Search Results - "McHugh, Neil J"

A systematic review and meta-analysis to inform cancer screening guidelines in idiopathic inflammatory myopathies by Oldroyd, Alexander G S, Allard, Andrew B, Callen, Jeffrey P, Chinoy, Hector, Chung, Lorinda, Fiorentino, David, George, Michael D, Gordon, Patrick, Kolstad, Kate, Kurtzman, Drew J B, Machado, Pedro M, McHugh, Neil J, Postolova, Anna, Selva-O’Callaghan, Albert, Schmidt, Jens, Tansley, Sarah, Vleugels, Ruth Ann, Werth, Victoria P, Aggarwal, Rohit

“…Abstract Objectives To identify clinical factors associated with cancer risk in the idiopathic inflammatory myopathies (IIMs) and to systematically review the…”
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Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset by Tansley, Sarah L, Betteridge, Zoe E, Shaddick, Gavin, Gunawardena, Harsha, Arnold, Katie, Wedderburn, Lucy R, McHugh, Neil J

“…Calcinosis is a major cause of morbidity in JDM and has previously been linked to anti-NXP2 autoantibodies, younger age at disease onset and more persistent…”
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A randomized placebo-controlled trial of methotrexate in psoriatic arthritis by KINGSLEY, Gabrielle H, KOWALCZYK, Anna, O'KEEFFE, Aidan G, MADDISON, Peter J, SCOTT, David L, TAYLOR, Helen, IBRAHIM, Fowzia, PACKHAM, Jonathan C, MCHUGH, Neil J, MULHERIN, Diarmuid M, KITAS, George D, CHAKRAVARTY, Kuntal, TOM, Brian D. M

“…MTX is widely used to treat synovitis in PsA without supporting trial evidence. The aim of our study was to test the value of MTX in the first large randomized…”
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Adult and juvenile dermatomyositis: are the distinct clinical features explained by our current understanding of serological subgroups and pathogenic mechanisms? by Tansley, Sarah L, McHugh, Neil J, Wedderburn, Lucy R

“…Adult and juvenile dermatomyositis share the hallmark features of pathognomic skin rash and muscle inflammation, but are heterogeneous disorders with a range…”
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Use of Laser Speckle Contrast Imaging to Assess Digital Microvascular Function in Primary Raynaud Phenomenon and Systemic Sclerosis: A Comparison Using the Raynaud Condition Score Diary by Pauling, John D, Shipley, Jacqueline A, Hart, Darren J, McGrogan, Anita, McHugh, Neil J

“…Evaluate objective assessment of digital microvascular function using laser speckle contrast imaging (LSCI) in a cross-sectional study of patients with primary…”
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The promise, perceptions, and pitfalls of immunoassays for autoantibody testing in myositis by Tansley, Sarah L, Snowball, Julia, Pauling, John D, Lissina, Anya, Kuwana, Masataka, Rider, Lisa G, Rönnelid, Johan, McHugh, Neil J

“…A myositis-specific autoantibody can now be identified in the majority of patients with myositis. They identify homogeneous patient subgroups and are key tools…”
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A Commercial Anti-TIF1γ ELISA Is Superior to Line and Dot Blot and Should Be Considered as Part of Routine Myositis-Specific Antibody Testing by Mulhearn, Ben, Li, Danyang, McMorrow, Fionnuala, Lu, Hui, McHugh, Neil J, Tansley, Sarah L

“…Anti-TIF1γ is an important autoantibody in the diagnosis of cancer-associated dermatomyositis and the most common autoantibody in juvenile onset…”
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The performance of the European League Against Rheumatism/American College of Rheumatology idiopathic inflammatory myopathies classification criteria in an expert-defined 10 year incident cohort by Parker, Matthew J S, Oldroyd, Alexander, Roberts, Mark E, Lilleker, James B, Betteridge, Zoe E, McHugh, Neil J, Herrick, Ariane L, Cooper, Robert G, Chinoy, Hector

