Search Results - "McKeon, J."

High–Reynolds Number Wall Turbulence by Smits, A J, McKeon, B J, Marusic, I

“…We review wall-bounded turbulent flows, particularly high–Reynolds number, zero–pressure gradient boundary layers, and fully developed pipe and channel flows…”
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Critical-Layer Structures and Mechanisms in Elastoinertial Turbulence by Shekar, Ashwin, McMullen, Ryan M, Wang, Sung-Ning, McKeon, Beverley J, Graham, Michael D

“…Simulations of elastoinertial turbulence (EIT) of a polymer solution at low Reynolds number are shown to display localized polymer stretch fluctuations. These…”
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Sustained delivery of thermostabilized chABC enhances axonal sprouting and functional recovery after spinal cord injury by Lee, Hyunjung, McKeon, Robert J, Bellamkonda, Ravi V

“…Chondroitin sulfate proteoglycans (CSPGs) are a major class of axon growth inhibitors that are up-regulated after spinal cord injury (SCI) and contribute to…”
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Phase relationships between large and small scales in the turbulent boundary layer by Jacobi, I., McKeon, B. J.

“…The apparent amplitude modulation effect between large- and small-scale motions in the turbulent boundary layer, including both streamwise and wall-normal…”
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In situ gelling hydrogels for conformal repair of spinal cord defects, and local delivery of BDNF after spinal cord injury by Jain, Anjana, Kim, Young-Tae, McKeon, Robert J., Bellamkonda, Ravi V.

“…Permanent functional loss usually occurs after injury to the spinal cord. Currently, a clinical strategy to promote regeneration in the injured spinal cord…”
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Lagrangian gradient regression for the detection of coherent structures from sparse trajectory data by Harms, Tanner D., Brunton, Steven L., McKeon, Beverley J.

“…Complex flows are often characterized using the theory of Lagrangian coherent structures (LCS), which leverages the motion of flow-embedded tracers to…”
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Sustained delivery of activated Rho GTPases and BDNF promotes axon growth in CSPG-rich regions following spinal cord injury by Jain, Anjana, McKeon, Robert J, Brady-Kalnay, Susann M, Bellamkonda, Ravi V

“…Spinal cord injury (SCI) often results in permanent functional loss. This physical trauma leads to secondary events, such as the deposition of inhibitory…”
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Serum cartilage oligomeric matrix protein (sCOMP) is elevated in patients with knee osteoarthritis: a systematic review and meta-analysis by Hoch, J.M, Mattacola, C.G, Medina McKeon, J.M, Howard, J.S, Lattermann, C

“…Summary Objective To be used in diagnostic studies, it must be demonstrated that biomarkers can differentiate between diseased and non-diseased patients…”
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Commentary on the New National Institute for Health and Care Excellence Guideline for Metastatic Spinal Cord Compression by Growcott, S., Renninson, E., Rayner, L., McKeon, J., Ayre, G., Comins, C., Challapalli, A., Owadally, W., Beasley, M., Hawley, L., Hilman, S., Strawson-Smith, T., Bahl, A.

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The Chondroitin Sulfate Proteoglycans Neurocan and Phosphacan Are Expressed by Reactive Astrocytes in the Chronic CNS Glial Scar by McKeon, Robert J, Jurynec, Michael J, Buck, Charles R

“…Chondroitin sulfate proteoglycans (CS-PGs) expressed by reactive astrocytes may contribute to the axon growth-inhibitory environment of the injured CNS. The…”
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On the design of optimal compliant walls for turbulence control by Luhar, M., Sharma, A. S., McKeon, B. J.

“…This paper employs the resolvent framework to consider the design of compliant walls for turbulent skin friction reduction. Specifically, the effects of simple…”
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CS-4,6 is differentially upregulated in glial scar and is a potent inhibitor of neurite extension by Gilbert, Ryan J., McKeon, Robert J., Darr, Aniq, Calabro, Anthony, Hascall, Vincent C., Bellamkonda, Ravi V.

“…The precise contribution of different CS-GAGs to CSPG-mediated inhibition of axonal growth after CNS injury is unknown. Quantification of the CS-GAGs in…”
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Unsteady force measurements in sphere flow from subcritical to supercritical Reynolds numbers by Norman, A. K., McKeon, B. J.

“…The flow over a smooth sphere is examined in the Reynolds number range of 5.0 × 10 4  <  Re  < 5.0 × 10 5 via measurements of the fluctuating forces and…”
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A study of the three-dimensional spectral energy distribution in a zero pressure gradient turbulent boundary layer by LeHew, J., Guala, M., McKeon, B. J.

