Search Results - "McKinley, T"

Pathophysiology in patients with polytrauma by Pape, H.-C., Moore, E.E., McKinley, T., Sauaia, A.

“…The pathophysiology after polytrauma represents a complex network of interactions. While it was thought for a long time that the direct and indirect effects of…”
Get full text

In vivo imaging of cancer cell size and cellularity using temporal diffusion spectroscopy by Jiang, Xiaoyu, Li, Hua, Xie, Jingping, McKinley, Eliot T., Zhao, Ping, Gore, John C., Xu, Junzhong

“…Purpose A temporal diffusion MRI spectroscopy based approach has been developed to quantify cancer cell size and density in vivo. Methods A novel imaging…”
Get full text

Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation by Banerjee, Amrita, Herring, Charles A., Chen, Bob, Kim, Hyeyon, Simmons, Alan J., Southard-Smith, Austin N., Allaman, Margaret M., White, James R., Macedonia, Mary C., Mckinley, Eliot T., Ramirez-Solano, Marisol A., Scoville, Elizabeth A., Liu, Qi, Wilson, Keith T., Coffey, Robert J., Washington, M. Kay, Goettel, Jeremy A., Lau, Ken S.

“…Countries endemic for parasitic infestations have a lower incidence of Crohn’s disease (CD) than nonendemic countries, and there have been anecdotal reports of…”
Get full text

Transfer of Functional Cargo in Exomeres by Zhang, Qin, Higginbotham, James N., Jeppesen, Dennis K., Yang, Yu-Ping, Li, Wei, McKinley, Eliot T., Graves-Deal, Ramona, Ping, Jie, Britain, Colleen M., Dorsett, Kaitlyn A., Hartman, Celine L., Ford, David A., Allen, Ryan M., Vickers, Kasey C., Liu, Qi, Franklin, Jeffrey L., Bellis, Susan L., Coffey, Robert J.

“…Exomeres are a recently discovered type of extracellular nanoparticle with no known biological function. Herein, we describe a simple ultracentrifugation-based…”
Get full text

Magnetic resonance imaging of mean cell size in human breast tumors by Xu, Junzhong, Jiang, Xiaoyu, Li, Hua, Arlinghaus, Lori R., McKinley, Eliot T., Devan, Sean P., Hardy, Benjamin M., Xie, Jingping, Kang, Hakmook, Chakravarthy, A. Bapsi, Gore, John C.

“…Purpose Cell size is a fundamental characteristic of all tissues, and changes in cell size in cancer reflect tumor status and response to treatments, such as…”
Get full text

Limits of [18F]-FLT PET as a biomarker of proliferation in oncology by McKinley, Eliot T, Ayers, Gregory D, Smith, R Adam, Saleh, Samir A, Zhao, Ping, Washington, Mary Kay, Coffey, Robert J, Manning, H Charles

“…Non-invasive imaging biomarkers of cellular proliferation hold great promise for quantifying response to personalized medicine in oncology. An emerging…”
Get full text

In vivo magnetic resonance imaging of treatment-induced apoptosis by Jiang, Xiaoyu, McKinley, Eliot T., Xie, Jingping, Li, Hua, Xu, Junzhong, Gore, John C.

“…Imaging apoptosis could provide an early and specific means to monitor tumor responses to treatment. To date, despite numerous attempts to develop molecular…”
Get full text

Beneficial Effects of Breast Milk in the Neonatal Intensive Care Unit on the Developmental Outcome of Extremely Low Birth Weight Infants at 18 Months of Age by Vohr, Betty R, Poindexter, Brenda B, Dusick, Anna M, McKinley, Leslie T, Wright, Linda L, Langer, John C, Poole, W. Kenneth, NICHD Neonatal Research Network

“…Beneficial effects of breast milk on cognitive skills and behavior ratings have been demonstrated previously in term and very low birth weight infants…”
Get full text

A conceptual time window‐based model for the early stratification of trauma patients by Lamparello, A. J., Namas, R. A., Constantine, G., McKinley, T. O., Elster, E., Vodovotz, Y., Billiar, T. R.

“…Progress in the testing of therapies targeting the immune response following trauma, a leading cause of morbidity and mortality worldwide, has been slow. We…”
Get full text

Persistent Beneficial Effects of Breast Milk Ingested in the Neonatal Intensive Care Unit on Outcomes of Extremely Low Birth Weight Infants at 30 Months of Age by Vohr, Betty R, Poindexter, Brenda B, Dusick, Anna M, McKinley, Leslie T, Higgins, Rosemary D, Langer, John C, Poole, W. Kenneth, National Institute of Child Health and Human Development National Research Network

“…We previously reported beneficial effects of breast milk ingestion by infants with extremely low birth weight in the NICU on developmental outcomes at 18…”
Get full text

CAMKK2 is upregulated in primary human osteoarthritis and its inhibition protects against chondrocyte apoptosis by Dilley, J.E., Seetharam, A., Ding, X., Bello, M.A., Shutter, J., Burr, D.B., Natoli, R.M., McKinley, T.O., Sankar, U.

