Search Results - "McKnight, C J"
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Cardiorespiratory coupling in the bottlenose dolphin (Tursiops truncatus)
Published in Frontiers in physiology (21-09-2023)“…Introduction: The bottlenose dolphin ( Tursiops truncatus ) is an intermittent breather, where the breath begins with an exhalation followed by inhalation and…”
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2
Evolution of a Protein Fold In vitro
Published in Science (American Association for the Advancement of Science) (09-04-1999)“…A "switch" mutant of the Arc repressor homodimer was constructed by interchanging the sequence positions of a hydrophobic core residue, leucine 12, and an…”
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Sequence-Specific DNA Binding by a Short Peptide Dimer
Published in Science (American Association for the Advancement of Science) (17-08-1990)“…A recently described class of DNA binding proteins is characterized by the "bZIP" motif, which consists of a basic region that contacts DNA and an adjacent…”
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NMR structure of the 35-residue villin headpiece subdomain
Published in Nature structural biology (01-03-1997)“…The NMR structure of an autonomously folding subdomain from villin headpiece is reported. It forms a novel three helix structure with the actin-binding…”
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Functional and Nonfunctional LamB Signal Sequences Can Be Distinguished by Their Biophysical Properties
Published in The Journal of biological chemistry (15-10-1989)“…The roles of the signal sequence in the secretion of proteins remain unclear despite extensive research. We have examined properties of synthetic peptides…”
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Minimum length of a sequence-specific DNA binding peptide
Published in Biochemistry (Easton) (04-08-1992)“…NMR experiments show that a stable complex can be formed between a 14-base-pair oligonucleotide and a disulfide-bonded dimer of a peptide containing 27…”
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Conformational and Membrane-Binding Properties of a Signal Sequence are Largely Unaltered by Its Adjacent Mature Region
Published in Proceedings of the National Academy of Sciences - PNAS (01-07-1991)“…We have synthesized a peptide corresponding to the 25-residue signal sequence plus the first 28 residues of the Escherichia coli outer membrane protein LamB in…”
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Fluorescence analysis of tryptophan-containing variants of the LamB signal sequence upon insertion into a lipid bilayer
Published in Biochemistry (Easton) (01-06-1991)“…To investigate the interaction of the LamB signal sequence with lipid bilayers, we have synthesized three tryptophan-containing analogues of the wild-type…”
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A Novel Nontruncating APOB Gene Mutation, R463W, Causes Familial Hypobetalipoproteinemia
Published in The Journal of biological chemistry (11-04-2003)“…Familial hypobetalipoproteinemia (FHBL), an autosomal co-dominant disorder, is associated with reduced plasma concentrations (<5th percentile for age and sex)…”
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10
A Thermostable 35-Residue Subdomain within Villin Headpiece
Published in Journal of molecular biology (12-07-1996)“…The actin-bundling protein villin contains, at its extreme C terminus, a compact f-actin binding domain called “headpiece”. This 76-amino acid domain from…”
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An evolutionary bridge to a new protein fold
Published in Nature structural biology (01-12-2000)“…Arc repressor bearing the N11L substitution (Arc-N11L) is an evolutionary intermediate between the wild type protein, in which the region surrounding position…”
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Autonomy and the akratic patient
Published in Journal of medical ethics (01-03-1994)Get full text
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Autonomy and the akratic patient
Published in Journal of medical ethics (01-12-1993)“…I argue that the distinction which is current in much writing on medical ethics between autonomous and non-autonomous patients cannot cope comfortably with…”
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14
Zinc and copper bind to unique sites of histatin 5
Published in FEBS letters (23-02-2001)“…Metal binding has been suggested to be relevant in the antifungal and antibacterial mechanism of histatin 5, a human salivary protein. Proton nuclear magnetic…”
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NMR structure of an F-actin-binding “headpiece” motif from villin
Published in Journal of molecular biology (17-12-1999)“…A growing family of F-actin-bundling proteins harbors a modular F-actin-binding headpiece domain at the C terminus. Headpiece provides one of the two…”
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Villin-type headpiece domains show a wide range of F-actin-binding affinities
Published in Cell motility and the cytoskeleton (01-05-2002)“…The villin‐type “headpiece” domain is a modular motif found at the extreme C‐terminus of larger “core” domains in over 25 cytoskeletal proteins in plants and…”
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The N-terminal 17% of apoB binds tightly and irreversibly to emulsions modeling nascent very low density lipoproteins
Published in Journal of lipid research (01-01-2001)“…The N-terminal 17% of apolipoprotein B (apoB-17) readily associates with dimyristoylphosphatidylcholine (DMPC) multilamellar vesicles (MLV) to form large…”
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The Survival of the Survival Lottery
Published in Journal of applied philosophy (01-04-1996)“…In his paper 'The Survival Lottery' John Harris suggested that there could be situations where the rational thing to do would be to kill a healthy person and…”
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Using the manual alphabet in teaching reading to learning disabled children
Published in Journal of learning disabilities (01-11-1979)Get more information
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Helix formation and stability in a signal sequence
Published in Biochemistry (Easton) (17-10-1989)“…A detailed nuclear magnetic resonance analysis of the isolated LamB signal peptide (MMITLRKLPLAVAVAAGVMSAQAMA) under conditions defined by circular dichroism…”
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