Search Results - "McKenna, S L"

Expression of MxA in esophageal cancer cell lines can influence sensitivity to chemotherapeutic agents but this does not require apoptosis by Hayes, R. M., O'Donovan, T. R., McKenna, S. L.

“…Esophageal cancer is a poor prognosis cancer characterized by intrinsic or acquired resistance to chemotherapeutic agents. The primary determinants of…”
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Curcumin induces apoptosis-independent death in oesophageal cancer cells by O'Sullivan-Coyne, G, O'Sullivan, G C, O'Donovan, T R, Piwocka, K, McKenna, S L

“…Background: Oesophageal cancer incidence is increasing and survival rates remain extremely poor. Natural agents with potential for chemoprevention include the…”
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Pulmonary outcomes following specialized respiratory management for acute cervical spinal cord injury: a retrospective analysis by Zakrasek, E C, Nielson, J L, Kosarchuk, J J, Crew, J D, Ferguson, A R, McKenna, S L

“…Study design: Retrospective analysis. Objectives: To identify multivariate interactions of respiratory function that are sensitive to spinal cord injury level…”
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Management factors associated with time-to-onset and fecal egg/oocyst counts of gastrointestinal parasites in heifer calves on Kenyan smallholder farms by Kimeli, P, VanLeeuwen, J, Gitau, GK, Heider, LC, McKenna, SL, Greenwood, SJ

“…•Helminths with strongyle-type eggs and coccidia were the most common endoparasites.•Coccidia had shorter time-to-onset (TTO) of infection as compared to…”
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Effects of Calliandra and Sesbania on Daily Milk Production in Dairy Cows on Commercial Smallholder Farms in Kenya by Wichtel, J. J., Walton, C., McKenna, S. L., Gitau, G. K., VanLeeuwen, John, Makau, D. N., Muraya, J.

“…There is a growing interest in protein supplementation of dairy-cow diets using leguminous shrubs. The study objective was to ascertain the association between…”
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Evaluation of Cellular Uptake and Gene Transfer Efficiency of Pegylated Poly-l-lysine Compacted DNA:  Implications for Cancer Gene Therapy by Walsh, M, Tangney, M, O'Neill, M. J, Larkin, J. O, Soden, D. M, McKenna, S. L, Darcy, R, O'Sullivan, G. C, O'Driscoll, C. M

“…Recent success in phase I/II clinical trials (Konstan, M. W.; Davis, P. B.; Wagener, J. S.; Hilliard, K. A.; Stern, R. C.; Milgram, L. J.; Kowalczyk, T. H.;…”
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Laboratory evaluation of 3M Petrifilms and University of Minnesota Bi-plates as potential on-farm tests for clinical mastitis by McCarron, J L, Keefe, G P, McKenna, S L B, Dohoo, I R, Poole, D E

“…The objective was to determine test characteristics and compare 2 potential on-farm culture systems for clinical mastitis, the Minnesota Easy Culture System II…”
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The BH3 mimetic HA14-1 enhances 5-fluorouracil-induced autophagy and type II cell death in oesophageal cancer cells by Nyhan, M J, O'Donovan, T R, Elzinga, B, Crowley, L C, O'Sullivan, G C, McKenna, S L

“…Background: Resistance to chemotherapeutic agents has been associated with a failure of cancer cells to induce apoptosis. Strategies to restore apoptosis have…”
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Evaluation of the University of Minnesota Tri-plate and 3M Petrifilm for the isolation of Staphylococcus aureus and Streptococcus species from clinically mastitic milk samples by McCarron, J L, Keefe, G P, McKenna, S L, Dohoo, I R, Poole, D E

“…The primary objective was to compare microbiological results of the University of Minnesota Tri-plate and the 3M Petrifilm Staph Express (STX) Count Plate to…”
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Elevated Bcr-Abl expression levels are sufficient for a haematopoietic cell line to acquire a drug-resistant phenotype by KEESHAN, K, MILLS, K. I, COTTER, T. G, MCKENNA, S. L

