Search Results - "McIntyre, Deborah"

Sleep disorders in Parkinson's disease: Many causes, few therapeutic options by Diederich, Nico J, McIntyre, Deborah J

“…Abstract Sleep symptoms in Parkinson's disease (PD) are frequent and have multifactorial and multilayered causes. Primary involvement of sleep/wake regulating…”
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Early On-Treatment Assessment of T Cells, Cytokines, and Tumor DNA with Adaptively Dosed Nivolumab + Ipilimumab: Final Results from the Phase 2 ADAPT-IT Study by Smithy, James W, Kalvin, Hannah L, Ehrich, Fiona D, Shah, Ronak, Adamow, Matthew, Raber, Vladislav, Maher, Collen A, Kleman, Jenna, McIntyre, Deborah A G, Shoushtari, Alexander N, Betof Warner, Allison, Callahan, Margaret K, Momtaz, Parisa, Eton, Omar, Nair, Suresh, Wolchok, Jedd D, Chapman, Paul B, Berger, Michael F, Panageas, Katherine S, Postow, Michael A

“…The Adaptively Dosed ImmunoTherapy Trial (ADAPT-IT;NCT03122522) investigated adaptive ipilimumab discontinuation in melanoma based on early radiographic…”
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Luxembourg Parkinson's study -comprehensive baseline analysis of Parkinson's disease and atypical parkinsonism by Pavelka, Lukas, Rawal, Rajesh, Ghosh, Soumyabrata, Pauly, Claire, Pauly, Laure, Hanff, Anne-Marie, Kolber, Pierre Luc, Jónsdóttir, Sonja R, Mcintyre, Deborah, Azaiz, Kheira, Thiry, Elodie, Vilasboas, Liliana, Soboleva, Ekaterina, Giraitis, Marijus, Tsurkalenko, Olena, Sapienza, Stefano, Diederich, Nico, Klucken, Jochen, Glaab, Enrico, Aguayo, Gloria A, Jubal, Eduardo Rosales, Perquin, Magali, Vaillant, Michel, May, Patrick, Gantenbein, Manon, Satagopam, Venkata P, Krüger, Rejko

“…Deep phenotyping of Parkinson's disease (PD) is essential to investigate this fastest-growing neurodegenerative disorder. Since 2015, over 800 individuals with…”
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ISO 17025: Practical benefits of implementing a quality system by HONSA, Julie D, MCINTYRE, Deborah A

“…As a laboratory certified to ISO 9001:2000 and accredited to ISO 17025, rtech laboratories has incorporated an overall system for technical and quality…”
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Propagative α-synuclein seeds as serum biomarkers for synucleinopathies by Okuzumi, Ayami, Hatano, Taku, Matsumoto, Gen, Nojiri, Shuko, Ueno, Shin-ichi, Imamichi-Tatano, Yoko, Kimura, Haruka, Kakuta, Soichiro, Kondo, Akihide, Fukuhara, Takeshi, Li, Yuanzhe, Funayama, Manabu, Saiki, Shinji, Taniguchi, Daisuke, Tsunemi, Taiji, McIntyre, Deborah, Gérardy, Jean-Jacques, Mittelbronn, Michel, Kruger, Rejko, Uchiyama, Yasuo, Nukina, Nobuyuki, Hattori, Nobutaka

“…Abnormal α-synuclein aggregation is a key pathological feature of a group of neurodegenerative diseases known as synucleinopathies, which include Parkinson’s…”
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Continuous Levodopa Delivery with an Intraoral Micropump System: An Open‐Label Pharmacokinetics and Clinical Study by Olanow, C. Warren, McIntyre, Deborah, Matarazzo, Michele, Leinonen, Mika, McGarry, Andrew, Kamp, Cornelia, Kennedy, Julie, Torti, Margherita, Kruger, Rejko, Obeso, José A., Stocchi, Fabrizio, Heller, Ephraim, Kieburtz, Karl

“…Background Double‐blind studies have demonstrated that motor complications in Parkinson's disease (PD) can be reduced with continuous delivery of levodopa. The…”
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Experiences of adults with high-care needs and their family members with housing and support pathways in Australia by McIntyre, Deborah, Fleming, Jennifer, Foster, Michele, Tweedy, Sean

“…Purpose: Many adults aged less than 65 years with high-care needs resulting from acquired disabilities are unable to access age-appropriate housing and…”
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Prolonged Somnolence in Alcoholic Patients with Epilepsy: A Case Report by Saleh, Christian, McIntyre, Deborah, Beyenburg, Stefan

