Search Results - "McIntyre, D C"

Chronic omega-3 supplementation in seizure-prone versus seizure-resistant rat strains: a cautionary tale by Gilby, K.L, Jans, J, McIntyre, D.C

“…Abstract Several studies have shown fatty acid supplementation to be efficacious in the treatment of attention deficit hyperactivity disorder/autism spectrum…”
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Strain differences affect the induction of status epilepticus and seizure-induced morphological changes by Xu, B., McIntyre, D. C., Fahnestock, M., Racine, R. J.

“…Genetic deficits have been discovered in human epilepsy, which lead to alteration of the balance between excitation and inhibition, and ultimately result in…”
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Development of kindling-prone and kindling-resistant rats: selective breeding and electrophysiological studies by Racine, Ronald J, Steingart, Madoka, McIntyre, Dan C

“…Because of the growing need for an animal model of complex partial seizures based on a genetic predisposition, we combined the kindling model of epilepsy with…”
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Zincergic innervation of the forebrain distinguishes epilepsy-prone from epilepsy-resistant rat strains by Flynn, C, Brown, C.E, Galasso, S.L, McIntyre, D.C, Teskey, G. Campbell, Dyck, R.H

“…Abstract Zinc is released from a subset of cerebral cortical neurons whereupon it exerts a powerful modulatory influence on excitatory and inhibitory…”
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Neuro-overprotection? A functional evaluation of clomethiazole-induced neuroprotection following hypoxic-ischemic injury by Gilby, K.L., Kelly, M.E., McIntyre, D.C., Robertson, H.A.

“…Hypoxic-ischemic (H-I) injury produces extensive damage to the hippocampus of young rats. We have recently shown that administration of 125 mg kg −1…”
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FAST and SLOW amygdala kindling rat strains: comparison of amygdala, hippocampal, piriform and perirhinal cortex kindling by McIntyre, Dan C, Kelly, Mary Ellen, Dufresne, Carolynn

“…In our companion paper, we selectively bred offspring of a Long Evans Hooded and Wistar rat cross for either fast or slow rates of amygdala kindling (Racine et…”
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The neurosteroid THDOC differentially affects spatial behavior and anesthesia in Slow and Fast kindling rat strains by Schwabe, K., McIntyre, D.C., Poulter, M.O.

“…Rats selectively bred for “Fast” or “Slow” kindling epileptogenesis express different GABA A receptor subunits that may account for differences in their…”
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Influence of psychogenic and neurogenic stressors on neuroendocrine and central monoamine activity in fast and slow kindling rats by McIntyre, Dan C, Kent, Pam, Hayley, Shawn, Merali, Zul, Anisman, Hymie

“…The central neurochemical and neuroendocrine effects of a psychogenic (ferret exposure) and a neurogenic (restraint) stressor were assessed in rats that had…”
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Cortical spreading depression reversibly disrupts convulsive motor seizure expression in amygdala-kindled rats by Kelly, M.E., Battye, R.A., McIntyre, D.C.

“…To determine the role of the frontal cortex in the generalization of limbic seizures, we first produced unilateral cortical spreading depression to reversibly…”
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Amygdala Kindling-Resistant (SLOW) or -Prone (FAST) Rat Strains Show Differential Fear Responses by Mohapel, Paul, McIntyre, Dan C

“…The authors compared two rat strains, selectively bred for their susceptibility to amygdala kindling, with respect to their performance on various behavioral…”
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Hippocampal kindling protects several structures from the neuronal damage resulting from kainic acid-induced status epilepticus by Kelly, M E, McIntyre, D C

“…In an attempt to study the effects of piriform cortex damage on kindled seizure propagation, we administered kainic acid (12 mg/kg; i.p.) to rats previously…”
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Seizure-induced differential expression of messenger RNAs for neurotrophins and their receptors in genetically fast and slow kindling rats by Kokaia, Z, Kelly, M.E, Elmér, E, Kokaia, M, McIntyre, D.C, Lindvall, O

“…Levels of messenger RNAs for brain-derived neurotrophic factor, nerve growth factor and neurotrophin-3, and their high-affinity receptors, TrkB and TrkC, were…”
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Perirhinal cortex involvement in limbic kindled seizures by Kelly, M.E., McIntyre, D.C.

“…Investigations into the anatomical substrate of temporal lobe epilepsy have yielded a number of important observations regarding the involvement of the…”
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Mossy fibre sprouting: evidence against a facilitatory role in epileptogenesis by Elmér, Eskil, Kokaia, Zaal, Kokaia, Merab, Lindvall, Olle, McIntyre, Dan C

“…SPROUTING of mossy fibres from dentate granule cells occurs in several animal models of epilepsy and in epileptic humans. Mossy fibre sprouting might…”
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Long-lasting changes in the origin of spontaneous discharges from amygdala-kindled rats: piriform vs. perirhinal cortex in vitro by McIntyre, D C, Plant, J R

“…The origin of spontaneous field potentials in coronal slices of the amygdala-piriform-perirhinal area (A-P area) from amygdala-kindled and control rats was…”
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Epileptogenesis induced by rapidly recurring seizures in genetically fast- but not slow-kindling rats by Elmér, Eskil, Kokaia, Merab, Kokaia, Zaal, McIntyre, Dan C, Lindvall, Olle

“…A brief period of rapidly recurring hippocampal seizures can lead to the progressive development of a permanent increase of seizure susceptibility over several…”
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Influence of Psychogenic and Neurogenic Stressors on Endocrine and Immune Activity: Differential Effects in Fast and Slow Seizing Rat Strains by Anisman, H., Lu, Z.W., Song, C., Kent, P., Mcintyre, D.C., Merali, Z.

“…Variations of plasma ACTH and corticosterone, as well as splenic macrophage activity and mitogen-induced cell proliferation, were determined in rats following…”
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Kindling in the perirhinal cortex by McIntyre, D C, Kelly, M E, Armstrong, J N

“…In vitro experiments have indicated that the perirhinal cortex is highly excitable and its relationship to the basolateral amygdala and piriform cortex is…”
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Cellular and synaptic properties of amygdala-kindled pyriform cortex in vitro by McIntyre, D C, Wong, R K

“…The evoked and spontaneous activity of neurons in the pyriform cortex of control and kindled rats was examined using a coronal slice preparation containing the…”
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Distribution of [14C]2-deoxyglucose after various forms and durations of status epilepticus induced by stimulation of a kindled amygdala focus in rats by McIntyre, D C, Don, J C, Edson, N

“…Stimulation of a kindled amygdala focus for 60 min resulted in the development of status epilepticus (SE) in one of 4 forms: ambulatory, masticatory, immobile…”
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