Search Results - "McKenna, Kathy L"

Airway Epithelial Cells Regulate the Functional Phenotype of Locally Differentiating Dendritic Cells: Implications for the Pathogenesis of Infectious and Allergic Airway Disease by Rate, Angela, Upham, John W, Bosco, Anthony, McKenna, Kathy L, Holt, Patrick G

“…Atopic asthma pathogenesis is driven by the combined effects of airway inflammation generated during responses to viral infections and aeroallergens, and both…”
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Airway epithelial cells condition dendritic cells to express multiple immune surveillance genes by Rate, Angela, Bosco, Anthony, McKenna, Kathy L, Holt, Patrick G, Upham, John W

“…Increasing evidence suggests that crosstalk between airway epithelial cells (AEC) and adjacent dendritic cells (DC) tightly regulates airway mucosal DC…”
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A Network Modeling Approach to Analysis of the Th2 Memory Responses Underlying Human Atopic Disease by Bosco, Anthony, McKenna, Kathy L, Firth, Martin J, Sly, Peter D, Holt, Patrick G

“…Complex cellular functions within immunoinflammatory cascades are conducted by networks of interacting genes. In this study, we employed a network modeling…”
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Identification of Novel Th2-Associated Genes in T Memory Responses to Allergens by Bosco, Anthony, McKenna, Kathy L, Devitt, Catherine J, Firth, Martin J, Sly, Peter D, Holt, Patrick G

“…Atopic diseases are associated with hyperexpression of Th2 cytokines by allergen-specific T memory cells. However, clinical trials with recently developed Th2…”
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