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PERSONALIZED DEMENTIA PREVENTION IN LUXEMBOURG: INSIGHTS INTO THE PROGRAMME DEMENTIA PREVENTION (PDP) by Schröder, Valerie, Skrozic, Amna, Erz, Dorothee, Kaysen, Anne, Fritz, Joëlle, Loureiro, Joao, McIntyre, Deborah, Krueger, Rejko

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Programme Dementia Prevention (pdp): A Nationwide Program for Personalized Prevention in Luxembourg by Schröder, Valerie E, Skrozic, Amna, Erz, Dorothee, Kaysen, Anne, Fritz, Joëlle V, Loureiro, Joao M, McIntyre, Deborah, Pauly, Laure, Kemp, Jennifer, Schmitz, Sabine K, Wagner, Sophie, Reyes, Margarita, Soare, Ruxandra, Satagopam, Venkata, Vega, Carlos, Gawron, Piotr, Roomp, Kirsten, Conde, Patricia Martins, Klucken, Jochen, Köhler, Sebastian, Hartmann, Tobias, Dodel, Richard, Leist, Anja K, Kalbe, Elke, Krüger, Rejko

“…With continuously aging societies, an increase in the number of people with cognitive decline is to be expected. Aside from the development of causative…”
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Dopamine Pathway and Parkinson's Risk Variants Are Associated with Levodopa‐Induced Dyskinesia by Ferwerda, Bart, Tocino, Maria T.P., Belloso, Dìaz R., Gómez‐Garre, Pilar, Faouzi, Johann, Taba, Pille, Pavelka, Lukas, Gomes, Clarissa P.C., May, Patrick, Milanowski, Lukasz M., Uitti, Ryan J., Heutink, Peter, Eberly, Shirley, Alvarez, Ignacio, Krohn, Lynne, Ruskey, Jennifer A., Asayesh, Farnaz, Ross, Owen A., Krüger, Rejko, Corvol, Jean‐Christophe, Koks, Sulev, De Bie, Rob M.A., Acharya, Geeta, Aguayo, Gloria, Alexandre, Myriam, Ali, Muhammad, Ammerlann, Wim, Beaumont, Katy, Becker, Regina, Bellora, Camille, Berg, Daniela, Calme, Jessica, Castillo, Lorieza, Contesotto, Gessica, Diederich, Nico, Fagherazzi, Guy, Ferrand, Jean‐Yves, Gantenbein, Manon, Gasser, Thomas, Gawron, Piotr, Ghosh, Soumyabrata, Giraitis, Marijus, Graas, Jérôme, Graziano, Mariella, Grünewald, Anne, Gu, Wei, Hammot, Gaël, Hanff, Anne‐Marie, Heneka, Michael, Henr, Estelle, Herzinger, Sascha, Heymann, Michael, Hundt, Alexander, Lebioda, Jacek Jaroslaw, Jaroz, Yohan, Jónsdóttir, Sonja, Klucken, Jochen, Krüger, Rejko, Lambert, Pauline, Liszka, Robert, Lorentz, Victoria, Lupu, Paula Cristina, Marques, Tainá M., Mackay, Clare, Maetzler, Walter, Marcus, Katrin, Marques, Guilherme, Conde, Patricia Martins, May, Patrick, Mediouni, Chouaib, Meisch, Francoise, Menster, Myriam, Minelli, Maura, Mittelbronn, Michel, Mollenhauer, Brit, Mühlschlegel, Friedrich, Nehrbass, Ulf, Nicolai, Beatrice, Nicolay, Jean‐Paul, Noor, Fozia, Ostaszewski, Marek, Pachchek, Sinthuja, Pauly, Claire, Lima, Rosalina Ramos, Rawal, Rajesh, Bobbili, Dheeraj Reddy, Roomp, Kirsten, Rosety, Isabel, Satagopam, Venkata, Schmitz, Sabine, Schwamborn, Jens, Sharify, Amir, Soboleva, Ekaterina, Loo, Rebecca Ting Jiin, Trouet, Johanna, Valenti, Mesele, Vega, Carlos, Wade‐Martins, Richard, Wollscheid‐Lengeling, Evi, Zelimkhanov, Gelani

“…Background Levodopa‐induced dyskinesia (LID) is a common adverse effect of levodopa, one of the main therapeutics used to treat the motor symptoms of…”
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Mixed effects models but not t-tests or linear regression detect progression of apathy in Parkinson's disease over seven years in a cohort: a comparative analysis by Hanff, Anne-Marie, Krüger, Rejko, McCrum, Christopher, Ley, Christophe

