Search Results - "McIntosh, T.J."

Structure, Composition, and Peptide Binding Properties of Detergent Soluble Bilayers and Detergent Resistant Rafts by Gandhavadi, M., Allende, D., Vidal, A., Simon, S.A., McIntosh, T.J.

“…Lipid bilayers composed of unsaturated phosphatidylcholine (PC), sphingomyelin (SM), and cholesterol are thought to contain microdomains that have similar…”
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Repulsive interactions and mechanical stability of polymer-grafted lipid membranes by Needham, D, McIntosh, T J, Lasic, D D

“…Liposome membranes containing lipids with covalently attached poly(ethylene glycol) (PEG-lipid) are currently being developed as drug delivery systems. These,…”
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Probing the ethanol-induced chain interdigitations in gel-state bilayers of mixed-chain phosphatidylcholines by Huang, C., McIntosh, T.J.

“…Using high-resolution differential scanning calorimetry (DSC), we have studied the effects of ethanol concentrations, [EtOH], on the main phase transition…”
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Structure and interactive properties of highly fluorinated phospholipid bilayers by McIntosh, T.J., Simon, S.A., Vierling, P., Santaella, C., Ravily, V.

“…Because liposomes containing fluoroalkylated phospholipids are being developed for in vivo drug delivery, the structure and interactive properties of several…”
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Elasticity, Strength, and Water Permeability of Bilayers that Contain Raft Microdomain-Forming Lipids by Rawicz, W., Smith, B.A., McIntosh, T.J., Simon, S.A., Evans, E.

“…Bilayers composed of phosphatidylcholine (PC), sphingomyelin (SM), and cholesterol (CHOL) are commonly used as systems to model the raft-lipid domain structure…”
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Charge-Reversal Lipids, Peptide-Based Lipids, and Nucleoside-Based Lipids for Gene Delivery by LaManna, Caroline M, Lusic, Hrvoje, Camplo, Michel, McIntosh, Thomas J, Barthélémy, Philippe, Grinstaff, Mark W

“…Twenty years after gene therapy was introduced in the clinic, advances in the technique continue to garner headlines as successes pique the interest of…”
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Interdigitated hydrocarbon chain packing causes the biphasic transition behavior in lipid/alcohol suspensions by Simon, S A, McIntosh, T J

“…It has been shown recently by Rowe ((1983) Biochemistry 22, 3299-3305) that ethanol has a 'biphasic' effect on the transition temperature (Tm) of…”
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Increased adhesion between neutral lipid bilayers: interbilayer bridges formed by tannic acid by Simon, S.A., Disalvo, E.A., Gawrisch, K., Borovyagin, V., Toone, E., Schiffman, S.S., Needham, D., McIntosh, T.J.

“…Tannic acid (TA) is a naturally occurring polyphenolic compound that aggregates membranes and neutral phosolipid vesicles and precipitates many proteins. This…”
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Differences in hydrocarbon chain tilt between hydrated phosphatidylethanolamine and phosphatidylcholine bilayers. A molecular packing model by McIntosh, T.J.

“…Both wide-angle and lamellar x-ray diffraction data are interpreted in terms of a difference in hydrocarbon chain tilt between fully hydrated dipalmitoyl…”
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Synthesis, structure, and thermal properties of 1,2-dipalmitoylgalloylglycerol (DPGG), a novel self-adhering lipid by Pollastri, M.P., Porter, N.A., McIntosh, T.J., Simon, S.A.

“…A novel diacyl glycerol-based lipid with a polyphenolic head group has been synthesized and characterized. X-ray diffraction experiments show that this lipid,…”
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Charge-Reversal Amphiphiles for Gene Delivery by Prata, Carla A. H, Zhao, Yuxing, Barthelemy, Philippe, Li, Yougen, Luo, Dan, McIntosh, Thomas J, Lee, Stephen J, Grinstaff, Mark W

“…Delivering a missing gene or a functional substitute of a defective gene has the potential to revolutionize current medical care. Of the two gene delivery…”
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Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly(ethylene glycol) by Kenworthy, A.K., Hristova, K., Needham, D., McIntosh, T.J.

“…The interactive properties of liposomes containing phospholipids with covalently attached poly(ethylene glycol) (PEG-lipids) are of interest because such…”
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Structure and phase behavior of lipid suspensions containing phospholipids with covalently attached poly(ethylene glycol) by Kenworthy, A.K., Simon, S.A., McIntosh, T.J.

“…Liposomes containing phospholipids with covalently attached poly(ethylene glycol) (PEG-lipids) are being developed for in vivo drug delivery. In this paper we…”
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Gelation of liposome interior A novel method for drug encapsulation by Lasic, D.D., Frederik, P.M., Stuart, M.C.A., Barenholz, Y., McIntosh, T.J.

“…Liposomes can be loaded with weak acids and bases, which exist in solutions in equilibrium with membrane permeable uncharged form, using various gradients…”
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Temperature dependence of the repulsive pressure between phosphatidylcholine bilayers by Simon, S.A., Advani, S., McIntosh, T.J.

“…Bilayer structure and interbilayer repulsive pressure were measured from 5 to 50 degrees C by the osmotic stress/x-ray diffraction method for both gel and…”
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The interaction of polyphenols with bilayers: conditions for increasing bilayer adhesion by Huh, N.W., Porter, N.A., McIntosh, T.J., Simon, S.A.

“…Because proteins and other molecules with a high polyphenol content are commonly involved in adhesion processes, we are investigating the interactions between…”
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Cholesterol modifies the short-range repulsive interactions between phosphatidylcholine membranes by McIntosh, Thomas J, Magid, Alan D, Simon, Sidney A

“…Pressure versus distance relationships have been obtained for egg phosphatidylcholine bilayers containing a range of cholesterol concentrations. Water was…”
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Modulation of the interbilayer hydration pressure by the addition of dipoles at the hydrocarbon/water interface by Simon, S.A., McIntosh, T.J., Magid, A.D., Needham, D.

“…The effects of the cholesterol analog 5 alpha-cholestan-3 beta-ol-6-one (6-ketocholestanol) on bilayer structure, bilayer cohesive properties, and interbilayer…”
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Determination of the depth of bromine atoms in bilayers formed from bromolipid probes by McIntosh, T. O, Holloway, Peter W

“…X-ray diffraction analysis has been performed on a series of 1-palmitoyl-2-dibromostearoyl-phosphatidylcholines (BRPCs) with bromine atoms at the 6, 7-, the…”
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Repulsive interactions between uncharged bilayers. Hydration and fluctuation pressures for monoglycerides by McIntosh, T.J., Magid, A.D., Simon, S.A.

“…Pressure versus distance relations have been obtained for solid (gel) and neat (liquid-crystalline) phase uncharged lipid bilayers by the use of x-ray…”
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