Search Results - "McKeith, Ian G."

Inflammation in dementia with Lewy bodies by Amin, Jay, Erskine, Daniel, Donaghy, Paul C., Surendranathan, Ajenthan, Swann, Peter, Kunicki, Amy P., Boche, Delphine, Holmes, Clive, McKeith, Ian G., O'Brien, John T., Teeling, Jessica L., Thomas, Alan J.

“…Dementia with Lewy bodies (DLB) is the second most common neurodegenerative cause of dementia, behind Alzheimer's disease (AD). The profile of inflammation in…”
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Education, the brain and dementia: neuroprotection or compensation? by Brayne, Carol, Ince, Paul G., Keage, Hannah A. D., McKeith, Ian G., Matthews, Fiona E., Polvikoski, Tuomo, Sulkava, Raimo

“…The potential protective role of education for dementia is an area of major interest. Almost all older people have some pathology in their brain at death but…”
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Clinical prevalence of Lewy body dementia by Kane, Joseph P M, Surendranathan, Ajenthan, Bentley, Allison, Barker, Sally A H, Taylor, John-Paul, Thomas, Alan J, Allan, Louise M, McNally, Richard J, James, Peter W, McKeith, Ian G, Burn, David J, O'Brien, John T

“…The prevalence of dementia with Lewy bodies (DLB) and dementia in Parkinson's disease (PDD) in routine clinical practice is unclear. Prevalence rates observed…”
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Diagnostic procedures for Parkinson's disease dementia: Recommendations from the movement disorder society task force by Dubois, Bruno, Burn, David, Goetz, Christopher, Aarsland, Dag, Brown, Richard G., Broe, Gerald A., Dickson, Dennis, Duyckaerts, Charles, Cummings, Jefferey, Gauthier, Serge, Korczyn, Amos, Lees, Andrew, Levy, Richard, Litvan, Irene, Mizuno, Yoshikuni, McKeith, Ian G., Olanow, C. Warren, Poewe, Werner, Sampaio, Cristina, Tolosa, Eduardo, Emre, Murat

“…A preceding article described the clinical features of Parkinson's disease dementia (PD‐D) and proposed clinical diagnostic criteria for “probable” and…”
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Extravascular fibrinogen in the white matter of Alzheimer’s disease and normal aged brains: implications for fibrinogen as a biomarker for Alzheimer’s disease by McAleese, Kirsty E., Graham, Sophie, Dey, Madhurima, Walker, Lauren, Erskine, Daniel, Johnson, Mary, Johnston, Eleanor, Thomas, Alan J., McKeith, Ian G., DeCarli, Charles, Attems, Johannes

“…The blood–brain barrier (BBB) regulates cerebrovascular permeability and leakage of blood‐derived fibrinogen. Dysfunction of the BBB has been associated with…”
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Two-Year Progression from Mild Cognitive Impairment to Dementia: To What Extent Do Different Definitions Agree? by Matthews, Fiona E., Stephan, Blossom C. M., McKeith, Ian G., Bond, John, Brayne, Carol

“…OBJECTIVES: To determine the 2‐year outcome from 16 different current classifications of mild cognitive impairment (MCI) in a population‐based sample. DESIGN:…”
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Clinical symptoms in mild cognitive impairment with Lewy bodies: Frequency, time of onset, and discriminant ability by Donaghy, Paul C., Hamilton, Calum, Durcan, Rory, Lawley, Sarah, Barker, Sally, Ciafone, Joanna, Barnett, Nicola, Olsen, Kirsty, Firbank, Michael, Roberts, Gemma, Lloyd, Jim, Allan, Louise M., Saha, Ranjan, McKeith, Ian G., O'Brien, John T., Taylor, John‐Paul, Thomas, Alan J.

“…Background and purpose Mild cognitive impairment with Lewy bodies (MCI‐LB) is associated with a range of cognitive, motor, neuropsychiatric, sleep, autonomic,…”
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Neuronal Loss and Α-Synuclein Pathology in the Superior Colliculus and Its Relationship to Visual Hallucinations in Dementia with Lewy Bodies by Erskine, Daniel, M.Res, Thomas, Alan J., Ph.D., M.R.C.Psych, Taylor, John-Paul, Ph.D., M.R.C.Psych, Savage, Michael A., M.Res, Attems, Johannes, M.D, McKeith, Ian G., Ph.D., F.Med.Sci, Morris, Christopher M., Ph.D, Khundakar, Ahmad A., Ph.D

“…Objective Patients with dementia with Lewy bodies (DLB) often experience visual hallucinations, which are related to decreased quality of life for patients and…”
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Glucocerebrosidase Mutations alter the endoplasmic reticulum and lysosomes in Lewy body disease by Kurzawa-Akanbi, Marzena, Hanson, Peter S, Blain, Peter G, Lett, Debra J, McKeith, Ian G, Chinnery, Patrick F, Morris, Christopher M

