Search Results - "McKELLAR, Q. A."

Pharmacokinetic/pharmacodynamic relationships of antimicrobial drugs used in veterinary medicine by McKellar, Q.A, Sanchez Bruni, S.F, Jones, D.G

“…The rise in incidence of antimicrobial resistance, consumer demands and improved understanding of antimicrobial action has encouraged international agencies to…”
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Pharmacokinetic–pharmacodynamic integration and modelling of oxytetracycline administered alone and in combination with carprofen in calves by Brentnall, C., Cheng, Z., McKellar, Q.A., Lees, P.

“…The pharmacokinetic (PK) and pharmacodynamic (PD) profiles of oxytetracycline were investigated, when administered both alone and in the presence of carprofen,…”
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The genetic control of IgA activity against Teladorsagia circumcincta and its association with parasite resistance in naturally infected sheep by Strain, S A J, Bishop, S C, Henderson, N G, Kerr, A, McKellar, Q A, Mitchell, S, Stear, M J

“…Previous studies in deliberately infected sheep have shown an association between IgA activity against 4th-stage larvae of Teladorsagia circumcincta and…”
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Fenbendazole Pharmacokinetics, Metabolism, and Potentiation in Horses by MCKELLAR, Q. A, GOKBULUT, C, MUZANDU, K, BENCHAOUI, H

“…The present study was designed to describe the pharmacokinetics and fecal excretion of fenbendazole (FBZ) and fenbendazole sulphoxide (FBZSO) and their…”
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Eosinophilia as a marker of resistance to Teladorsagia circumcincta in Scottish Blackface lambs by Stear, M J, Henderson, N G, Kerr, A, McKellar, Q A, Mitchell, S, Seeley, C, Bishop, S C

“…Faecal egg counts and peripheral blood eosinophil counts were taken from Scottish Blackface lambs following natural, predominantly Teladorsagia circumcincta…”
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Ecotoxicology and residues of anthelmintic compounds by McKellar, Q.A.

“…Anthelmintics and endectocides used for the treatment and prophylaxis of Ostertagia sp. in ruminants include benzimidazoles, levamisole, morantel and the…”
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Avermectins and milbemycins by McKellar, Q A, Benchaoui, H A

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How hosts control worms by Stear, M. J, Bairden, K, Duncan, J. L, Holmes, P. H, McKellar, Q. A, Park, M, Strain, S, Murray, M, Bishop, S. C, Gettinby, G

“…Nematodes are a major cause of disease and death in humans, domestic animals and wildlife. Understanding why some individuals suffer severely whereas others…”
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An ovine Major histocompatibility complex DRB1 allele is associated with low faecal egg counts following natural, predominantly Ostertagia circumcincta infection by Schwaiger, F.-W., Gostomski, D., Stear, M.J., Duncan, J.L., McKellar, Q.A., Epplen, J.T., Buitkamp, J.

“…Infection with Ostertagia circumcincta is a major constraint on sheep production in temperate areas of the world. A potential control strategy is the use of…”
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Plasma pharmacokinetics and faecal excretion of ivermectin, doramectin and moxidectin following oral administration in horses by GOKBULUT, C., NOLAN, A. M., MCKELLAR, Q. A.

“…Summary The present study was carried out to investigate whether the pharmacokinetics of avermectins or a milbemycin could explain their known or predicted…”
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Pharmacodynamics of oxytetracycline administered alone and in combination with carprofen in calves by Brentnall, C., Cheng, Z., McKellar, Q. A., Lees, P.

“…The pharmacodynamics (PD) of oxytetracycline was investigated against a strain of Mannheimia haemolytica. In vitro measurements, comprising minimum inhibitory…”
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The processes influencing the distribution of parasitic nematodes among naturally infected lambs by Stear, M J, Bairden, K, Bishop, S C, Gettinby, G, McKellar, Q A, Park, M, Strain, S, Wallace, D S

“…The impact of mixed, nematode infection upon a group of animals will depend upon the number of nematodes present, how they are distributed among hosts and…”
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Antimicrobial resistance: a veterinary perspective by McKellar, Q A

“…The short generation time and ability to exchange genetic material has inevitably resulted in the development of resistance to antimicrobials by many animal…”
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Regulation of egg production, worm burden, worm length and worm fecundity by host responses in sheep infected with Ostertagia circumcincta by Stear, M J, Bishop, S C, Doligalska, M, Duncan, J L, Holmes, P H, Irvine, J, McCririe, L, McKellar, Q A, Sinski, E, Murray, M

“…Following infection with Ostertagia circumcincta there was considerable variation in worm burdens, worm size and number of inhibited larvae even among sheep…”
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Influence of oxytetracycline on carprofen pharmacodynamics and pharmacokinetics in calves by Brentnall, C., Cheng, Z., Mckellar, Q. A., Lees, P.

“…A tissue cage model of inflammation in calves was used to determine the pharmacokinetic and pharmacodynamic properties of individual carprofen enantiomers,…”
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Interaction between Fenbendazole and Piperonyl Butoxide: Pharmacokinetic and Pharmacodynamic Implications by Benchaoui, H. A., Mckellar, Q. A.

“…The effect of the cytochrome P450 inhibitor, piperonyl butoxide on the pharmacokinetics and anthelmintic efficacy of the benzimidazole compound fenbendazole…”
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Changes to oxfendazole chiral kinetics and anthelmintic efficacy induced by piperonyl butoxide in horses by BRUNI, S. F. SÁNCHEZ, FUSÉ, L. A., MORENO, L., SAUMELL, C. A., ÁLVAREZ, L. I., FIEL, C., McKELLAR, Q. A., LANUSSE, C. E.

“…Summary Reasons for performing the study: The study of novel pharmacological strategies to control parasitism in horses is required since many parasite species…”
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Comparative plasma disposition of fenbendazole, oxfendazole and albendazole in dogs by Gokbulut, C., Bilgili, A., Hanedan, B., McKellar, Q.A.

“…The plasma disposition of fenbendazole (FBZ), oxfendazole (OFZ) and albendazole (ABZ); and the enantiospecific disposition of OFZ, and ABZSO produced were…”
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Dexamethasone decreases plasma levels of the prochiral fenbendazole and its chiral and achiral metabolites in sheep by Sánchez, S., Small, J., Jones, D. G., McKellar, Q. A.

“…1. The effect of co-administration of either short- or long-acting formulations of DXM on hepatic function and the plasma pharmacokinetic behaviour of…”
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The benzimidazole anthelmintic agents--a review by McKellar, Q A, Scott, E W

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