Search Results - "McKinnon, Karen"

Internal Variability and Regional Climate Trends in an Observational Large Ensemble by McKinnon, Karen A., Deser, Clara

“…Recent observed climate trends result from a combination of external radiative forcing and internally generated variability. To better contextualize these…”
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How Unexpected Was the 2021 Pacific Northwest Heatwave? by McKinnon, Karen A., Simpson, Isla R.

“…The 2021 Pacific Northwest heatwave featured record‐smashing high temperatures, raising questions about whether extremes are changing faster than the mean, and…”
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Hot extremes have become drier in the United States Southwest by McKinnon, Karen A., Poppick, Andrew, Simpson, Isla R.

“…The impacts of summer heat extremes are mediated by humidity. Increases in temperatures due to human-caused climate change are generally expected to increase…”
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The changing shape of Northern Hemisphere summer temperature distributions by McKinnon, Karen A., Rhines, Andrew, Tingley, Martin P., Huybers, Peter

“…The occurrence of recent summer temperature extremes in the midlatitudes has raised questions about whether and how the distributions of summer temperature are…”
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Observation-Based Simulations of Humidity and Temperature Using Quantile Regression by Poppick, Andrew, McKinnon, Karen A.

“…The human impacts of changes in heat events depend on changes in the joint behavior of temperature and humidity. Little is currently known about these complex…”
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Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy by Min, Yuanzeng, Roche, Kyle C., Tian, Shaomin, Eblan, Michael J., McKinnon, Karen P., Caster, Joseph M., Chai, Shengjie, Herring, Laura E., Zhang, Longzhen, Zhang, Tian, DeSimone, Joseph M., Tepper, Joel E., Vincent, Benjamin G., Serody, Jonathan S., Wang, Andrew Z.

“…Nanoparticles can be utilized to capture tumour antigens and improve their presentation, which in turn improves the efficacy of cancer immunotherapy…”
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Decadal predictability of late winter precipitation in western Europe through an ocean–jet stream connection by Simpson, Isla R., Yeager, Stephen G., McKinnon, Karen A., Deser, Clara

“…The characteristics of the North Atlantic jet stream play a key role in the weather and climate of western Europe. Although much of the year-to-year…”
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Observed humidity trends in dry regions contradict climate models by Simpson, Isla R, McKinnon, Karen A, Kennedy, Daniel, Lawrence, David M, Lehner, Flavio, Seager, Richard

“…Arid and semi-arid regions of the world are particularly vulnerable to greenhouse gas-driven hydroclimate change. Climate models are our primary tool for…”
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How Well Do We Know ENSO’s Climate Impacts over North America, and How Do We Evaluate Models Accordingly? by Deser, Clara, Simpson, Isla R., Phillips, Adam. S., McKinnon, Karen A.

“…The role of sampling variability in ENSO composites of winter surface air temperature and precipitation over North America during the period 1920–2013 is…”
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Seasonally Resolved Distributional Trends of North American Temperatures Show Contraction of Winter Variability by Rhines, Andrew, McKinnon, Karen A., Tingley, Martin P., Huybers, Peter

“…There is considerable interest in determining whether recent changes in the temperature distribution extend beyond simple shifts in the mean. The authors…”
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Modeled and Observed Multidecadal Variability in the North Atlantic Jet Stream and Its Connection to Sea Surface Temperatures by Simpson, Isla R., Deser, Clara, McKinnon, Karen A., Barnes, Elizabeth A.

“…Multidecadal variability in the North Atlantic jet stream in general circulation models (GCMs) is compared with that in reanalysis products of the twentieth…”
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Estimating Changes in the Observed Relationship Between Humidity and Temperature Using Noncrossing Quantile Smoothing Splines by McKinnon, Karen A., Poppick, Andrew

“…The impacts of warm season heat extremes are dependent on both temperature and humidity, so it is critical to properly model their relationship, including how…”
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The pace of change of summertime temperature extremes by McKinnon, Karen A, Simpson, Isla R, Williams, A Park

“…Summer temperature extremes can have large impacts on humans and the biosphere, and an increase in heat extremes is one of the most visible symptoms of climate…”
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Cooling of US Midwest summer temperature extremes from cropland intensification by Mueller, Nathaniel D., Butler, Ethan E., McKinnon, Karen A., Rhines, Andrew, Tingley, Martin, Holbrook, N. Michele, Huybers, Peter

“…High temperature extremes during the growing season can reduce agricultural production. At the same time, agricultural practices can modify temperatures by…”
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Growing Impact of Wildfire on Western US Water Supply by Williams, A Park, Livneh, Ben, McKinnon, Karen A, Hansen, Winslow D, Mankin, Justin S, Cook, Benjamin I, Smerdon, Jason E, Varuolo-Clarke, Arianna M, Bjarke, Nels R, Juang, Caroline S, Lettenmaier, Dennis P

“…Streamflow often increases after fire, but the persistence of this effect and its importance to present and future regional water resources are unclear. This…”
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How Exceptional Was the 2015–2019 Central American Drought? by Anderson, Talia G., McKinnon, Karen A., Pons, Diego, Anchukaitis, Kevin J.

“…The Central American Dry Corridor experienced five consecutive years of drought from 2015 to 2019. Here, we find that the severity of this drought was driven…”
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The Value of Initial Condition Large Ensembles to Robust Adaptation Decision‐Making by Mankin, Justin S., Lehner, Flavio, Coats, Sloan, McKinnon, Karen A.

“…The origins of uncertainty in climate projections have major consequences for the scientific and policy decisions made in response to climate change. Internal…”
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Treg depletion potentiates checkpoint inhibition in claudin-low breast cancer by Taylor, Nicholas A, Vick, Sarah C, Iglesia, Michael D, Brickey, W June, Midkiff, Bentley R, McKinnon, Karen P, Reisdorf, Shannon, Anders, Carey K, Carey, Lisa A, Parker, Joel S, Perou, Charles M, Vincent, Benjamin G, Serody, Jonathan S

“…Claudin-low breast cancer is an aggressive subtype that confers poor prognosis and is found largely within the clinical triple-negative group of breast cancer…”
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Emergent Constraints on the Large-Scale Atmospheric Circulation and Regional Hydroclimate: Do They Still Work in CMIP6 and How Much Can They Actually Constrain the Future? by Simpson, Isla R., McKinnon, Karen A., Davenport, Frances V., Tingley, Martin, Lehner, Flavio, Fahad, Abdullah Al, Chen, Di

“…An emergent constraint (EC) is a statistical relationship, across a model ensemble, between a measurable aspect of the present-day climate (the predictor) and…”
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Concurrent Definitive Immunoradiotherapy for Patients with Stage III-IV Head and Neck Cancer and Cisplatin Contraindication by Weiss, Jared, Sheth, Siddharth, Deal, Allison M, Grilley Olson, Juneko E, Patel, Samip, Hackman, Trevor G, Blumberg, Jeffrey M, Galloway, Thomas J, Patel, Shetal, Zanation, Adam M, Shen, Colette J, Hayes, D Neil, Hilliard, Christopher, Mehra, Ranee, McKinnon, Karen P, Wang, Hsing-Hui, Weissler, Mark Christian, Bauman, Jessica R, Chera, Bhishamjit S, Vincent, Benjamin G

“…Although cisplatin plus radiotherapy is a standard treatment of locally advanced head and neck squamous cell carcinoma (LA-HNSCC), cisplatin contraindication…”
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