Search Results - "McKenney, Mary"
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1
CLAMP and Zelda function together to promote Drosophila zygotic genome activation
Published in eLife (03-08-2021)“…During the essential and conserved process of zygotic genome activation (ZGA), chromatin accessibility must increase to promote transcription. Drosophila is a…”
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2
A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma
Published in Blood (15-11-2006)“…This multicenter, open-label, randomized phase 2 study evaluated 2 dose regimens of lenalidomide for relapsed, refractory myeloma. Seventy patients were…”
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3
Multicenter, Phase I, Dose-Escalation Trial of Lenalidomide Plus Bortezomib for Relapsed and Relapsed/Refractory Multiple Myeloma
Published in Journal of clinical oncology (01-12-2009)“…Lenalidomide and bortezomib are active in relapsed and relapsed/refractory multiple myeloma (MM). In preclinical studies, lenalidomide sensitized MM cells to…”
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4
Tailoring treatment for multiple myeloma patients with relapsed and refractory disease
Published in Oncology (Williston Park, N.Y.) (01-03-2010)“…Responses to treatment of relapsed and refractory multiple myeloma are characteristically short, and median survival is as brief as 6 months. Although…”
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5
A phase 2 trial of lenalidomide, bortezomib, and dexamethasone in patients with relapsed and relapsed/refractory myeloma
Published in Blood (06-03-2014)“…In this prospective, multicenter, phase 2 study, 64 patients with relapsed or relapsed and refractory multiple myeloma (MM) received up to 8 21-day cycles of…”
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6
Clinical Outcomes of Non-Traditional Lenalidomide, Bortezomib, and Dexamethasone Regimens in Multiple Myeloma
Published in Blood (05-11-2020)“…Introduction Lenalidomide, bortezomib, and dexamethasone (RVD) is a standard first-line regimen for patients with newly diagnosed multiple myeloma and is…”
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A Phase I/II Study of Twice Weekly Ixazomib Plus Pomalidomide and Dexamethasone in Relapsed and Refractory Multiple Myeloma
Published in Blood (23-11-2021)“…Introduction: Ixazomib is an oral proteasome inhibitor (PI) that is currently approved to be administered once weekly in combination with lenalidomide (LEN)…”
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A Phase I/II Study of Twice Weekly Ixazomib Plus Pomalidomide and Dexamethasone in Relapsed and Refractory Multiple Myeloma: Results from Phase I Dose Escalation Cohorts
Published in Blood (05-11-2020)“…Introduction: Treatment of relapsed and refractory multiple myeloma (RRMM) continues to evolve as most patients are lenalidomide (LEN) refractory at the time…”
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9
Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma
Published in Blood (01-11-2002)“…Thalidomide (Thal) can overcome drug resistance in multiple myeloma (MM) but is associated with somnolence, constipation, and neuropathy. In previous in vitro…”
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10
Sensitivity of evapotranspiration in a wheat field, a forest, and a grassland to changes in climate and direct effects of carbon dioxide
Published in Climatic change (01-04-1989)“…Penman-Monteith models of evapotranspiration for a wheat field in Nebraska, a forest in Tennessee, and a grassland in Kansas were developed based on…”
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11
Paper 1. the mink methodology: background and baseline
Published in Climatic change (01-06-1993)“…A four step methodology, termed MINK, has been developed for study of the regional impacts of climate change and the possible responses thereto. Impacts of the…”
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12
The potential benefits of participating in early‐phase clinical trials in multiple myeloma: long‐term remission in a patient with relapsed multiple myeloma treated with 90 cycles of lenalidomide and bortezomib
Published in European journal of haematology (01-05-2012)“…We present the case of a woman with relapsed multiple myeloma (MM) who received combination lenalidomide and bortezomib therapy for 90 cycles followed by…”
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Phase II Trial of Lenalidomide, Bortezomib, and Dexamethasone In Patients (pts) with Relapsed and Relapsed/Refractory Multiple Myeloma (MM): Updated Efficacy and Safety Data After >2 Years of Follow-up
Published in Blood (19-11-2010)“…Abstract 3049 Single-agent bortezomib (btz) and lenalidomide (len)-dexamethasone (dex) are associated with higher rates of response and improved survival vs…”
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Lenalidomide, Bortezomib, and Dexamethasone in Patients with Relapsed or Relapsed/Refractory Multiple Myeloma (MM): Encouraging Response Rates and Tolerability with Correlation of Outcome and Adverse Cytogenetics in a Phase II Study
Published in Blood (16-11-2008)“…Background: Bortezomib (VELCADE®, Bz) is approved for the treatment of multiple myeloma (MM). Lenalidomide (Revlimid®, Len) plus dexamethasone (Dex) is…”
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Lenalidomide, Bortezomib, and Dexamethasone (Rev/Vel/Dex) in Patients with Relapsed or Relapsed/Refractory Multiple Myeloma (MM): Preliminary Results of a Phase II Study
Published in Blood (16-11-2007)“…Background: Single-agent bortezomib (VELCADE®, Vel) and lenalidomide (Revlimid®, Rev) plus dexamethasone (Dex) are approved for relapsed MM patients (pts)…”
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16
Triplet sensitization and exciplex quenching of the photochemical reaction between phenanthrene and dimethyl fumarate
Published in Journal of the American Chemical Society (01-08-1978)Get full text
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Paper 2. agricultural impacts of and responses to climate change in the Missouri-Iowa-Nebraska-Kansas (MINK) region
Published in Climatic change (01-06-1993)“…The climate of the 1930s was used as an analog of the climate that might occur in Missouri, Iowa, Nebraska and Kansas (the MINK region) as a consequence of…”
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Investigating the Basis of tRNA Editing and Modification Enzyme Coactivation in Trypanosoma brucei
Published 01-01-2018“…In all domains of life, transfer RNAs (tRNAs) undergo many post-transcriptional modifications and editing events that fine-tune their structural and functional…”
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Dissertation -
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A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma. Commentary
Published in Blood (2006)Get full text
Journal Article -
20
Agricultural impacts of and responses to climate change in the Missouri-Iowa-Nebraska-Kansas (Mink) region
Published in Climatic change (01-06-1993)“…As part of the MINK (Missouri-Iowa-Nebraska-Kansas) study, crop production was simulated for a set of representative farms across the MINK region under the…”
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