Search Results - "McIldowie, Matthew"

Synthesis of Distally‐Bridged Chiral Resorcinarene Crowns by Tan, Daniel A., Massera, Chiara, McIldowie, Matthew J., Mocerino, Mauro

“…Our interest in the potential of chiral tetramethoxy‐resorcinarene as agents for chiral recognition has led us to synthesise twelve distally‐bridged chiral…”
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Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease by Johnston, Tom H, Fox, Susan H, McIldowie, Matthew J, Piggott, Matthew J, Brotchie, Jonathan M

“…Long-term motor complications of dopamine replacement, such as L-DOPA-induced dyskinesia (LID) and reduced quality of L-DOPA action, remain obstacles in the…”
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Structural Variations in the Complete Series of Lanthanoid Complexes of a Calix[4]arene Trisamide by Nealon, Gareth L, McIldowie, Matthew J, Skelton, Brian W, Mocerino, Mauro, Massi, Massimiliano, Ogden, Mark I

“…Lanthanoid picrate (pic) complexes of 5,11,17,23-tetra-tert-butyl-25-hydroxy-26,27,28-tris(diethylcarbamoylmethoxy)calix[4]arene (LH) have been synthesised and…”
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Confirmation of the Revised Structure of Samoquasine A and a Proposed Structural Revision of Cherimoline by Dhoro, Francis, Parkin-Gibbs, Jesse, McIldowie, Matthew, Skelton, Brian W, Piggott, Matthew J

“…The identity of the natural product samoquasine A has remained obscure since its isolation from custard apple seeds in 2000. One of the proposed structures,…”
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Characterization and Inhibition of a Nickel-Alpha-Hydroxyoxime (LIX 63) Salt Precipitate Formed under Proposed Commercial Operating Conditions by Barnard, Keith R, Shiers, Denis W, McIldowie, Matthew J, Skelton, Brian W, Ogden, Mark I, McCoy, Tannice M

“…As a prospective commercial solvent extraction (SX) process, laboratory-scale continuous tests were recently undertaken to assess the use of a solution of LIX…”
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Use of pifithrin to inhibit p53-mediated signalling of TNF in dystrophic muscles of mdx mice by Waters, Felicity J, Shavlakadze, Thea, McIldowie, Matthew J, Piggott, Matthew J, Grounds, Miranda D

“…Tumour Necrosis Factor (TNF) plays a major role in exacerbating necrosis of dystrophic muscle; however, the precise molecular mechanism underlying this effect…”
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Facile Lewis Acid Catalyzed Synthesis of C 4 Symmetric Resorcinarenes by McIldowie, Matthew J, Mocerino, Mauro, Skelton, Brian W, White, Allan H

“…The Lewis acid catalyzed condensation of 3-methoxyphenol with octanal produced the C 4 symmetric calix[4]resorcinarene 2, in high yield. Of the numerous…”
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Identification of a novel C33 n-alkylcyclohexane biomarker in Permian-Triassic sediments by MCILDOWIE, Matthew, ALEXANDER, Robert

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Insights into the mechanism and regulation of pyruvate carboxylase by characterisation of a biotin-deficient mutant of the Bacillus thermodenitrificans enzyme by Adina-Zada, Abdussalam, Jitrapakdee, Sarawut, Surinya, Kathy H., McIldowie, Matthew J., Piggott, Matthew J., Cleland, W. Wallace, Wallace, John C., Attwood, Paul V.

“…Pyruvate carboxylase is a biotin-dependent enzyme in which the biotin is carboxylated by a putative carboxyphosphate intermediate that is formed in a reaction…”
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Analysis of trimethyl carboxyphosphate by gas chromatography–mass spectrometry by McIldowie, Matthew J., Attwood, Paul V., Reeder, Anthony, Piggott, Matthew J.