“…While there is an interest in defining longitudinal change in people with chronic illness like Parkinson's disease (PD), statistical analysis of longitudinal…”
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Levodopa-induced dyskinesia in Parkinson's disease: Insights from cross-cohort prognostic analysis using machine learning by Loo, Rebecca Ting Jiin, Klucken, Jochen, Khoury, Fouad, Vidailhet, Marie, Krüger, Rejko, Acharya, Geeta, Alexandre, Myriam, Ali, Muhammad, Ammerlann, Wim, Arena, Giuseppe, Batutu, Roxane, Béchet, Sibylle, Berchem, Guy, Bisdorff, Alexandre, Boussaad, Ibrahim, Bouvier, David, Castillo, Lorieza, Contesotto, Gessica, DE Bremaeker, Nancy, Dewitt, Brian, Diederich, Nico, Dondelinger, Rene, Ramia, Nancy E., Ferrari, Angelo, Frauenknecht, Katrin, Fritz, Joëlle, Gantenbein, Manon, Gawron, Piotr, Georges, Laura, Ghosh, Soumyabrata, Giraitis, Marijus, Goergen, Martine, Gómez DE Lope, Elisa, Graas, Jérôme, Graziano, Mariella, Groues, Valentin, Grünewald, Anne, Hammot, Gaël, Anne-Marie, H.A.N.F.F., Hansen, Linda, Heneka, Michael, Henry, Estelle, Henry, Margaux, Herbrink, Sylvia, Hundt, Alexander, Jónsdóttir, Sonja, Klucken, Jochen, Kofanova, Olga, Krüger, Rejko, Lambert, Pauline, Landoulsi, Zied, Lentz, Roseline, Longhino, Laura, Lopes, Ana Festas, Lorentz, Victoria, Marques, Guilherme, Martins Conde, Patricia, Patrick, M.A.Y., Mcintyre, Deborah, Mediouni, Chouaib, Meisch, Francoise, Mendibide, Alexia, Menster, Myriam, Minelli, Maura, Mittelbronn, Michel, Mtimet, Saïda, Nati, Romain, Nickels, Sarah, Nicolai, Beatrice, Jean-Paul, N.I.C.O.L.A.Y., Gomes, Clarissa P.C., Pauly, Claire, Pauly, Laure, Pavelka, Lukas, Perquin, Magali, Pexaras, Achilleas, Rauschenberger, Armin, Rawal, Rajesh, Remark, Lucie, Richard, Ilsé, Roland, Olivia, Rosales, Eduardo, Sapienza, Stefano, Satagopam, Venkata, Schmitz, Sabine, Schneider, Reinhard, Schwamborn, Jens, Sharify, Amir, Soare, Ruxandra, Soboleva, Ekaterina, Sokolowska, Kate, Theresine, Maud, Thien, Hermann, Thiry, Elodie, Ting Jiin Loo, Rebecca, Trouet, Johanna, Vaillant, Michel, Vilas Boas, Liliana, Wilmes, Paul, Wollscheid-Lengeling, Evi

“…Prolonged levodopa treatment in Parkinson's disease (PD) often leads to motor complications, including levodopa-induced dyskinesia (LID). Despite continuous…”
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Cardiovascular history and risk of idiopathic Parkinson's disease: a cross-sectional observational study by Acharya, Shubhra, Lumley, Andrew I, Devaux, Yvan

“…Parkinson's disease (PD), while often associated with its distinctive motor symptoms, can also exert a notable impact on the cardiovascular system due to the…”
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Letter from Luxembourg by Beyenburg, Stefan, McIntyre, Deborah

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Preferences regarding Disclosure of Risk for Parkinson's Disease in a Population‐based Study by Mahlknecht, Philipp, Leiter, Simon, Horlings, Corinne, Schwarzová, Katarína, Egner, Iris, Stockner, Heike, Marini, Kathrin, Theyer, Christoph, Zamarian, Laura, Djamshidian, Atbin, Seppi, Klaus, Farfan, Fernanda, Garrido, Alicia, Ghosh, Soumyabrata, Krüger, Rejko, McIntyre, Deborah, Mollenhauer, Brit, Noyce, Alastair, Pauly, Claire, Pilco‐Janeta, Daniel F., Rege, Kavita, Satagopam, Venkata P., Schade, Sebastian, Simonet, Cristina, Trenkwalder, Claudia, Poewe, Werner

