Search Results - "McIntosh, M A"

A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence by Hill, W. D., Marioni, R. E., Maghzian, O., Ritchie, S. J., Hagenaars, S. P., McIntosh, A. M., Gale, C. R., Davies, G., Deary, I. J.

“…Intelligence, or general cognitive function, is phenotypically and genetically correlated with many traits, including a wide range of physical, and mental…”
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Working memory in schizophrenia: a meta-analysis by Forbes, N F, Carrick, L A, McIntosh, A M, Lawrie, S M

“…Memory impairment is being recognized increasingly as an important feature of the neuropsychology of schizophrenia. Dysfunction of working memory, a system for…”
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Magnetic resonance imaging studies in bipolar disorder and schizophrenia: meta-analysis by Arnone, D., Cavanagh, J., Gerber, D., Lawrie, S. M., Ebmeier, K. P., McIntosh, A. M.

“…Several magnetic resonance imaging (MRI) studies have identified structural abnormalities in association with bipolar disorder. The literature is, however,…”
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Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151) by Davies, G, Marioni, R E, Liewald, D C, Hill, W D, Hagenaars, S P, Harris, S E, Ritchie, S J, Luciano, M, Fawns-Ritchie, C, Lyall, D, Cullen, B, Cox, S R, Hayward, C, Porteous, D J, Evans, J, McIntosh, A M, Gallacher, J, Craddock, N, Pell, J P, Smith, D J, Gale, C R, Deary, I J

“…People’s differences in cognitive functions are partly heritable and are associated with important life outcomes. Previous genome-wide association (GWA)…”
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Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci by Smith, D J, Escott-Price, V, Davies, G, Bailey, M E S, Colodro-Conde, L, Ward, J, Vedernikov, A, Marioni, R, Cullen, B, Lyall, D, Hagenaars, S P, Liewald, D C M, Luciano, M, Gale, C R, Ritchie, S J, Hayward, C, Nicholl, B, Bulik-Sullivan, B, Adams, M, Couvy-Duchesne, B, Graham, N, Mackay, D, Evans, J, Smith, B H, Porteous, D J, Medland, S E, Martin, N G, Holmans, P, McIntosh, A M, Pell, J P, Deary, I J, O'Donovan, M C

“…Neuroticism is a personality trait of fundamental importance for psychological well-being and public health. It is strongly associated with major depressive…”
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Genetic contributions to self-reported tiredness by Deary, V, Hagenaars, S P, Harris, S E, Hill, W D, Davies, G, Liewald, D C M, McIntosh, A M, Gale, C R, Deary, I J

“…Self-reported tiredness and low energy, often called fatigue, are associated with poorer physical and mental health. Twin studies have indicated that this has…”
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Structural magnetic resonance imaging markers of susceptibility and transition to schizophrenia: A review of familial and clinical high risk population studies by Bois, C, Whalley, HC, McIntosh, AM, Lawrie, SM

“…There is a growing consensus that a symptomatology as complex and heterogeneous as schizophrenia is likely to be produced by widespread perturbations of brain…”
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The effects of a neuregulin 1 variant on white matter density and integrity by McIntosh, A M, Moorhead, T W J, Job, D, Lymer, G K S, Muñoz Maniega, S, McKirdy, J, Sussmann, J E D, Baig, B J, Bastin, M E, Porteous, D, Evans, K L, Johnstone, E C, Lawrie, S M, Hall, J

“…Theories of abnormal anatomical and functional connectivity in schizophrenia and bipolar disorder are supported by evidence from functional magnetic resonance…”
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Seizure Outcome after Temporal Lobectomy: Current Research Practice and Findings by McIntosh, A. M., Wilson, S. J., Berkovic, S. F.

