Search Results - "McKenzie, Zachary M."

Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes by Mashtalir, Nazar, D’Avino, Andrew R., Michel, Brittany C., Luo, Jie, Pan, Joshua, Otto, Jordan E., Zullow, Hayley J., McKenzie, Zachary M., Kubiak, Rachel L., St. Pierre, Roodolph, Valencia, Alfredo M., Poynter, Steven J., Cassel, Seth H., Ranish, Jeffrey A., Kadoch, Cigall

“…Mammalian SWI/SNF (mSWI/SNF) ATP-dependent chromatin remodeling complexes are multi-subunit molecular machines that play vital roles in regulating genomic…”
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A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation by Michel, Brittany C., D’Avino, Andrew R., Cassel, Seth H., Mashtalir, Nazar, McKenzie, Zachary M., McBride, Matthew J., Valencia, Alfredo M., Zhou, Qianhe, Bocker, Michael, Soares, Luis M. M., Pan, Joshua, Remillard, David I., Lareau, Caleb A., Zullow, Hayley J., Fortoul, Nora, Gray, Nathanael S., Bradner, James E., Chan, Ho Man, Kadoch, Cigall

“…Mammalian SWI/SNF chromatin remodelling complexes exist in three distinct, final-form assemblies: canonical BAF (cBAF), PBAF and a newly characterized…”
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The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity–independent genomic targeting by Pan, Joshua, McKenzie, Zachary M., D’Avino, Andrew R., Mashtalir, Nazar, Lareau, Caleb A., St. Pierre, Roodolph, Wang, Lu, Shilatifard, Ali, Kadoch, Cigall

“…Perturbations to mammalian switch/sucrose non-fermentable (mSWI/SNF) chromatin remodeling complexes have been widely implicated as driving events in cancer 1 …”
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SMARCB1 is required for widespread BAF complex–mediated activation of enhancers and bivalent promoters by Nakayama, Robert T, Pulice, John L, Valencia, Alfredo M, McBride, Matthew J, McKenzie, Zachary M, Gillespie, Mark A, Ku, Wai Lim, Teng, Mingxiang, Cui, Kairong, Williams, Robert T, Cassel, Seth H, Qing, He, Widmer, Christian J, Demetri, George D, Irizarry, Rafael A, Zhao, Keji, Ranish, Jeffrey A, Kadoch, Cigall

“…Loss of BAF47 destabilizes the BAF complex on chromatin, and reintroduction of BAF47 leads to enhancer activation and Polycomb opposition at bivalent…”
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Barriers to gene exchange in hybridizing field crickets: the role of male courtship effort and cuticular hydrocarbons by Maroja, Luana S, McKenzie, Zachary M, Hart, Elizabeth, Jing, Joy, Larson, Erica L, Richardson, David P

“…Pre-zygotic barriers often involve some form of sexual selection, usually interpreted as female choice, as females are typically the choosier sex. However,…”
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