“…J. Neurochem. (2012) 123, 298–309. Lewy body disease (LBD) development is enhanced by mutations in the GBA gene coding for glucocerebrosidase (GCase). The…”
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Consecutive sessions of transcranial direct current stimulation do not remediate visual hallucinations in Lewy body dementia: a randomised controlled trial by Elder, Greg J, Colloby, Sean J, Firbank, Michael J, McKeith, Ian G, Taylor, John-Paul

“…Complex visual hallucinations are common in Lewy body dementia (LBD) and can cause significant patient and caregiver distress. Current treatments are primarily…”
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The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts by Myers, Amanda J, Pittman, Alan M, Zhao, Alice S, Rohrer, Kristen, Kaleem, Mona, Marlowe, Lauren, Lees, Andrew, Leung, Doris, McKeith, Ian G, Perry, Robert H, Morris, Chris M, Trojanowski, John Q, Clark, Christopher, Karlawish, Jason, Arnold, Steve, Forman, Mark S, Van Deerlin, Vivianna, de Silva, Rohan, Hardy, John

“…Abstract Previously we have shown that the H1c haplotype on the background of the H1 clade of haplotypes at the MAPT locus is associated with increased risk…”
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Early Cognitive Change in the General Population: How Do Different Definitions Work? by Stephan, Blossom C. M., Matthews, Fiona E., McKeith, Ian G., Bond, John, Brayne, Carol

“…OBJECTIVES: To explore the application of existing classifications of mild cognitive impairment (MCI) and associated states in a large population sample…”
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Clinical diagnosis of Lewy body dementia by Surendranathan, Ajenthan, Kane, Joseph P. M., Bentley, Allison, Barker, Sally A. H., Taylor, John-Paul, Thomas, Alan J., Allan, Louise M., McNally, Richard J., James, Peter W., McKeith, Ian G., Burn, David J., O'Brien, John T.

“…Lewy body dementia, consisting of both dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD), is considerably under-recognised clinically…”
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Cognitive Decline and Dementia Risk in Older Adults With Psychotic Symptoms: A Prospective Cohort Study by Köhler, Sebastian, Ph.D, Allardyce, Judith, M.D., Ph.D, Verhey, Frans R.J., M.D., Ph.D, McKeith, Ian G., M.D, Matthews, Fiona, Ph.D, Brayne, Carol, M.D, Savva, George M., Ph.D

“…Objectives To study the temporal association between psychotic symptoms with cognitive decline and incident dementia. Design Population-based prospective…”
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Pathological correlates of frontotemporal lobar degeneration in the elderly by Baborie, Atik, Griffiths, Timothy D., Jaros, Evelyn, McKeith, Ian G., Burn, David J., Richardson, Anna, Ferrari, Raffaele, Moreno, Jorge, Momeni, Parastoo, Duplessis, Daniel, Pal, Piyali, Rollinson, Sara, Pickering-Brown, Stuart, Thompson, Jennifer C., Neary, David, Snowden, Julie S., Perry, Robert, Mann, David M. A.

“…Frontotemporal lobar degeneration (FTLD) is generally recognised as a disorder with presenile onset (that is before 65 years of age) with only occasional cases…”
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Rivastigmine in the treatment of parkinsonian psychosis and cognitive impairment: Preliminary findings from an open trial by Reading, Paul J., Luce, Anna K, McKeith, Ian G.

“…This open study assessed the ability of rivastigmine to treat the neuropsychiatric complications of advanced Parkinson's disease. In a group of 12 patients,…”
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Author response: Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium by McKeith, Ian G

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TDP‐43 pathology in Alzheimer's disease, dementia with Lewy bodies and ageing by McAleese, Kirsty E., Walker, Lauren, Erskine, Daniel, Thomas, Alan J., McKeith, Ian G., Attems, Johannes

“…Intracellular inclusions consisting of TAR DNA binding protein‐43 (TDP‐43 pathology) are present in up to 57% of Alzheimer's disease (AD) cases and follow a…”
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New evidence on the management of Lewy body dementia by Taylor, John-Paul, McKeith, Ian G, Burn, David J, Boeve, Brad F, Weintraub, Daniel, Bamford, Claire, Allan, Louise M, Thomas, Alan J, O'Brien, John T

“…Dementia with Lewy bodies and Parkinson's disease dementia, jointly known as Lewy body dementia, are common neurodegenerative conditions. Patients with Lewy…”
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The clinical characteristics of dementia with Lewy bodies and a consideration of prodromal diagnosis by Donaghy, Paul C, McKeith, Ian G

“…Dementia with Lewy bodies (DLB) is the second most common type of degenerative dementia following Alzheimer's disease (AD). DLB is clinically and…”
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