“…Purpose: The literature regarding seizure outcome and prognostic factors for outcome after temporal lobectomy is often contradictory. This is problematic, as…”
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Genetic contributions to Trail Making Test performance in UK Biobank by Hagenaars, S P, Cox, S R, Hill, W D, Davies, G, Liewald, D C M, Harris, S E, McIntosh, A M, Gale, C R, Deary, I J

“…The Trail Making Test (TMT) is a widely used test of executive function and has been thought to be strongly associated with general cognitive function. We…”
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Polygenic risk for schizophrenia, transition and cortical gyrification: a high-risk study by Neilson, E, Bois, C, Clarke, T-K, Hall, L, Johnstone, E C, Owens, D G C, Whalley, H C, McIntosh, A M, Lawrie, S M

“…Schizophrenia is a highly heritable disorder, linked to several structural abnormalities of the brain. More specifically, previous findings have suggested that…”
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The role of neuroticism in self-harm and suicidal ideation: results from two UK population-based cohorts by Hafferty, Jonathan D., Navrady, L. B., Adams, M. J., Howard, D. M., Campbell, A. I., Whalley, H. C., Lawrie, S. M., Nicodemus, K. K., Porteous, D. J., Deary, I. J., McIntosh, A. M.

“…Background Self-harm is common, debilitating and associated with completed suicide and increased all-cause mortality, but there is uncertainty about its causal…”
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Meta-analysis of magnetic resonance imaging studies of the corpus callosum in schizophrenia by Arnone, D, McIntosh, A.M, Tan, G.M.Y, Ebmeier, K.P

“…Abstract Objectives The corpus callosum plays a pivotal role in inter-hemispheric transfer and integration of information. Magnetic resonance studies have…”
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Meta-analysis of magnetic resonance imaging studies of the corpus callosum in bipolar disorder by Arnone, D., McIntosh, A. M., Chandra, P., Ebmeier, K. P.

“…Objective:  The corpus callosum (CC) plays a pivotal role in inter‐hemispheric transfer and integration of information and is a relatively understudied…”
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DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan by Porteous, D J, Thomson, P A, Millar, J K, Evans, K L, Hennah, W, Soares, D C, McCarthy, S, McCombie, W R, Clapcote, S J, Korth, C, Brandon, N J, Sawa, A, Kamiya, A, Roder, J C, Lawrie, S M, McIntosh, A M, St Clair, D, Blackwood, D H

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708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits by Thomson, P A, Parla, J S, McRae, A F, Kramer, M, Ramakrishnan, K, Yao, J, Soares, D C, McCarthy, S, Morris, S W, Cardone, L, Cass, S, Ghiban, E, Hennah, W, Evans, K L, Rebolini, D, Millar, J K, Harris, S E, Starr, J M, MacIntyre, D J, McIntosh, A M, Watson, J D, Deary, I J, Visscher, P M, Blackwood, D H, McCombie, W R, Porteous, D J

“…A balanced t(1;11) translocation that transects the Disrupted in schizophrenia 1 (DISC1) gene shows genome-wide significant linkage for schizophrenia and…”
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Neuroticism, depressive symptoms and white-matter integrity in the Lothian Birth Cohort 1936 by McIntosh, A M, Bastin, M E, Luciano, M, Maniega, S Muñoz, Del C Valdés Hernández, M, Royle, N A, Hall, J, Murray, C, Lawrie, S M, Starr, J M, Wardlaw, J M, Deary, I J

“…Clinical depression is associated with reductions in white-matter integrity in several long tracts of the brain. The extent to which these findings are…”
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Prefrontal gyral folding and its cognitive correlates in bipolar disorder and schizophrenia by McIntosh, A. M., Moorhead, T. W. J., McKirdy, J., Hall, J., Sussmann, J. E. D., Stanfield, A. C., Harris, J. M., Johnstone, E. C., Lawrie, S. M.

“…Objective:  We sought to address whether dorsal or ventral prefrontal gyrification is abnormal in bipolar disorder and to determine its diagnostic specificity…”
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Temporal lobectomy: long-term seizure outcome, late recurrence and risks for seizure recurrence by McIntosh, Anne M., Kalnins, Renate M., Mitchell, L. Anne, Fabinyi, Gavin C. A., Briellmann, Regula S., Berkovic, Samuel F.

“…There is little information available relevant to long-term seizure outcome after anterior temporal lobectomy, particularly at extended postoperative periods…”
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Hippocampal function in schizophrenia and bipolar disorder by Hall, J, Whalley, H C, Marwick, K, McKirdy, J, Sussmann, J, Romaniuk, L, Johnstone, E C, Wan, H I, McIntosh, A M, Lawrie, S M

“…The hippocampus plays a central role in memory formation. There is considerable evidence of abnormalities in hippocampal structure and function in…”
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