“…To investigate the role of calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) in human osteoarthritis. Paired osteochondral plugs and articular…”
Get full text

Rutting and rambling: Movement characteristics reveal partial migration in adult male white‐tailed deer at a latitude void of chronic and severe environmental fluctuations by Resop, Luke, Demarais, Stephen, Strickland, Bronson K., McKinley, William T., Street, Garrett

“…White‐tailed deer (Odocoileus virginianus) are generally considered a home‐ranging species, although northern populations may migrate between summer and winter…”
Get full text

Predicting chronic wasting disease in white-tailed deer at the county scale using machine learning by Ahmed, Md Sohel, Hanley, Brenda J., Mitchell, Corey I., Abbott, Rachel C., Hollingshead, Nicholas A., Booth, James G., Guinness, Joe, Jennelle, Christopher S., Hodel, Florian H., Gonzalez-Crespo, Carlos, Middaugh, Christopher R., Ballard, Jennifer R., Clemons, Bambi, Killmaster, Charlie H., Harms, Tyler M., Caudell, Joe N., Benavidez Westrich, Kathryn M., McCallen, Emily, Casey, Christine, O’Brien, Lindsey M., Trudeau, Jonathan K., Stewart, Chad, Carstensen, Michelle, McKinley, William T., Hynes, Kevin P., Stevens, Ashley E., Miller, Landon A., Cook, Merril, Myers, Ryan T., Shaw, Jonathan, Tonkovich, Michael J., Kelly, James D., Grove, Daniel M., Storm, Daniel J., Schuler, Krysten L.

“…Continued spread of chronic wasting disease (CWD) through wild cervid herds negatively impacts populations, erodes wildlife conservation, drains resource…”
Get full text

History matching of a complex epidemiological model of human immunodeficiency virus transmission by using variance emulation by Andrianakis, I., Vernon, I., McCreesh, N., McKinley, T. J., Oakley, J. E., Nsubuga, R. N., Goldstein, M., White, R. G.

“…Complex stochastic models are commonplace in epidemiology, but their utility depends on their calibration to empirical data. History matching is a…”
Get full text

Strain-dependent oxidant release in articular cartilage originates from mitochondria by Brouillette, M. J., Ramakrishnan, P. S., Wagner, V. M., Sauter, E. E., Journot, B. J., McKinley, T. O., Martin, J. A.

“…Mechanical loading is essential for articular cartilage homeostasis and plays a central role in the cartilage pathology, yet the mechanotransduction processes…”
Get full text

Avian coronavirus infectious bronchitis attenuated live vaccines undergo selection of subpopulations and mutations following vaccination by McKinley, Enid T, Hilt, Deborah A, Jackwood, Mark W

“…Summary In this study, we were interested in determining if high titered egg adapted modified live infectious bronchitis virus (IBV) vaccines contain spike…”
Get full text

Recombinant Limosilactobacillus (Lactobacillus) delivering nanobodies against Clostridium perfringens NetB and alpha toxin confers potential protection from necrotic enteritis by Gangaiah, Dharanesh, Ryan, Valerie, Van Hoesel, Daphne, Mane, Shrinivasrao P., Mckinley, Enid T., Lakshmanan, Nallakannu, Reddy, Nandakumar D., Dolk, Edward, Kumar, Arvind

“…Necrotic enteritis (NE), caused by Clostridium perfringens, is an intestinal disease with devastating economic losses to the poultry industry. NE is a complex…”
Get full text

Testing secondary sex ratio bias hypotheses in white‐tailed deer in Mississippi, USA by Dentinger, Jane E., Dolan Todt, Lacy A., Schultz, Emma A., Helferich, James N., Demarais, Stephen, DeYoung, Randy W., McKinley, William T., Strickland, Bronson K., Boudreau, Melanie R.

“…Natural selection favors individuals with the highest inclusive fitness (i.e., total number of descendants). In cases where one sex is more productive, one or…”
Get full text

Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps by Chen, Bob, Scurrah, Cherie’ R., McKinley, Eliot T., Simmons, Alan J., Ramirez-Solano, Marisol A., Zhu, Xiangzhu, Markham, Nicholas O., Heiser, Cody N., Vega, Paige N., Rolong, Andrea, Kim, Hyeyon, Sheng, Quanhu, Drewes, Julia L., Zhou, Yuan, Southard-Smith, Austin N., Xu, Yanwen, Ro, James, Jones, Angela L., Revetta, Frank, Berry, Lynne D., Niitsu, Hiroaki, Islam, Mirazul, Pelka, Karin, Hofree, Matan, Chen, Jonathan H., Sarkizova, Siranush, Ng, Kimmie, Giannakis, Marios, Boland, Genevieve M., Aguirre, Andrew J., Anderson, Ana C., Rozenblatt-Rosen, Orit, Regev, Aviv, Hacohen, Nir, Kawasaki, Kenta, Sato, Toshiro, Goettel, Jeremy A., Grady, William M., Zheng, Wei, Washington, M. Kay, Cai, Qiuyin, Sears, Cynthia L., Goldenring, James R., Franklin, Jeffrey L., Su, Timothy, Huh, Won Jae, Vandekar, Simon, Roland, Joseph T., Liu, Qi, Coffey, Robert J., Shrubsole, Martha J., Lau, Ken S.

“…Colorectal cancers (CRCs) arise from precursor polyps whose cellular origins, molecular heterogeneity, and immunogenic potential may reveal diagnostic and…”
Get full text

Synthesis and Structure–Activity Relationships of 5,6,7-Substituted Pyrazolopyrimidines: Discovery of a Novel TSPO PET Ligand for Cancer Imaging by Tang, Dewei, McKinley, Eliot T, Hight, Matthew R, Uddin, Md. Imam, Harp, Joel M, Fu, Allie, Nickels, Michael L, Buck, Jason R, Manning, H. Charles

“…Focused library synthesis and structure–activity relationship development of 5,6,7-substituted pyrazolopyrimidines led to the discovery of…”
Get full text