Search Results - "McKEOWN, P."
-
1
Heritable epigenetic diversity for conservation and utilization of epigenetic germplasm resources of clonal East African Highland banana (EAHB) accessions
Published in Theoretical and applied genetics (01-09-2020)“…Key message Genetically identical East African Highland banana (EAHB) clones are epigenetically diverse with heritable epialleles that can contribute to…”
Get full text
Journal Article -
2
Synthesis and Pro-Apoptotic Effects of Nitrovinylanthracenes and Related Compounds in Chronic Lymphocytic Leukaemia (CLL) and Burkitt's Lymphoma (BL)
Published in Molecules (Basel, Switzerland) (14-12-2023)“…Chronic lymphocytic leukaemia (CLL) is a malignancy of the immune B lymphocyte cells and is the most common leukaemia diagnosed in developed countries. In this…”
Get full text
Journal Article -
3
Spatiotemporal epidemiology of cryptosporidiosis in the Republic of Ireland, 2008–2017: development of a space–time “cluster recurrence” index
Published in BMC infectious diseases (28-08-2021)“…Abstract Background Ireland frequently reports the highest annual Crude Incidence Rates (CIRs) of cryptosporidiosis in the EU, with national CIRs up to ten…”
Get full text
Journal Article -
4
Vitamins Reverse Endothelial Dysfunction Through Regulation of eNOS and NAD(P)H Oxidase Activities
Published in Hypertension (Dallas, Tex. 1979) (01-03-2003)“…ABSTRACT—Antioxidant vitamins C and E have protective properties in genetic hypertension associated with enhanced oxidative stress. This study investigated…”
Get full text
Journal Article -
5
Association of TGFB1 rs1800469 and BCMO1 rs6564851 with coronary heart disease and IL1B rs16944 with all-cause mortality in men from the Northern Ireland PRIME study
Published in PloS one (22-08-2022)“…Historically, high levels of morbidity and mortality have been associated with cardiovascular disease in the Northern Ireland population. Previously reported…”
Get full text
Journal Article -
6
A High Polyphenol Diet Improves Psychological Well-Being: The Polyphenol Intervention Trial (PPhIT)
Published in Nutrients (14-08-2020)“…Mental ill health is currently one of the leading causes of disease burden worldwide. A growing body of data has emerged supporting the role of diet,…”
Get full text
Journal Article -
7
The Role of Micronutrients in Heart Failure
Published in Journal of the Academy of Nutrition and Dietetics (01-06-2012)“…Abstract Heart failure is a common condition in the Western world, particularly among elderly persons and with an ever-aging population, the incidence is…”
Get full text
Journal Article -
8
Verotoxigenic Escherichia coli transmission in Ireland: a review of notified outbreaks, 2004–2012
Published in Epidemiology and infection (01-04-2016)“…Verotoxigenic Escherichia coli (VTEC) are significant for their low infectious dose, their potential clinical severity and the frequency with which they…”
Get full text
Journal Article -
9
Analysis of Integrated Virological and Epidemiological Reports of Norovirus Outbreaks Collected within the Foodborne Viruses in Europe Network from 1 July 2001 to 30 June 2006
Published in Journal of Clinical Microbiology (01-09-2008)“…The Foodborne Viruses in Europe network has developed integrated epidemiological and virological outbreak reporting with aggregation and sharing of data…”
Get full text
Journal Article -
10
Educational interventions in neurology: a comprehensive systematic review
Published in European journal of neurology (01-07-2013)“…A fear of neurology and neural sciences (neurophobia) may have clinical consequences. There is therefore a need to formulate an evidence‐based approach to…”
Get full text
Journal Article -
11
Impaired activities of antioxidant enzymes elicit endothelial dysfunction in spontaneous hypertensive rats despite enhanced vascular nitric oxide generation
Published in Cardiovascular research (01-08-2003)“…Enhanced oxidative stress is involved in mediating the endothelial dysfunction associated with hypertension. The aim of this study was to investigate the…”
Get full text
Journal Article -
12
Socio-economic factors associated with the incidence of Shiga-toxin producing Escherichia coli (STEC) enteritis and cryptosporidiosis in the Republic of Ireland, 2008–2017
Published in Epidemiology and infection (2021)“…The Republic of Ireland (ROI) currently reports the highest incidence rates of Shiga-toxin producing Escherichia coli (STEC) enteritis and cryptosporidiosis in…”
Get full text
Journal Article -
13
Whole genome sequencing provides an unambiguous link between Salmonella Dublin outbreak strain and a historical isolate
Published in Epidemiology and infection (01-02-2016)“…Salmonella enterica subsp. enterica serovar Dublin is an uncommon cause of human salmonellosis; however, a relatively high proportion of cases are associated…”
Get full text
Journal Article -
14
Synthesis and Biochemical Evaluation of Ethanoanthracenes and Related Compounds: Antiproliferative and Pro-Apoptotic Effects in Chronic Lymphocytic Leukemia (CLL)
Published in Pharmaceuticals (Basel, Switzerland) (05-08-2024)“…Chronic lymphocytic leukemia (CLL) is a malignancy of mature B cells, and it is the most frequent form of leukemia diagnosed in Western countries. It is…”
Get full text
Journal Article -
15
Exercise training improves activity in adolescents with congenital heart disease
Published in Heart (British Cardiac Society) (01-08-2013)“…To ascertain if motivational techniques and a structured exercise programme can increase activity in adolescents afflicted with congenital heart disease (CHD)…”
Get more information
Journal Article -
16
Assessment of aspirin resistance varies on a temporal basis in patients with ischaemic heart disease
Published in Heart (British Cardiac Society) (01-08-2009)“…Laboratory tests including optical platelet aggregometry (OPA), platelet function analyser (PFA-100), and thromboxane B2 (TXB2) metabolite levels have been…”
Get more information
Journal Article -
17
Investigation of a foodborne outbreak of Shigella sonnei in Ireland and Northern Ireland, December 2016: the benefits of cross-border collaboration and commercial sales data
Published in Public health (London) (01-05-2020)“…To describe a cross-border foodborne outbreak of Shigella sonnei that occurred in Ireland and Northern Ireland (NI) in December 2016 whilst also highlighting…”
Get full text
Journal Article -
18
Exercise prescription improves exercise tolerance in young children with CHD: a randomised clinical trial
Published in Open heart (14-05-2021)“…ObjectiveThe main objective of this study was to ascertain if a structured intervention programme can improve the biophysical health of young children with…”
Get full text
Journal Article -
19
Leptospirosis in Ireland: annual incidence and exposures associated with infection
Published in Epidemiology and infection (01-04-2014)“…Human leptospirosis is found throughout the world, albeit with a higher incidence in tropical regions. In temperate regions it is associated with certain…”
Get full text
Journal Article -
20
‘Why didn’t they see my scars?’ Critical thematic analysis of simulated participants’ perceived tensions surrounding objective structured clinical examinations
Published in Advances in simulation (London) (21-08-2021)“…Abstract Background Simulated participants (SPs) play an important role in simulated assessments of clinical encounters between medical students and patients,…”
Get full text
Journal Article