Search Results - "McKee, Laurel A.K."

Sexually dimorphic myofilament function and cardiac troponin I phosphospecies distribution in hypertrophic cardiomyopathy mice by McKee, Laurel A.K., Chen, Hao, Regan, Jessica A., Behunin, Samantha M., Walker, Jeffery W., Walker, John S., Konhilas, John P.

“…► 10–12Month HCM females develop proportionately larger hearts than HCM males. ► HCM females display alterations in Ca2+-sensitivity over female WT; HCM males…”
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LKB1/Mo25/STRAD Uniquely Impacts Sarcomeric Contractile Function and Posttranslational Modification by Behunin, Samantha M., Lopez-Pier, Marissa A., Birch, Camille L., McKee, Laurel A.K., Danilo, Christiane, Khalpey, Zain, Konhilas, John P.

“…The myocardium undergoes extensive metabolic and energetic remodeling during the progression of cardiac disease. Central to remodeling are changes in the…”
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Micro-RNA-195 and -451 regulate the LKB1/AMPK signaling axis by targeting MO25 by Chen, Hao, Untiveros, Gustavo M, McKee, Laurel A K, Perez, Jessica, Li, Jing, Antin, Parker B, Konhilas, John P

“…Recently, MicroRNAs (miR) and AMP-kinase (AMPK) have emerged as prominent players in the development of cardiac hypertrophy and heart failure. We hypothesized…”
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Temporal and morphological impact of pressure overload in transgenic FHC mice by Chen, Hao, Hwang, Hyosook, McKee, Laurel A K, Perez, Jessica N, Regan, Jessica A, Constantopoulos, Eleni, Lafleur, Bonnie, Konhilas, John P

“…Although familial hypertrophic cardiomyopathy (FHC) is characterized as cardiac disease in the absence of overt stressors, disease penetrance, and pathological…”
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Temporal and morphological impact of pressure overload in R403Q mutant mice by Hao eChen, Hyosook eHwang, Laurel A.K. McKee, Jessica N Perez, Jessica A Regan, Eleni eConstantopoulos, Bonnie eLaFleur, John Peter Konhilas

“…Although familial hypertrophic cardiomyopathy (FHC) is characterized as cardiac disease in the absence of overt stressors, disease penetrance and pathological…”
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