“…A characteristic feature of chronic myeloid leukaemia (CML) is the inevitable advancement from a treatable chronic phase to a fatal, drug-resistant stage…”
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Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals by O'GORMAN, D. M, MCKENNA, S. L, MCGAHON, A. J, KNOX, K. A, COTTER, T. G

“…Drug resistance remains a serious limiting factor in the treatment of acute myeloid leukaemia (AML) either at initial presentation or following primary or…”
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Evaluation of selective dry cow treatment following on-farm culture: risk of postcalving intramammary infection and clinical mastitis in the subsequent lactation by Cameron, M, McKenna, S L, MacDonald, K A, Dohoo, I R, Roy, J P, Keefe, G P

“…The objective of the study was to evaluate the utility of a Petrifilm-based on-farm culture system when used to make selective antimicrobial treatment…”
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Relationships between type of hoof lesion and behavioral signs of lameness in Holstein cows housed in Canadian tiestall facilities by Jewell, M T, Cameron, M, McKenna, S L, Cockram, M S, Sanchez, J, Keefe, G P

“…Although foot pain can affect gait, the presence of a hoof lesion may or may not cause the cow to show visible changes in their gait. This can be dependent on…”
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β‐Catenin transcriptional activity is inhibited downstream of nuclear localisation and is not influenced by IGF signalling in oesophageal cancer cells by Kiely, B., O'Donovan, R.T., McKenna, S.L., O'Sullivan, G.C.

“…Aberrant expression/localisation of β‐catenin has been implicated in the progression of oesophageal cancer. As a member of the Wnt‐signalling pathway,…”
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Evaluation of selective dry cow treatment following on-farm culture: Milk yield and somatic cell count in the subsequent lactation by Cameron, M, Keefe, G P, Roy, J-P, Stryhn, H, Dohoo, I R, McKenna, S L

“…Compared with blanket dry cow therapy (DCT), the selective antimicrobial treatment of cows based upon on-farm culture results has the potential to reduce the…”
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Randomized control trial to investigate compliance with, and impacts of, cow comfort recommendations on smallholder dairy farms in Kenya by Kariuki, E.N., VanLeeuwen, J.A., McKenna, S.L., Heider, L.C., Gitau, G.K., Muasya, D.W.

“…Smallholder dairy farmers (SDF) in developing countries often have limited understanding on the importance of cow comfort. We conducted a randomized controlled…”
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Comparison of fecal pooling strategies for detection of Mycobacterium avium ssp. paratuberculosis in cattle by McKenna, S L B, Ritter, C, Dohoo, I, Keefe, G P, Barkema, H W

“…In herds with typical moderate to low within-herd prevalence, testing for Mycobacterium avium ssp. paratuberculosis (MAP), the infectious agent of Johne's…”
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High Bcr-Abl expression prevents the translocation of Bax and Bad to the mitochondrion by KEESHAN, K, COTTER, T. G, MCKENNA, S. L

“…Bcr-Abl is a constitutively active tyrosine kinase involved in the development and progression of chronic myeloid leukaemia (CML). It has been demonstrated…”
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Agreement between three ELISAs for Mycobacterium avium subsp. paratuberculosis in dairy cattle by McKenna, S.L.B., Barkema, H.W., Keefe, G.P., Sockett, D.C.

“…During a 10-month period in 1999, 994 serum and tissue samples were collected from dairy cows at slaughter in eastern Canada. The sources of these cattle were…”
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Evaluation of environmental and comfort improvements on affective welfare in heifer calves on smallholder dairy farms by Kimeli, P., VanLeeuwen, J., Gitau, G.K., Heider, L.C., McKenna, S.L., Greenwood, S.J., Richards, S.

“…A controlled trial on zero-grazed smallholder dairy farms was conducted to determine the effect of environmental and comfort improvements on sucking and lying…”
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