Search Results - "McInnes, P."
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Novel Gd-Loaded Silicon Nanohybrid: A Potential Epidermal Growth Factor Receptor Expressing Cancer Cell Targeting Magnetic Resonance Imaging Contrast Agent
Published in ACS applied materials & interfaces (13-12-2017)“…Continuing our research efforts in developing mesoporous silicon nanoparticle-based biomaterials for cancer therapy, we employed here porous silicon…”
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2
Moose browsing and soil fertility in the boreal forests of Isle Royale National Park
Published in Ecology (Durham) (01-03-1993)“…Selective foraging by moose on hardwoods and avoidance of conifers alters community composition and structure, which in turn can affect nutrient cycles and…”
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Electrospun Composites of Polycaprolactone and Porous Silicon Nanoparticles for the Tunable Delivery of Small Therapeutic Molecules
Published in Nanomaterials (Basel, Switzerland) (29-03-2018)“…This report describes the use of an electrospun composite of poly(ε-caprolactone) (PCL) fibers and porous silicon (pSi) nanoparticles (NPs) as an effective…”
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Fabrication and Characterization of a Porous Silicon Drug Delivery System with an Initiated Chemical Vapor Deposition Temperature-Responsive Coating
Published in Langmuir (12-01-2016)“…This paper reports on the fabrication of a pSi-based drug delivery system, functionalized with an initiated chemical vapor deposition (iCVD) polymer film, for…”
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Stimulus-Responsiveness and Drug Release from Porous Silicon Films ATRP-Grafted with Poly(N-isopropylacrylamide)
Published in Langmuir (21-06-2011)“…In this report, we employ surface-initiated atom transfer radical polymerization (SI-ATRP) to graft a thermoresponsive polymer, poly(N-isopropylacrylamide)…”
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Combination of iCVD and Porous Silicon for the Development of a Controlled Drug Delivery System
Published in ACS applied materials & interfaces (25-07-2012)“…We describe a pH responsive drug delivery system which was fabricated using a novel approach to functionalize biodegradeable porous silicon (pSi) by initiated…”
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Effects of moose browsing on vegetation and litter of the boreal forest, Isle Royale, Michigan, USA
Published in Ecology (Durham) (01-12-1992)“…Large mammalian herbivores can influence the dynamics and structure of ecosystems by selectively removing tissues of specific plant species. The plant…”
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“Thunderstruck”: Plasma-Polymer-Coated Porous Silicon Microparticles As a Controlled Drug Delivery System
Published in ACS applied materials & interfaces (24-02-2016)“…Controlling the release kinetics from a drug carrier is crucial to maintain a drug’s therapeutic window. We report the use of biodegradable porous silicon…”
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Delivery of Flightless I Neutralizing Antibody from Porous Silicon Nanoparticles Improves Wound Healing in Diabetic Mice
Published in Advanced healthcare materials (01-01-2017)“…Flightless I (Flii) is elevated in human chronic wounds and is a negative regulator of wound repair. Decreasing its activity improves healing responses. Flii…”
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Controlled drug delivery from composites of nanostructured porous silicon and poly(L-lactide)
Published in Nanomedicine (London, England) (01-07-2012)“…Porous silicon (pSi) and poly(L-lactide) (PLLA) both display good biocompatibility and tunable degradation behavior, suggesting that composites of both…”
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Nanomaterial and advanced technologies in transdermal drug delivery
Published in Journal of drug targeting (20-04-2020)“…Transdermal drug delivery (TDD) is an alternative method of drug administration for drugs whose delivery by conventional oral, topical, intravenous and…”
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Porous silicon for drug delivery applications and theranostics: recent advances, critical review and perspectives
Published in Expert opinion on drug delivery (02-12-2017)“…Porous silicon (pSi) engineered by electrochemical etching has been used as a drug delivery vehicle to address the intrinsic limitations of traditional…”
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Augmented physical, mechanical, and cellular responsiveness of gelatin-aldehyde modified xanthan hydrogel through incorporation of silicon nanoparticles for bone tissue engineering
Published in International journal of biological macromolecules (01-02-2024)“…Bioactive scaffolds fabricated from a combination of organic and inorganic biomaterials are a promising approach for addressing defects in bone tissue…”
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14
Polymerization-Amplified Optical DNA Detection on Porous Silicon Templates
Published in ACS macro letters (17-07-2012)“…A porous silicon-based optical DNA sensor is described herein, which enables rapid DNA detection. The DNA sensor relies on the specificity of the DNA base…”
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15
Lateral heterogeneities in supported bilayers from pure and mixed phosphatidylethanolamine demonstrating hydrogen bonding capacity
Published in Biointerphases (01-12-2008)“…The phase behavior and lateral organization of saturated phosphatidylethanolamine (PE) and phosphatidylcholine (PC) bilayers were investigated using atomic…”
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Dissolving microneedle-assisted long-acting Liraglutide delivery to control type 2 diabetes and obesity
Published in European journal of pharmaceutical sciences (01-12-2021)“…Integrating nanoparticles (NPs) as a smart and targeted tool for drug delivery with dissolving microneedle (DMN) patch, the non-invasive device for drug…”
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Wound Healing: Delivery of Flightless I Neutralizing Antibody from Porous Silicon Nanoparticles Improves Wound Healing in Diabetic Mice (Adv. Healthcare Mater. 2/2017)
Published in Advanced healthcare materials (01-01-2017)“…The delivery of Flightless neutralizing antibody‐loaded porous silicon nanoparticles to diabetic mice wounds significantly improves healing, with porous…”
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Characteristics of SARS-CoV2 that may be useful for nanoparticle pulmonary drug delivery
Published in Journal of drug targeting (16-03-2022)“…As a non-invasive method of local and systemic drug delivery, the administration of active pharmaceutical ingredients (APIs) via the pulmonary route represents…”
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Murine and Non-Human Primate Dendritic Cell Targeting Nanoparticles for in Vivo Generation of Regulatory T‑Cells
Published in ACS nano (24-07-2018)“…Porous silicon nanoparticles (pSiNP), modified to target dendritic cells (DC), provide an alternate strategy for the delivery of immunosuppressive drugs. Here,…”
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Subcutaneous maternal resveratrol treatment increases uterine artery blood flow in the pregnant ewe and increases fetal but not cardiac growth
Published in The Journal of physiology (01-10-2019)“…Key points Substrate restriction during critical developmental windows of gestation programmes offspring for a predisposition towards cardiovascular disease in…”
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