Search Results - "McHugh, B"

Hippocampal synaptic plasticity, spatial memory and anxiety by Bannerman, David M., Sprengel, Rolf, Sanderson, David J., McHugh, Stephen B., Rawlins, J. Nicholas P., Monyer, Hannah, Seeburg, Peter H.

“…In this Perspective, Seeburg and colleagues re-examine the role of the hippocampus in spatial learning in light of recent findings. They also suggest that the…”
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High frequencies of theropod bite marks provide evidence for feeding, scavenging, and possible cannibalism in a stressed Late Jurassic ecosystem by Drumheller, Stephanie K, McHugh, Julia B, Kane, Miriam, Riedel, Anja, D'Amore, Domenic C

“…Bite marks provide direct evidence for trophic interactions and competition in the fossil record. However, variations in paleoecological dynamics, such as…”
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Adult-born dentate granule cells promote hippocampal population sparsity by McHugh, Stephen B., Lopes-dos-Santos, Vítor, Gava, Giuseppe P., Hartwich, Katja, Tam, Shu K. E., Bannerman, David M., Dupret, David

“…The dentate gyrus (DG) gates neocortical information flow to the hippocampus. Intriguingly, the DG also produces adult-born dentate granule cells (abDGCs)…”
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Activating FGFR2-RAS-BRAF mutations in ameloblastoma by Brown, Noah A, Rolland, Delphine, McHugh, Jonathan B, Weigelin, Helmut C, Zhao, Lili, Lim, Megan S, Elenitoba-Johnson, Kojo S J, Betz, Bryan L

“…Ameloblastoma is an odontogenic neoplasm whose overall mutational landscape has not been well characterized. We sought to characterize pathogenic mutations in…”
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EWSR1-NFATC2 Translocation-associated Sarcoma Clinicopathologic Findings in a Rare Aggressive Primary Bone or Soft Tissue Tumor by Wang, Grace Y, Thomas, Dafydd G, Davis, Jessica L, Ng, Tony, Patel, Rajiv M, Harms, Paul W, Betz, Bryan L, Schuetze, Scott M, McHugh, Jonathan B, Horvai, Andrew E, Cho, Soo-Jin, Lucas, David R

“…In recent years, a novel small round cell sarcoma harboring EWSR1-NFATC2 translocation with immunomorphologic overlap with Ewing sarcoma (ES), myoepithelial…”
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Early HPV ctDNA Kinetics and Imaging Biomarkers Predict Therapeutic Response in p16+ Oropharyngeal Squamous Cell Carcinoma by Cao, Yue, Haring, Catherine T, Brummel, Collin, Bhambhani, Chandan, Aryal, Madhava, Lee, Choonik, Heft Neal, Molly, Bhangale, Apurva, Gu, Wenjin, Casper, Keith, Malloy, Kelly, Sun, Yilun, Shuman, Andrew, Prince, Mark E, Spector, Matthew E, Chinn, Steven, Shah, