Search Results - "McHugh, P.E."

The role of elastic anisotropy, length scale and crystallographic slip in fatigue crack nucleation by Sweeney, C.A., Vorster, W., Leen, S.B., Sakurada, E., McHugh, P.E., Dunne, F.P.E.

“…Fatigue crack nucleation in polycrystal ferritic steel is investigated through experimental observation of multiple large-grained, notched, four-point bend…”
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A physical corrosion model for bioabsorbable metal stents by Grogan, J.A., Leen, S.B., McHugh, P.E.

“…Absorbable metal stents (AMSs) are an emerging technology in the treatment of heart disease. Computational modelling of AMS performance will facilitate the…”
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A corrosion model for bioabsorbable metallic stents by Grogan, J.A., O’Brien, B.J., Leen, S.B., McHugh, P.E.

“…In this study a numerical model is developed to predict the effects of corrosion on the mechanical integrity of bioabsorbable metallic stents. To calibrate the…”
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Comparing coronary stent material performance on a common geometric platform through simulated bench testing by Grogan, J.A., Leen, S.B., McHugh, P.E.

“…Absorbable metallic stents (AMSs) are a newly emerging cardiovascular technology which has the potential to eliminate long-term patient health risks associated…”
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A prediction of cell differentiation and proliferation within a collagen–glycosaminoglycan scaffold subjected to mechanical strain and perfusive fluid flow by Stops, A.J.F, Heraty, K.B, Browne, M, O'Brien, F.J, McHugh, P.E

“…Abstract Mesenchymal stem cell (MSC) differentiation can be influenced by biophysical stimuli imparted by the host scaffold. Yet, causal relationships linking…”
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Influence of statistical size effects on the plastic deformation of coronary stents by Grogan, J.A., Leen, S.B., McHugh, P.E.

“…The dimensions of coronary stent struts are similar to those of the metallic grains of their constituent alloys. This means that statistical size effects…”
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Measurement of the microstructural fracture toughness of cortical bone using indentation fracture by Mullins, L.P, Bruzzi, M.S, McHugh, P.E

“…Abstract The purpose of this work is to investigate the use of indentation fracture as a method of measuring toughness at the microscale in cortical bone…”
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Computational micromechanics of bioabsorbable magnesium stents by Grogan, J.A., Leen, S.B., McHugh, P.E.

“…Magnesium alloys are a promising candidate material for an emerging generation of absorbable metal stents. Due to its hexagonal-close-packed lattice structure…”
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Endothelial cell response to biomechanical forces under simulated vascular loading conditions by Punchard, M.A, Stenson-Cox, C, O’Cearbhaill, E.D, Lyons, E, Gundy, S, Murphy, L, Pandit, A, McHugh, P.E, Barron, V

“…Abstract In vivo , endothelial cells (EC) are constantly exposed to the haemodynamic forces (HF) of pressure, wall shear stress and hoop stress. The main aim…”
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Investigation of the failure behaviour of vertebral trabecular architectures under uni-axial compression and wedge action loading conditions by McDonnell, P, Harrison, N, McHugh, P.E

“…Abstract Vertebral wedge fractures are associated with combined compression and flexure loading and are the most common fracture type for human vertebrae. In…”
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Authors’ response to “comments on ‘measurement of the microstructural fracture toughness of cortical bone using indentation fracture’” by Mullins, L.P, Bruzzi, M.S, McHugh, P.E

“…(2007) a Berkovich tip was employed for hardness and Young's modulus measurement. Since the Berkovich tip is even blunter than the Vickers tip, the likelihood…”
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Dependence of mechanical properties of polyamide components on build parameters in the SLS process by Caulfield, B., McHugh, P.E., Lohfeld, S.

“…Customised properties of parts manufactured using the selective laser sintering process are achievable by variation of build parameters. The energy density,…”
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Finite element implementation of multiaxial continuum damage mechanics for plain and fretting fatigue by Zhang, T., McHugh, P.E., Leen, S.B.

“…► 3D FE implementation of continuum damage mechanics for multiaxial fatigue. ► Validation for uniaxial and notched fatigue and fretting fatigue for Ti–6Al–4V…”
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Numerical Simulation of Stent Angioplasty with Predilation: An Investigation into Lesion Constitutive Representation and Calcification Influence by Conway, C., McGarry, J. P., Edelman, E. R., McHugh, P. E.

“…It is acceptable clinical practice to predilate a severely occluded vessel to allow better positioning of endovascular stents, and while the impact of this…”
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Strain-gradient modelling of grain size effects on fatigue of CoCr alloy by Sweeney, C.A., O’Brien, B., Dunne, F.P.E., McHugh, P.E., Leen, S.B.

“…A strain-gradient crystal plasticity framework based on physical dislocation mechanisms is developed for simulation of the experimentally observed grain size…”
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A finite element methodology for wear–fatigue analysis for modular hip implants by Zhang, T., Harrison, N.M., McDonnell, P.F., McHugh, P.E., Leen, S.B.

“…Fretting of the stem-head joint in a prosthetic hip implant is investigated experimentally and computationally. An FE-based methodology for fretting…”
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An Experimental and Computational Investigation of Bone Formation in Mechanically Loaded Trabecular Bone Explants by Birmingham, E., Niebur, G. L., McNamara, L. M., McHugh, P. E.

“…Understanding how bone marrow multipotent stromal cells (MSCs) contribute to new bone formation and remodeling in vivo is of principal importance for informing…”
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Comparison of the implicit and explicit finite element methods using crystal plasticity by Harewood, F.J., McHugh, P.E.

“…The implicit finite element (FE) method can encounter numerical difficulties when solving non-linear quasi-static problems. The iterative approach employed may…”
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Computational study on the effect of contact geometry on fretting behaviour by Zhang, T., McHugh, P.E., Leen, S.B.

“…► Implementation and validation of an energy-based wear simulation method for Ti–6Al–4V. ► Prediction of effect of fretting wear on fretting crack nucleation…”
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A combined computational and experimental methodology to determine the adhesion properties of stent polymer coatings by Hopkins, C., McHugh, P.E., O’Dowd, N.P., Rochev, Y., McGarry, J.P.

“…•Novel computational–experimental methodology to characterise metal–polymer adhesion.•Identification of the key parameters that govern coating debonding during…”
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