phenotypic variation. Here…”
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Interaction of ceftazidime and clindamycin with extracorporeal life support by Hunt, J. Porter, McKnite, Autumn M., Green, Danielle J., Whelan, Aviva J., Imburgia, Carina E., Watt, Kevin M.

“…Ceftazidime and clindamycin are commonly prescribed to critically ill patients who require extracorporeal life support such as ECMO and CRRT. The effect of…”
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Amiodarone extraction by continuous renal replacement therapy: results from an ex vivo study by Green, Danielle J, McKnite, Autumn M, Hunt, J Porter, Imburgia, Carina E, Kelley, Walter, Watt, Kevin M

“…Continuous renal replacement therapy (CRRT) is a lifesaving therapy for critically ill patients with acute renal failure. Some patients supported with CRRT…”
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Extraction of ketamine and dexmedetomidine by extracorporeal life support circuits by Chevalier, Andrew, Porter Hunt, J, Whelan, Aviva, McKnite, Autumn, Watt, Kevin M, Green, Danielle J

“…Patients supported with extracorporeal life support (ECLS) circuits such as ECMO and CRRT often require high doses of sedatives and analgesics, including…”
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A physiologically‐based pharmacokinetic modeling approach for dosing amiodarone in children on ECMO by Yellepeddi, Venkata K., Hunt, John Porter, Green, Danielle J., McKnite, Autumn, Whelan, Aviva, Watt, Kevin

“…Extracorporeal membrane oxygenation (ECMO) is a cardiopulmonary bypass device commonly used to treat cardiac arrest in children. The American Heart Association…”
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Remdesivir and GS-441524 Extraction by Ex Vivo Extracorporeal Life Support Circuits by Imburgia, Carina E., Rower, Joseph E., Green, Danielle J., Mcknite, Autumn M., Kelley, Walter E., Reilly, Christopher A., Watt, Kevin M.

“…Patients with severe, COVID-related multi-organ failure often require extracorporeal life support (ECLS) such as extracorporeal membrane oxygenation (ECMO) or…”
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Maximum likelihood estimation of renal transporter ontogeny profiles for pediatric PBPK modeling by Hunt, J. Porter, Dubinsky, Samuel, McKnite, Autumn M., Cheung, Kit Wun Kathy, Groen, Bianca D., Giacomini, Kathleen M., Wildt, Saskia N., Edginton, Andrea N., Watt, Kevin M.

“…Optimal treatment of infants with many renally cleared drugs must account for maturational differences in renal transporter (RT) activity. Pediatric…”
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Meropenem extraction by ex vivo extracorporeal life support circuits by Honeycutt, Christopher Cole, McDaniel, Charles Griffin, McKnite, Autumn, Hunt, J Porter, Whelan, Aviva, Green, Danielle J, Watt, Kevin M

“…Meropenem is a broad-spectrum carbapenem-type antibiotic commonly used to treat critically ill patients infected with extended-spectrum β-lactamase…”
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Anakinra Removal by Continuous Renal Replacement Therapy: An Ex Vivo Analysis by Dubinsky, Samuel D J, Watt, Kevin M, Imburgia, Carina E, Mcknite, Autumn M, Hunt, J Porter, Rice, Cassandra, Rower, Joseph E, Edginton, Andrea N

“…Patients with sepsis are at significant risk for multiple organ dysfunction, including the lungs and kidneys. To manage the morbidity associated with kidney…”
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Medication based machine learning to identify subpopulations of pediatric hemodialysis patients in an electronic health record database by McKnite, Autumn M., Job, Kathleen M., Nelson, Raoul, Sherwin, Catherine M.T., Watt, Kevin M., Brewer, Simon C.

“…Electronic health records (EHRs) have given rise to large and complex databases of medical information that have the potential to become powerful tools for…”
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Variation in time and magnitude of immune response and viremia in experimental challenges with Porcine circovirus 2b by Engle, Taylor B, Jobman, Erin E, Moural, Timothy W, McKnite, Autumn M, Bundy, Justin W, Barnes, Sarah Y, Davis, Emily H, Galeota, Judith A, Burkey, Thomas E, Plastow, Graham S, Kachman, Stephen D, Ciobanu, Daniel C

“…BACKGROUND: Porcine circovirus 2 is the primary agent responsible for inducing a group of associated diseases known as Porcine Circovirus Associated Diseases…”
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Genotypes of Brassica rapa respond differently to plant-induced variation in air CO₂ concentration in growth chambers with standard and enhanced venting by Edwards, Christine E, Haselhorst, Monia S. H, McKnite, Autumn M, Ewers, Brent E, Williams, David G, Weinig, Cynthia

“…Growth chambers allow measurement of phenotypic differences among genotypes under controlled environment conditions. However, unintended variation in growth…”
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25: KETAMINE EXTRACTION BY EXTRACORPOREAL LIFE SUPPORT CIRCUITS by Chevalier, Andrew, Green, Danielle, Hudson, Rachel, Porter Hunt, J., McKnite, Autumn, Whelan, Aviva, Watt, Kevin

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872: REMDESIVIR EXTRACTION BY EXTRACORPOREAL LIFE SUPPORT CIRCUITS by Green, Danielle, Imburgia, Carina, Rower, Joseph, McKnite, Autumn, Kelley, Walter, Reilly, Christopher, Watt, Kevin

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Lack of evidence that fibrillin1 regulates bone morphogenetic protein 4 activity in kidney or lung by McKnite, Autumn, Kim, Hyung‐Seok, Silva, Joshua, Christian, Jan L.

“…Background The Bone morphogenetic protein 4 (BMP4) precursor protein is cleaved at two sites to generate an active ligand and inactive prodomain. The ligand…”
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Physiologically Based Pharmacokinetic Modelling in Critically Ill Children Receiving Anakinra While on Extracorporeal Life Support by Dubinsky, Samuel, Hamadeh, Abdullah, Imburgia, Carina, McKnite, Autumn, Porter Hunt, J., Wong, Kristy, Rice, Cassandra, Rower, Joseph, Watt, Kevin, Edginton, Andrea

“…Background and Objective Because of the pathophysiological changes associated with critical illness and the use of extracorporeal life support (ECLS) such as…”
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