“…Abstract Objectives To assess the performance of the EULAR/ACR idiopathic inflammatory myopathies (IIMs) classification criteria in a cohort of incident IIM…”
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Serum bone-turnover biomarkers are associated with the occurrence of peripheral and axial arthritis in psoriatic disease: a prospective cross-sectional comparative study by Jadon, Deepak R, Sengupta, Raj, Nightingale, Alison, Lu, Hui, Dunphy, Juliet, Green, Amelia, Elder, James T, Nair, Rajan P, Korendowych, Eleanor, Lindsay, Mark A, McHugh, Neil J

“…A recent systematic review identified four candidate serum-soluble bone-turnover biomarkers (dickkopf-1, Dkk-1; macrophage-colony stimulating factor, M-CSF;…”
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The diagnostic utility of autoantibodies in adult and juvenile myositis by Tansley, Sarah L., Betteridge, Zoe E., McHugh, Neil J.

“…PURPOSE OF REVIEWThe purpose of this study is to review recent advances in the diagnostic utility of autoantibodies in dermatomyositis. RECENT…”
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Transcriptional profiling identifies differential expression of long non-coding RNAs in Jo-1 associated and inclusion body myositis by Hamann, Philip D., Roux, Benoit T., Heward, James A., Love, Seth, McHugh, Neil J., Jones, Simon W., Lindsay, Mark A.

“…Myositis is characterised by muscle inflammation and weakness. Although generally thought to be driven by a systemic autoimmune response, increasing evidence…”
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Statin-induced necrotizing myositis – A discrete autoimmune entity within the “statin-induced myopathy spectrum” by Hamann, Philip D.H, Cooper, Robert G, McHugh, Neil J, Chinoy, Hector

“…Abstract Statin-induced necrotizing myositis is increasingly being recognised as part of the “statin-induced myopathy spectrum”. As in other immune-mediated…”
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Myositis Specific and Associated Autoantibodies in the Diagnosis and Management of Juvenile and Adult Idiopathic Inflammatory Myopathies by Tansley, Sarah L., McHugh, Neil J.

“…The idiopathic inflammatory myopathies are a heterogeneous group of disorders affecting both adults and children. Clinical features can include muscle…”
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Ro52, Myositis, and Interstitial Lung Disease by McHugh, Neil J

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Therapies for peripheral joint disease in psoriatic arthritis. A systematic review by Soriano, Enrique R, McHugh, Neil J

“…Traditional drug treatments for psoriatic arthritis (PsA) include nonsteroidal antiinflammatory agents (NSAID) and disease modifying antirheumatic drugs…”
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Comment on: The temporal relationship between cancer and adult onset anti-transcriptional intermediary factor 1 antibody–positive dermatomyositis: Reply by Oldroyd, Alexander, Sergeant, Jamie C, New, R Paul, McHugh, Neil J, Betteridge, Zoe, Lamb, Janine A, Ollier, William E, Cooper, Robert G, Chinoy, Hector

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Investigation of myositis and scleroderma specific autoantibodies in patients with lung cancer by Betteridge, Zoe E, Priest, Lynsey, Cooper, Robert G, McHugh, Neil J, Blackhall, Fiona, Lamb, Janine A

“…The close temporal association between onset of some connective tissue diseases and cancer suggests a paraneoplastic association. Adult patients with…”
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Autoantibodies in myositis by McHugh, Neil J., Tansley, Sarah L.

“…Key Points Myositis-specific autoantibodies (MSAs) are present in the majority of juvenile and adult cases of idiopathic inflammatory myopathy and are largely…”
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Associations of erosive arthritis with anti-cyclic citrullinated peptide antibodies and MHC Class II alleles in systemic lupus erythematosus by CHAN, Madelynn T, OWEN, Patricia, DUNPHY, Juliet, COX, Beverley, CARMICHAEL, Charlotte, KORENDOWYCH, Eleanor, MCHUGH, Neil J

“…OBJECTIVE: To determine the associations of erosive arthritis (EA) with anti-cyclic citrullinated peptide (anti-CCP) antibodies and major histocompatibility…”
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Polymorphisms in IL-1B Distinguish between Psoriasis of Early and Late Onset by Hébert, Harry L., Bowes, John, Smith, Rhodri L., McHugh, Neil J., Barker, Jonathan N.W.N., Griffiths, Christopher E.M., Barton, Anne, Warren, Richard B.

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