Search Results - "McKeithan, T W"

The miRNA-17∼92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation by Rao, E, Jiang, C, Ji, M, Huang, X, Iqbal, J, Lenz, G, Wright, G, Staudt, L M, Zhao, Y, McKeithan, T W, Chan, W C, Fu, K

“…The median survival of patients with mantle cell lymphoma (MCL) ranges from 3 to 5 years with current chemotherapeutic regimens. A common secondary genomic…”
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BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription by BROCKE-HEIDRICH, K, GE, B, CVIJIC, H, PFEIFER, G, LÖFFLER, D, HENZE, C, MCKEITHAN, T. W, HORN, F

“…BCL3 is a proto-oncogene affected by chromosomal translocations in some patients with chronic lymphocytic leukemia. It is an IkappaB family protein that is…”
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Kinetic Proofreading in T-Cell Receptor Signal Transduction by Mckeithan, Timothy W.

“…Like other cell-surface receptors with intrinsic or associated protein-tyrosine kinase activity, the T-cell receptor complex undergoes a number of…”
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The miRNA-17 similar to 92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation by Rao, E, Jiang, C, Ji, M, Huang, X, Iqbal, J, Lenz, G, Wright, G, Staudt, L M, Zhao, Y, McKeithan, T W, Chan, W C, Fu, K

“…The median survival of patients with mantle cell lymphoma (MCL) ranges from 3 to 5 years with current chemotherapeutic regimens. A common secondary genomic…”
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Combined copy number and mutation analysis identifies oncogenic pathways associated with transformation of follicular lymphoma by Bouska, A, Zhang, W, Gong, Q, Iqbal, J, Scuto, A, Vose, J, Ludvigsen, M, Fu, K, Weisenburger, D D, Greiner, T C, Gascoyne, R D, Rosenwald, A, Ott, G, Campo, E, Rimsza, L M, Delabie, J, Jaffe, E S, Braziel, R M, Connors, J M, Wu, C-I, Staudt, L M, D‘Amore, F, McKeithan, T W, Chan, W C

“…Follicular lymphoma (FL) is typically an indolent disease, but 30–40% of FL cases transform into an aggressive lymphoma (tFL) with a poor prognosis. To…”
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Replication of a Common Fragile Site, FRA3B, Occurs Late in S Phase and is Delayed Further Upon Induction: Implications for the Mechanism of Fragile Site Induction by Le Beau, Michelle M., Rassool, Feyruz V., Neilly, Mary E., Espinosa, Rafael, Glover, Thomas W., Smith, David I., McKeithan, Timothy W.

“…The FRA3B at 3p14.2 is the most highly expressed of the common fragile sites observed when DNA replication is perturbed by aphidicolin or folate stress. The…”
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The Ankyrin Repeat Domains of the NF-κB Precursor p105 and the Protooncogene bcl-3 Act as Specific Inhibitors of NF-κB DNA Binding by Hatada, Eunice N., Nieters, Alexandra, Wulczyn, F. Gregory, Naumann, Michael, Meyer, Ralf, Nucifora, Giuseppina, McKeithan, Timothy W., Scheidereit, Claus

“…The inducible pleiotropic transcription factor NF-κ B is composed of two subunits, p50 and p65. The p50 subunit is encoded on the N-terminal half of a 105-kDa…”
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BCL3 encodes a nuclear protein which can alter the subcellular location of NF-kappa B proteins by QIANG ZHANG, DIDONATO, J. A, KARIN, M, MCKEITHAN, T. W

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification of the Gene Associated with the Recurring Chromosomal Translocations t(3;14)(q27;q32) and t(3;22)(q27;q11) in B-Cell Lymphomas by Baron, Beverly W., Nucifora, Giuseppina, McCabe, Norah, Espinosa, Rafael, Le Beau, Michael M.

