Search Results - "McKinley, J"

Unsupervised classification applications in enhancing lithological mapping and geological understanding: a case study from Northern Ireland by Smillie, Z., Demyanov, V., McKinley, J., Cooper, M.

“…Pattern classification algorithms can help us to recognize and predict patterns in large and complex multivariate datasets. Self-organizing maps (SOMs), which…”
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Dirichlet process mixture models to impute missing predictor data in counterfactual prediction models: an application to predict optimal type 2 diabetes therapy by Cardoso, Pedro, Dennis, John M, Bowden, Jack, Shields, Beverley M, McKinley, Trevelyan J

“…The handling of missing data is a challenge for inference and regression modelling. A particular challenge is dealing with missing predictor information,…”
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Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study by Karageorgiou, Vasilios, Casanova, Francesco, O'Loughlin, Jessica, Green, Harry, McKinley, Trevelyan J, Bowden, Jack, Tyrrell, Jessica

“…Background Major depressive disorder (MDD) has a significant impact on global burden of disease. Complications in clinical management can occur when response…”
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Bayesian history matching of complex infectious disease models using emulation: a tutorial and a case study on HIV in Uganda by Andrianakis, Ioannis, Vernon, Ian R, McCreesh, Nicky, McKinley, Trevelyan J, Oakley, Jeremy E, Nsubuga, Rebecca N, Goldstein, Michael, White, Richard G

“…Advances in scientific computing have allowed the development of complex models that are being routinely applied to problems in disease epidemiology, public…”
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The use of geoscience methods for terrestrial forensic searches by Pringle, J.K., Ruffell, A., Jervis, J.R., Donnelly, L., McKinley, J., Hansen, J., Morgan, R., Pirrie, D., Harrison, M.

“…Geoscience methods are increasingly being utilised in criminal, environmental and humanitarian forensic investigations, and the use of such methods is…”
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Anti-inflammatory reflex action of splanchnic sympathetic nerves is distributed across abdominal organs by Martelli, Davide, Farmer, David G S, McKinley, Michael J, Yao, Song T, McAllen, Robin M

“…The splanchnic anti-inflammatory pathway has been proposed as the efferent arm of the inflammatory reflex. Although much evidence points to the spleen as the…”
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A nose for trouble: ecotoxicological implications for climate change and disease in Saiga antelope (S. t. tatarica) by Mullineaux, S. T., McKinley, J. M., Marks, N. J., Doherty, R., Scantlebury, D. M.

“…In recent decades, Saiga antelope ( Saiga t. tatarica ) mass die-offs have become more common. The mass die-off of 2015 in central Kazakhstan, recorded 140,000…”
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Sex differences in fat taste responsiveness are modulated by estradiol by Dahir, Naima S, Calder, Ashley N, McKinley, Blake J, Liu, Yan, Gilbertson, Timothy A

“…Sex as a biological variable has been the focus of increasing interest. Relatively few studies have focused, however, on differences in peripheral taste…”
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From sensory circumventricular organs to cerebral cortex: Neural pathways controlling thirst and hunger by McKinley, Michael J., Denton, Derek A., Ryan, Philip J., Yao, Song T., Stefanidis, Aneta, Oldfield, Brian J.

“…Much progress has been made during the past 30 years with respect to elucidating the neural and endocrine pathways by which bodily needs for water and energy…”
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Specific Dietary Polyphenols Attenuate Atherosclerosis in Apolipoprotein E–Knockout Mice by Alleviating Inflammation and Endothelial Dysfunction by Loke, Wai Mun, Proudfoot, Julie M, Hodgson, Jonathan M, McKinley, Allan J, Hime, Neil, Magat, Maria, Stocker, Roland, Croft, Kevin D

“…OBJECTIVE—Animal and clinical studies have suggested that polyphenols in fruits, red wine, and tea may delay the development of atherosclerosis through their…”
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Heavy metal (PTE) ecotoxicology, data review: Traditional vs. a compositional approach by Mullineaux, S.T., McKinley, J.M., Marks, N.J., Scantlebury, D.M., Doherty, R.

“…Potentially Toxic Elements (PTEs) otherwise known as heavy metals are ubiquitous in soils and can have a range of negative health and environmental impacts. In…”
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Pure dietary flavonoids quercetin and (-)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men by WAI MUN LOKE, HODGSON, Jonathan M, PROUDFOOT, Julie M, MCKINLEY, Allan J, PUDDEY, Ian B, CROFT, Kevin D

“…Dietary flavonoids may improve endothelial function and ultimately lead to beneficial cardiovascular effects. The objective was to assess whether pure dietary…”
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Neural regulation of inflammation: no neural connection from the vagus to splenic sympathetic neurons by Bratton, B. O., Martelli, D., McKinley, M. J., Trevaks, D., Anderson, C. R., McAllen, R. M.

“…The ‘inflammatory reflex’ acts through efferent neural connections from the central nervous system to lymphoid organs, particularly the spleen, that suppress…”
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The cholinergic anti-inflammatory pathway: A critical review by Martelli, D, McKinley, M.J, McAllen, R.M

“…Abstract From a critical review of the evidence on the cholinergic anti-inflammatory pathway and its mode of action, the following conclusions were reached…”
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Reflex control of inflammation by sympathetic nerves, not the vagus by Martelli, D., Yao, S. T., McKinley, M. J., McAllen, R. M.

“…Key points It is believed that the CNS controls inflammation via the autonomic nervous system, but the strength of this action and the neural pathways…”
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Outcomes following excision of Morton's interdigital neuroma: a prospective study by Bucknall, V, Rutherford, D, MacDonald, D, Shalaby, H, McKinley, J, Breusch, S J

“…This is the first prospective study to report the pre- and post-operative patient reported outcomes and satisfaction scores following excision of interdigital…”
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Artificial intelligence-enhanced volumetric laser endomicroscopy improves dysplasia detection in Barrett’s esophagus in a randomized cross-over study by Kahn, Allon, McKinley, Matthew J., Stewart, Molly, Wang, Kenneth K., Iyer, Prasad G., Leggett, Cadman L., Trindade, Arvind J.

“…Volumetric laser endomicroscopy (VLE) is an advanced endoscopic imaging tool that can improve dysplasia detection in Barrett’s esophagus (BE). However, VLE…”
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Suppression of Avian Influenza Transmission in Genetically Modified Chickens by Lyall, Jon, Irvine, Richard M, Sherman, Adrian, McKinley, Trevelyan J, Núñez, Alejandro, Purdie, Auriol, Outtrim, Linzy, Brown, Ian H, Rolleston-Smith, Genevieve, Sang, Helen, Tiley, Laurence

“…Infection of chickens with avian influenza virus poses a global threat to both poultry production and human health that is not adequately controlled by…”
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Integrating Competing Demands of Osmoregulatory and Thermoregulatory Homeostasis by McKinley, Michael J, Martelli, Davide, Pennington, Glenn L, Trevaks, David, McAllen, Robin M

“…Mammals are characterized by a stable core body temperature. When maintenance of core temperature is challenged by ambient or internal heat loads, mammals…”
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Comparison of Bayesian approaches for developing prediction models in rare disease: application to the identification of patients with Maturity-Onset Diabetes of the Young by Cardoso, Pedro, McDonald, Timothy J, Patel, Kashyap A, Pearson, Ewan R, Hattersley, Andrew T, Shields, Beverley M, McKinley, Trevelyan J

“…Clinical prediction models can help identify high-risk patients and facilitate timely interventions. However, developing such models for rare diseases presents…”
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