Search Results - "McKenna, Margaret A"
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Fas Binding to Calmodulin Regulates Apoptosis in Osteoclasts
Published in The Journal of biological chemistry (19-08-2005)“…Promotion of osteoclast apoptosis is one therapeutic approach to osteoporosis. Calmodulin, the major intracellular Ca 2+ receptor, modulates both…”
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2
RANKL Regulates Fas Expression and Fas-Mediated Apoptosis in Osteoclasts
Published in Journal of bone and mineral research (01-01-2005)Get full text
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Osteoclast Apoptosis: The Role of Fas in Vivo and in Vitro
Published in Endocrinology (Philadelphia) (01-12-2003)“…Both the number and the activity of osteoclasts are critical for maintaining normal bone turnover. The number is determined by rates of cell differentiation…”
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4
RANKL Regulates Fas Expression and Fas‐Mediated Apoptosis in Osteoclasts
Published in Journal of bone and mineral research (01-01-2005)“…Osteoclast apoptosis is an influential determinant of osteoclast bone‐resorbing activity. RANKL, a critical factor for osteoclastogenesis, is also important in…”
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5
AZT enhances osteoclastogenesis and bone loss
Published in AIDS research and human retroviruses (01-06-2004)“…A variety of metabolic complications have been reported to be associated with highly active antiretroviral therapy (HAART), including osteopenia and…”
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6
Effects of Cyclosporine on Osteoclast Activity: Inhibition of Calcineurin Activity With Minimal Effects on Bone Resorption and Acid Transport Activity
Published in Journal of bone and mineral research (01-03-2003)“…Cyclosporine results in rapid and profound bone loss in transplant patients, an effect ascribed to osteoclasts. Cyclosporine, complexed with the appropriate…”
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7
Osteoclasts Secrete the Chemotactic Cytokine Mim-1
Published in Biochemical and biophysical research communications (16-02-2001)“…Osteoclasts are terminally differentiated, multinucleated cells of monocytic origin. In this study, we report that osteoclasts secrete a 35 kD protein and that…”
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8
Calmodulin and HIV type 1: interactions with Gag and Gag products
Published in AIDS research and human retroviruses (10-10-2000)“…The level of calmodulin increases in cells expressing HIV-1 envelope glycoprotein. Although a calmodulin increase is bound to alter many cellular metabolic and…”
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Regulation of Avian Osteoclastic H+-ATPase and Bone Resorption by Tamoxifen and Calmodulin Antagonists
Published in The Journal of biological chemistry (24-05-1996)“…We used highly purified avian osteoclasts and isolated membranes from osteoclasts to study effects of tamoxifen, 4-hydroxytamoxifen, calmodulin antagonists,…”
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10
TQM and Services: Implementing Change in the NHS
Published in International journal of contemporary hospitality management (01-02-1992)“…Examines the developing importance of the quality issue in the service sector and highlights common barriers to the successful implementation of total quality…”
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11
Northern Ireland Tourism: A Quality Perspective
Published in Managing service quality (01-04-1994)“…Discusses the service quality matrix as one strategy in attaining and maintaining service excellence in relation to Northern Ireland's hospitality record…”
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12
Regulation of Osteoclastic Bone Resorption by Glucose
Published in Biochemical and biophysical research communications (27-06-1997)“…Osteoclasts degrade bone by pumping molar quantities of HCl to dissolve the calcium salts of bone, an energy intensive process evidently supported by abundant…”
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13
Research Report: Hospitality Graduate and Diplomate Labour Market Experiences
Published in Journal of European industrial training (01-03-1992)“…The labour market experience of graduates and diplomates is a subject currently being explored in the United Kingdom. Reports on the findings of a study…”
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14
Osteoclastogenesis: the role of calcium and calmodulin
Published in Critical reviews in eukaryotic gene expression (2005)“…Enhanced osteoclastogenesis is an important pathological feature in several aging-associated bone diseases. Thus, research activities on osteoclastogenesis…”
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15
Regulation of avian osteoclastic H+ -ATPase and bone resorption by tamoxifen and calmodulin antagonists. Effects independent of steroid receptors
Published in The Journal of biological chemistry (24-05-1996)“…We used highly purified avian osteoclasts and isolated membranes from osteoclasts to study effects of tamoxifen, 4-hydroxytamoxifen, calmodulin antagonists,…”
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16
Differential effects of tamoxifen-like compounds on osteoclastic bone degradation, H+-ATPase activity, calmodulin-dependent cyclic nucleotide phosphodiesterase activity, and calmodulin binding
Published in Journal of cellular biochemistry (01-09-1997)“…We studied effects of calmodulin antagonists on osteoclastic activity and calmodulin‐dependent HCl transport. The results were compared to effects on the…”
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17
Tamoxifen inhibits phorbol ester stimulated osteoclastic bone resorption: an effect mediated by calmodulin
Published in Biochemistry and cell biology (2000)“…Tamoxifen inhibits bone resorption by disrupting calmodulin-dependent processes. Since tamoxifen inhibits protein kinase C in other cells, we compared the…”
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18
Contract catering: a positional paper
Published in International journal of hospitality management (01-06-2001)“…The contract catering sector of the UK hospitality industry has expanded rapidly in scale and scope, yet few contemporary hospitality researchers acknowledge…”
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19
Research Report Hospitality Graduate and Diplomate LabourMarket Experiences
Published in Journal of European industrial training (01-03-1992)“…The labour market experience of graduates and diplomates is a subject currently being explored in the United Kingdom. Reports on the findings of a study…”
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