“…Preferences for risk disclosure in population-based studies assessing Parkinson's disease (PD) risk have not been assessed so far.BACKGROUNDPreferences for…”
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TECRA Unique test for rapid detection of Salmonella in food: collaborative study by Hughes, D, Dailianis, A E, Hill, L, McIntyre, D A, Anderson, A

“…The TECRA Unique Salmonella test uses the principle of immunoenrichment to allow rapid detection of Salmonellae in food. A collaborative study was conducted to…”
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Accurate long-read sequencing identified GBA1 as major risk factor in the Luxembourgish Parkinson’s study by Pachchek, Sinthuja, Landoulsi, Zied, Pavelka, Lukas, Schulte, Claudia, Buena-Atienza, Elena, Gross, Caspar, Hauser, Ann-Kathrin, Reddy Bobbili, Dheeraj, Casadei, Nicolas, May, Patrick, Krüger, Rejko

“…Heterozygous variants in the glucocerebrosidase GBA1 gene are an increasingly recognized risk factor for Parkinson’s disease (PD). Due to the GBAP1 pseudogene,…”
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Comprehensive blood metabolomics profiling of Parkinson’s disease reveals coordinated alterations in xanthine metabolism by de Lope, Elisa Gómez, Loo, Rebecca Ting Jiin, Rauschenberger, Armin, Ali, Muhammad, Pavelka, Lukas, Marques, Tainá M., Gomes, Clarissa P. C., Krüger, Rejko, Glaab, Enrico

“…Parkinson’s disease (PD) is a highly heterogeneous disorder influenced by several environmental and genetic factors. Effective disease-modifying therapies and…”
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Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome by Aho, V. T. E., Heintz-Buschart, A., Landoulsi, Z., Jónsdóttir, S. R., Pauly, C., Pavelka, L., Delacour, L., Kaysen, A., Krüger, R., Wilmes, P., Leist, A. K., Aguayo, Gloria, Alexandre, Myriam, Ali, Muhammad, Ammerlann, Wim, Arena, Giuseppe, Bassis, Michele, Batutu, Roxane, Beaumont, Katy, Béchet, Sibylle, Berchem, Guy, Bisdorff, Alexandre, Bouvier, David, Castillo, Lorieza, De Bremaeker, Nancy, Dewitt, Brian, Diederich, Nico, Ramia, Nancy E, Fritz, Joëlle, Gamio, Carlos, Gawron, Piotr, Georges, Laura, Ghosh, Soumyabrata, Glaab, Enrico, Goergen, Martine, Gómez De Lope, Elisa, Graas, Jérôme, Groues, Valentin, Grünewald, Anne, Hammot, Gaël, Hansen, Linda, Henry, Estelle, Henry, Margaux, Herbrink, Sylvia, Herzinger, Sascha, Hundt, Alexander, Jacoby, Nadine, Jónsdóttir, Sonja, Krüger, Rejko, Lambert, Pauline, Landoulsi, Zied, Longhino, Laura, Marques, Guilherme, Martins Conde, Patricia, May, Patrick, Mcintyre, Deborah, Mediouni, Chouaib, Meisch, Francoise, Mendibide, Alexia, Menster, Myriam, Minelli, Maura, Mittelbronn, Michel, Mtimet, Saïda, Munsch, Maeva, Nehrbass, Ulf, Nickels, Sarah, Nicolai, Beatrice, Nicolay, Jean-Paul, Noor, Fozia, Gomes, Clarissa P. C., Pachchek, Sinthuja, Pavelka, Lukas, Perquin, Magali, Pexaras, Achilleas, Rauschenberger, Armin, Rawal, Rajesh, Reddy Bobbili, Dheeraj, Remark, Lucie, Richard, Ilsé, Roomp, Kirsten, Rosales, Eduardo, Sapienza, Stefano, Satagopam, Venkata, Schmitz, Sabine, Schneider, Reinhard, Schwamborn, Jens, Severino, Raquel, Soare, Ruxandra, Soboleva, Ekaterina, Sokolowska, Kate, Theresine, Maud, Thien, Hermann, Thiry, Elodie, Ting Jiin Loo, Rebecca, Trouet, Johanna, Tsurkalenko, Olena, Vega, Carlos, Vilas Boas, Liliana, Wollscheid-Lengeling, Evi, Zelimkhanov, Gelani

“…Background With differences apparent in the gut microbiome in mild cognitive impairment (MCI) and dementia, and risk factors of dementia linked to alterations…”
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