“…Time-resolved particle image velocimetry (PIV) measurements performed in wall parallel planes at three wall normal locations, y +  = 34, 108, and 278, in a…”
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Targeted downregulation of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase significantly mitigates chondroitin sulfate proteoglycan-mediated inhibition by Karumbaiah, Lohitash, Anand, Sanjay, Thazhath, Rupal, Zhong, Yinghui, Mckeon, Robert J., Bellamkonda, Ravi V.

“…Chondroitin sulfate‐4,6 (CS‐E) glycosaminoglycan (GAG) upregulation in astroglial scars is a major contributor to chondroitin sulfate proteoglycan…”
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Spectral location for the universal scaling regime in Martian atmospheric turbulence by Coimbra, Miya C. Y., de la Torre Juárez, Manuel, McKeon, Beverley J., Marín, Mercedes, Murdoch, Naomi, Navarro, Sara, Rodríguez-Manfredi, José Antonio, Stott, Alexander

“…Atmospheric turbulence, irregular fluctuations of the fluid state, is studied on Mars. Universality of the turbulence spectrum underpins atmospheric models…”
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Time-resolved measurements of coherent structures in the turbulent boundary layer by LeHew, J. A., Guala, M., McKeon, B. J.

“…Time-resolved particle image velocimetry was used to examine the structure and evolution of swirling coherent structure (SCS), one interpretation of which is a…”
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One‐Year Landmark Analysis of the Effect of Beta‐Blocker Dose on Survival After Acute Myocardial Infarction by Goldberger, Jeffrey J., Subačius, Haris, Marroquin, Oscar C., Beau, Scott L., Simonson, Jay, Desai, P., Betzen, M., DeLuna, D., Whitehill, J., Hatch, J., Janak, L., Cherry, R., Gonzalez, E., Cruz, I., Johnson, E., Allbritton, C., Derrick, V., Fishman, R., Assalone, V., Mahon, L., Lustgarten, D., Rowen, M., Bessette, M., Alemy, B., Dan, D., Picardi, K., Schuger, C., Dzidowski, J., McCarthy, M., Fields, P., Alexander, S., Nair, G., Kovacs, R., Beasley, D., Strickland, T., Marks, J., Beau, S., Tableriou, J., Griffin, B., Shani, J., Stokes‐McCarthy, M., Tan‐Augenstein, G., Pace, G., Brosnan, H., Hayes, J., Mancl, K., Maassen, K., Fintel, D., Karpf, L., Abraham, T., Campione, K., Martin, E., Bello, D., Viera Fleetwood, I., Tinetti, M., Rock, R., Simonson, J., Barnes, S., Letexier, J., Strothman, M., Mattson, J., Albert Shoultz, C., Ali, S., Abbott, D., Medeiros, M., McKeon, J., Nichols, A., Edwards, T., Watts, C., Alley, C., Romanelli, M., Steffen, D., Henschel, R., Teller, S., Froehlich, L., Bess, R., Warnica, W., Smith, B., Eichman, D., Scarcelli, D., Badhwar, N., Malone, P., Green, D., Iyer, S., Germany, R., Murray, C., Straughn, G., Drennan, K., Marroquin, O., Dennis, L., Farrow, C., Baxendell, L., Grate, S., Enlow, M., Zareba, W., Chaudhary, I., Laduke, P., Conary‐Rocco, V., Caufield, L., Patterson, C.

“…Background Although beta‐blockers are recommended following myocardial infarction (MI), the benefits of long‐term treatment have not been established. The…”
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The effect of a small isolated roughness element on the forces on a sphere in uniform flow by Norman, A. K., McKeon, B. J.

“…The effect of an isolated roughness element on the forces on a sphere was examined for a Reynolds number range of 5 × 10 4  <  Re  < 5 × 10 5 using a novel…”
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Activation of Protease-Activated Receptor-1 Triggers Astrogliosis after Brain Injury by Nicole, Olivier, Goldshmidt, Anna, Hamill, Cecily E, Sorensen, Scott D, Sastre, Aristide, Lyuboslavsky, Polina, Hepler, John R, McKeon, Robert J, Traynelis, Stephen F

“…We have studied the involvement of the thrombin receptor [protease-activated receptor-1 (PAR-1)] in astrogliosis, because extravasation of PAR-1 activators,…”
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