Search Results - "McHugh, Tyne L. M."

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    Small molecule modulation of TrkB and TrkC neurotrophin receptors prevents cholinergic neuron atrophy in an Alzheimer's disease mouse model at an advanced pathological stage by Gonzalez, Selena, McHugh, Tyne L.M., Yang, Tao, Syriani, Wassim, Massa, Stephen M., Longo, Frank M., Simmons, Danielle A.

    Published in Neurobiology of disease (01-01-2022)
    “…Degeneration of basal forebrain cholinergic neurons (BFCNs) in the nucleus basalis of Meynert (NBM) and vertical diagonal band (VDB) along with their…”
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    Neuroimaging, Urinary, and Plasma Biomarkers of Treatment Response in Huntington's Disease: Preclinical Evidence with the p75 NTR Ligand LM11A-31 by Simmons, Danielle A, Mills, Brian D, Butler Iii, Robert R, Kuan, Jason, McHugh, Tyne L M, Akers, Carolyn, Zhou, James, Syriani, Wassim, Grouban, Maged, Zeineh, Michael, Longo, Frank M

    Published in Neurotherapeutics (01-04-2021)
    “…Huntington's disease (HD) is caused by an expansion of the CAG repeat in the huntingtin gene leading to preferential neurodegeneration of the striatum…”
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    Journal Article