Search Results - "McIlroy, S P"

A retrospective study of the behavioural and psychological symptoms of mid and late phase Alzheimer's disease by Hart, D. J., Craig, D., Compton, S. A., Critchlow, S., Kerrigan, B. M., McIlroy, S. P., Passmore, A. P.

“…Aim To document the behavioural and psychological symptoms in patients with a diagnosis of established Alzheimer's disease (AD) for at least 3 years. Methods…”
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Behavioural and psychological syndromes in Alzheimer's disease by Mirakhur, A., Craig, D., Hart, D. J., Mcllroy, S. P., Passmore, A. P.

“…Objectives The origins of behavioural and psychological symptoms of dementia are still poorly understood. By focusing on piecemeal behaviours as opposed to…”
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Apolipoprotein E e4 allele influences aggressive behaviour in Alzheimer’s disease by Craig, D, Hart, D J, McCool, K, McIlroy, S P, Passmore, A P

“…The rising number of people with cognitive impairment is placing health care budgets under significant strain. Dementia related behavioural change is a major…”
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Butyrylcholinesterase K variant is genetically associated with late onset Alzheimer's disease in Northern Ireland by McIlroy, S P, Crawford, V L S, Dynan, K B, McGleenon, B M, Vahidassr, M D, Lawson, J T, Passmore, A P

“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder that has been associated, sometimes controversially, with polymorphisms in a number of…”
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Risk of Alzheimer's disease is associated with a very low-density lipoprotein receptor genotype in northern Ireland by McIlroy, Stephen P., Vahidassr, M. Djamil, Savage, David A., Patterson, Christopher C., Lawson, John T., Passmore, A. Peter

“…The ϵ‐4 allele of apolipoprotein E (APOE) is associated with increased risk of Alzheimer's disease (AD), but the pathogenic mechanism is unknown. The 5‐repeat…”
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Association of serum AACT levels and AACT signal polymorphism with late-onset Alzheimer's disease in Northern Ireland by McIlroy, S. P., Vahidassr, M. D., Savage, D. A., Lloyd, F., Patterson, C. C., Lawson, J. T., Passmore, A. P.

“…α1‐antichymotrypsin (AACT) is a serine protease inhibitor that has been associated with amyloid plaques in the brains of patients with Alzheimer's disease…”
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Association between polymorphism in regulatory region of gene encoding tumour necrosis factor α and risk of Alzheimer's disease and vascular dementia: a case-control study by McCusker, Shauna M, Curran, Martin D, Dynan, Kevin B, McCullagh, Catriona D, Urquhart, Duncan D, Middleton, Derek, Patterson, Christopher C, McIlroy, Stephen P, Peter Passmore, A

“…Deposition of β-amyloid in the brains of patients with Alzheimer's disease is thought to precede a chain of events that leads to an inflammatory response by…”
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Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland by MCILROY, Stephen P, DYNAN, Kevin B, LAWSON, John T, PATTERSON, Christopher C, PASSMORE, A. Peter

“…Elevated plasma homocysteine level has been associated with increased risk for cardiovascular and cerebrovascular disease. Variation in the levels of this…”
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Allelic variation at the A218C tryptophan hydroxylase polymorphism influences agitation and aggression in Alzheimer's disease by Craig, David, Hart, Dominic J., Carson, Robin, McIlroy, Stephen P., Passmore, A.Peter

“…The behavioural and psychological symptoms of dementia are common, distressing to carers, and directly linked to the requirement for institutional care…”
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Common polymorphisms in LRP and A2M do not affect genetic risk for Alzheimer disease in Northern Ireland by McIlroy, Stephen P., Dynan, Kevin B., Vahidassr, D Jamil, Lawson, John T., Patterson, Christopher C., Passmore, Peter

“…Genetic variation in one of the major APOE receptors in the brain has been associated with increased risk for Alzheimer disease (AD). A C/T polymorphism in…”
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A cross-sectional study of neuropsychiatric symptoms in 435 patients with Alzheimer's disease by Craig, David, Mirakhur, Ajay, Hart, Dominic J, McIlroy, Stephen P, Passmore, A Peter

