Search Results - "McKee, Marian L."
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Reduction of Furin-Nicked Pseudomonas Exotoxin A: An Unfolding Story
Published in Biochemistry (Easton) (14-12-1999)“…Upon entering mammalian cells, Pseudomonas exotoxin A (PE) is proteolytically processed by furin to produce an N-terminal fragment of 28 kDa and a C-terminal…”
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Mitigating the risk of Zika virus contamination of raw materials and cell lines in the manufacture of biologicals
Published in Journal of general virology (01-02-2018)“…Ensuring the virological safety of biologicals is challenging due to the risk of viral contamination of raw materials and cell banks, and exposure during…”
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Multiplex PCR for species-level identification of Bacillus anthracis and detection of pXO1, pXO2, and related plasmids
Published in Health security (01-04-2015)“…The Bacillus anthracis virulence plasmids pXO1 and pXO2 have critical implications for biosafety and select agent status. The proper identification and…”
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Arginine-dependent acid-resistance pathway in Shigella boydii
Published in Archives of microbiology (01-03-2011)“…Ability to survive the low pH of the human stomach is considered be an important virulent determinant. It was suggested that the unique acid tolerance of…”
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Size-based separations as an important discriminator in development of proximity ligation assays for protein or organism detection
Published in Electrophoresis (01-05-2010)“…Proximity ligation is a powerful technique to measure minute concentrations of target protein with high specificity, and it has been demonstrated to be…”
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Reclassification of the Listeria-CAMP test strain ATCC 49444 Staphylococcus aureus as Staphylococcus pseudintermedius
Published in Journal of food protection (01-08-2010)“…ATCC 49444, originally designated as Staphylococcus aureus, has been cited as a component strain in the CAMP test for identification of Listeria monocytogenes…”
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The case for developing consensus standards for research in microbial pathogenesis: Bacillus anthracis toxins as an example
Published in Infection and immunity (01-10-2009)Get full text
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Mammalian cell expression of an active site mutant of Pseudomonas exotoxin disrupts LRP1 maturation
Published in Journal of biomedical science (01-07-2008)“…Low density lipoprotein receptor-related protein 1, (LRP1) is a large multifunctional receptor that binds more than 25 physiologic ligands. In addition, it…”
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Bacterial toxins as tools for mucosal vaccination
Published in Drug Discovery Today (15-02-2002)“…Several studies have demonstrated that the biological properties of secreted bacterial toxins could be harnessed for the induction of mucosal and systemic…”
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Book Review Journal Article -
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Epithelial application of Pseudomonas aeruginosa exotoxin A results in a selective targeting to cells in the liver, spleen and lymph node
Published in Journal of controlled release (01-03-2000)“…Pseudomonas aeruginosa exotoxin A (PE) is a 67-kDa protein expressed under the selective pressure of a low iron environment. Previous studies using non-toxic…”
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Journal Article Conference Proceeding -
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Characterization of V3 Loop-Pseudomonas Exotoxin Chimeras
Published in The Journal of biological chemistry (17-04-1998)“…To develop a candidate vaccine for human immunodeficiency virus, type 1 (HIV-1), chimeric proteins were constructed by inserting sequences derived from the V3…”
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The role of the eae gene of enterohemorrhagic Escherichia coli in intimate attachment in vitro and in a porcine model
Published in The Journal of clinical investigation (01-09-1993)“…The eaeA gene of enteropathogenic Escherichia coli (EPEC) is necessary for intimate attachment to epithelial cells in vitro. Enterohemorrhagic E. coli (EHEC)…”
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Truncated enterohemorrhagic Escherichia coli (EHEC) O157:H7 intimin (EaeA) fusion proteins promote adherence of EHEC strains to HEp-2 cells
Published in Infection and Immunity (01-06-1996)“…Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Characterization of V3 loop-Pseudomonas exotoxin chimeras. Candidate vaccines for human immunodeficiency virus-1
Published in The Journal of biological chemistry (17-04-1998)“…To develop a candidate vaccine for human immunodeficiency virus, type 1 (HIV-1), chimeric proteins were constructed by inserting sequences derived from the V3…”
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Heterologous gene expression in Bacteroides fragilis
Published in Plasmid (01-03-1992)“…Bacteroides fragilis and other gastrointestinal tract Bacteroides are unusual gram-negative eubacteria in that genes from other gram-negative eubacteria are…”
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