“…Chromosomal translocations involving chromosome 3, band q27, are among the most common rearrangements in B-cell non-Hodgkin lymphoma. From a bacteriophage λ…”
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Complete lymphoid chimerism and chronic graft-versus-host disease in an infant recipient of a hepatic allograft from an HLA-homozygous parental living donor by WHITINGTON, P. F, RUBIN, C. M, ALONSON, E. M, MCKEITHAN, T. W, ANASTASI, J, HART, J, THISTLEYTHWAITE, J. R

“…Living-related donor liver transplantation (LDLT) is an accepted approach to pediatric liver transplantation. Parental donation imposes a significant risk of…”
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Resolution of Helicobacter pylori-associated gastric lymphoproliferative disease in a child by Blecker, U, McKeithan, T W, Hart, J, Kirschner, B S

“…A possible causative association between Helicobacter pylori infection and gastric lymphoproliferative disorders has recently been recognized. The case of a…”
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Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice by TIONG ONG, S, HACKBARTH, M. L, DEGENSTEIN, L. C, BAUNOCH, D. A, ANASTASI, J, MCKEITHAN, T. W

“…The candidate proto-oncogene BCL3 was isolated through its involvement in the t(14;19) found in chronic lymphocytic leukemia and other B-cell neoplasms. As a…”
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Preferential Integration of Marker DNA into the Chromosomal Fragile Site at 3p14: An Approach to Cloning Fragile Sites by Rassool, Feyruz V., McKeithan, Timothy W., Neilly, Mary E., Van Melle, Elizabeth, Espinosa, Rafael, Le Beau, Michelle M.

“…Fragile sites are specific regions of chromosomes that are prone to breakage. In cells cultured under conditions that induce fragile site expression, high…”
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The proto-oncogene BCL-3 encodes an IκB protein by KERR, L. D, DUCKETT, C. S, WAMSLEY, P, QIANG ZHANG, CHIAO, P, NABEL, G, MCKEITHAN, T. W, BAEUERLE, P. A, VERMA, I. M

“…The bcl-3 gene product, overexpressed in chronic lymphocytic leukemia (CLL) patients with the translocation t(14;19), is a member of the I kappa B family. The…”
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Involvement of the AML1 Gene in the t(3;21) in Therapy-Related Leukemia and in Chronic Myeloid Leukemia in Blast Crisis by Nucifora, Giuseppina, Birn, Debra J., Espinosa III, Rafael, Erickson, Paul, LeBeau, Michelle M., Roulston, Diane, McKeithan, Timothy W., Drabkin, Harry, Rowley, Janet D.

“…A nonrandom translocation between chromosomes 3 and 21, t(3;21)(q26.2;q22) has been detected in patients with a myelodysplastic syndrome or acute myeloid…”
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Cloning of the Chromosome Translocation Breakpoint Junction of the t(14;19) in Chronic Lymphocytic Leukemia by McKeithan, Timothy W., Rowley, Janet D., Shows, Thomas B., Diaz, Manuel O.

“…Our laboratory has reported that t(14;19)(q32;q13.1) is a recurring translocation in the neoplastic cells of patients with chronic lymphocytic leukemia. In the…”
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Morphology in Ki-1(CD30)-positive non-Hodgkin's lymphoma is correlated with clinical features and the presence of a unique chromosomal abnormality, t(2;5)(p23;q35) by Bitter, M A, Franklin, W A, Larson, R A, McKeithan, T W, Rubin, C M, Le Beau, M M, Stephens, J K, Vardiman, J W

“…Ten patients with strongly Ki-1(CD30)-positive non-Hodgkin's lymphoma (NHL) were identified at our institution during the past 5 years. Based on morphology,…”
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Gene Encoding the α Chain of the T-Cell Receptor is Moved Immediately Downstream of c-myc in a Chromosomal 8;14 Translocation in a Cell Line from a Human T-Cell Leukemia by Shima, Elizabeth A., Le Beau, Michelle M., McKeithan, Timothy W., Minowada, Jun, Showe, Louise C., Mak, Tak W., Minden, Mark D., Rowley, Janet D., Diaz, Manuel O.

“…The SKW-3 cell line, which was established from the malignant cells of a patient with T-cell chronic lymphocytic leukemia, is characterized by a translocation…”
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The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control by Ohno, H, Takimoto, G, McKeithan, T W

“…A gene, bcl-3, is found on chromosome 19 adjacent to the breakpoints in the translocation t(14;19)(q32;q13.1), which occurs in some cases of chronic…”
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Direct Cloning of DNA Sequences from the Common Fragile Site Region at Chromosome Band 3p14.2 by Rassool, Feyruz V., Le Beau, Michelle M., Shen, Mei-Ling, Neilly, Mary E., Espinosa III, Rafael, Ong, S.Tiong, Boldog, Ferenc, Drabkin, Harry, McCarroll, Robert, McKeithan, Timothy W.

“…Despite several lines of evidence suggesting that common chromosomal fragile sites are biologically important as hot spots for recombination, their structure…”
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