“…The behavioral and psychological symptoms of Alzheimer's disease (AD) are associated with significant patient and caregiver distress and increased likelihood…”
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Two-Photon Photosensitized Production of Singlet Oxygen in Water by Frederiksen, Peter K, McIlroy, Sean P, Nielsen, Christian B, Nikolajsen, Lars, Skovsen, Esben, Jørgensen, Mikkel, Mikkelsen, Kurt V, Ogilby, Peter R

“…Singlet molecular oxygen (a1Δg) has been produced and optically detected in time-resolved experiments upon nonlinear two-photon excitation of a photosensitizer…”
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Two-Photon Photosensitized Production of Singlet Oxygen:  Sensitizers with Phenylene−Ethynylene-Based Chromophores by McIlroy, Sean P, Cló, Emiliano, Nikolajsen, Lars, Frederiksen, Peter K, Nielsen, Christian B, Mikkelsen, Kurt V, Gothelf, Kurt V, Ogilby, Peter R

“…Singlet molecular oxygen (a1Δg) has been produced and optically monitored in time-resolved experiments upon nonlinear two-photon excitation of photosensitizers…”
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Synthesis and Characterization of Water-Soluble Phenylene−Vinylene-Based Singlet Oxygen Sensitizers for Two-Photon Excitation by Nielsen, Christian B, Johnsen, Mette, Arnbjerg, Jacob, Pittelkow, Michael, McIlroy, Sean P, Ogilby, Peter R, Jørgensen, Mikkel

“…The synthesis and characterization of water-soluble singlet oxygen sensitizers with a phenylene−vinylene motif is presented. The principal motivation for this…”
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Singlet Oxygen Microscope:  From Phase-Separated Polymers to Single Biological Cells by Snyder, John W, Zebger, Ingo, Gao, Zhan, Poulsen, Lars, Frederiksen, Peter K, Skovsen, Esben, McIlroy, Sean P, Klinger, Markus, Andersen, Lars Klembt, Ogilby, Peter R

“…The lowest excited electronic state of molecular oxygen, singlet molecular oxygen (aΔg), is an intermediate in many chemical and biological processes. Tools…”
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Cathepsin D gene exon 2 polymorphism and sporadic Alzheimer's disease by McIlroy, Stephen P, Dynan, Kevin B, McGleenon, Bronagh M, Lawson, John T, Passmore, A.Peter

“…It has recently been reported that a genetic polymorphism in exon 2 of the cathepsin D gene conferred increased risk for development of Alzheimer's disease…”
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The interleukin 1β gene promoter polymorphism (−511) acts as a risk factor for psychosis in Alzheimer's dementia by Craig, David, Hart, Dominic J., McCool, Keira, McIlroy, Stephen P., Passmore, A. Peter

“…The explanation for why some patients develop psychotic change in Alzheimer's disease (AD) is unclear. “Psychosis‐modifier genes” may act in the setting of…”
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Psychotic symptoms in Alzheimer’s disease are not influenced by polymorphic variation at the dopamine receptor DRD3 gene by Craig, David, Hart, Dominic J., Carson, Robyn, McIlroy, Stephen P., Passmore, A. Peter

“…It has been suggested that genetic influences unmasked during neurodevelopment to produce schizophrenia may appear throughout neurodegeneration to produce AD…”
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Diphenylnitrenium Ion:  Cyclization, Electron Transfer, and Polymerization Reactions by Kung, Andrew C, McIlroy, Sean P, Falvey, Daniel E

“…Reactions of diphenylnitrenium ion were examined using laser flash photolysis (LFP), product analysis, and computational modeling using density functional…”
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Association between polymorphism in regulatory region of gene encoding tumour necrosis factor alpha and risk of Alzheimer's disease and vascular dementia: a case-control study by McCusker, S M, Curran, MD, Dynan, K B, McCullagh, C D, Urquhart, D D, Middleton, D, Patterson, C C, McIlroy, S P, Passmore, AP

“…Deposition of beta -amyloid in the brains of patients with Alzheimer's disease is thought to precede a chain of events that leads to an inflammatory response…”
Get full text