“…Analysis of trimethyl carboxyphosphate samples by gas chromatography–mass spectrometry, using typical conditions resulted in significant decomposition of the…”
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Physical and crystallographic characterisation of the mGlu5 antagonist MTEP and its monohydrochloride by McIldowie, Matthew J, Gandy, Michael N, Skelton, Brian W, Brotchie, Jonathan M, Koutsantonis, George A, Spackman, Mark A, Piggott, Matthew J

“…An improved medium scale synthesis of 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP), a selective and potent metabotropic glutamate subtype 5 (mGlu5)…”
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Mannich and O-Alkylation Reactions of Tetraalkoxyresorcin[4]arenes - The Use of Some Products in Ligand-Assisted Reactions by Buckley, Benjamin R., Boxhall, Jonathan Y., Page, Philip C. Bulman, Chan, Yohan, Elsegood, Mark R. J., Heaney, Harry, Holmes, Kathryn E., McIldowie, Matthew J., McKee, Vickie, McGrath, Matthew J., Mocerino, Mauro, Poulton, Andrew M., Sampler, Edward P., Skelton, Brian W., White, Allan H.

“…The measurement of the pKa of racemic tetramethoxyresorcin[4]arenes explains the failure to obtain good yields in attempted Mannich reactions of these…”
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A lanthanum picrate complex of a 1,2-bisamide substituted calix[4]arene by McIldowie, Matthew J., Skelton, Brian W., Mocerino, Mauro, Ogden, Mark I.

“…The synthesis and structural characterization of a lanthanum picrate complex of the proximally-substituted calix[4]arene bisamide,…”
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C 4 Dissymmetric resorcinarene derivatives: synthesis, crystal structure and micelle formation by McIldowie, Matthew J., Mocerino, Mauro, Ogden, Mark I., Skelton, Brian W., White, Allan H.

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C4 Dissymmetric resorcinarene derivatives: synthesis, crystal structure and micelle formation by McIldowie, Matthew J., Mocerino, Mauro, Ogden, Mark I., Skelton, Brian W., White, Allan H.

“…The synthesis of a C 4 dissymmetric resorcinarene tetracarboxylic acid derivative and determination of its critical micelle concentration is reported. The…”
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Identification of a novel C sub(33) n-alkylcyclohexane biomarker in Permian-Triassic sediments by McIldowie, Matthew, Alexander, Robert

“…A C sub(33) n-alkylcyclohexane (n-heptacosylcyclohexane) has been used as a biomarker for oil correlation studies in the Perth Basin (Basal Triassic, Western…”
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Pyridine-functionalised C4 symmetric resorcinarenes by McIldowie, Matthew J., Mocerino, Mauro, Ogden, Mark I., Skelton, Brian W.

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Pyridine-functionalised C 4 symmetric resorcinarenes by McIldowie, Matthew J., Mocerino, Mauro, Ogden, Mark I., Skelton, Brian W.

“…Racemic mixtures of C 4 symmetric resorcinarenes have been functionalised by adding 2- and 3-picolyl ether functional groups. Three of the resulting…”
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A novel MDMA analogue, UWA‐101, that lacks psychoactivity and cytotoxicity, enhances l‐DOPA benefit in parkinsonian primates by Johnston, Tom H., Millar, Zak, Huot, Philippe, Wagg, Keith, Thiele, Sherri, Salomonczyk, Danielle, Yong‐Kee, Christopher J., Gandy, Michael N., McIldowie, Matthew, Lewis, Katie D., Gomez‐Ramirez, Jordi, Lee, Joohyung, Fox, Susan H., Martin‐Iverson, Mathew, Nash, Joanne E., Piggott, Matthew J., Brotchie, Jonathan M.

“…Treatment of Parkinson's disease with dopaminergic agents, such as l‐DOPA, is frequently compromised by disabling side effects, particularly dyskinesia and a…”
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Enhancing the anti-lymphoma potential of 3,4-methylenedioxymethamphetamine (‘ecstasy’) through iterative chemical redesign: mechanisms and pathways to cell death by Wasik, Agata M., Gandy, Michael N., McIldowie, Matthew, Holder, Michelle J., Chamba, Anita, Challa, Anita, Lewis, Katie D., Young, Stephen P., Scheel-Toellner, Dagmar, Dyer, Martin J., Barnes, Nicholas M., Piggott, Matthew J., Gordon, John

“…Summary While 3,4-methylenedioxymethamphetamine (MDMA/‘ecstasy’) is cytostatic towards lymphoma cells in vitro, the concentrations required militate against…”
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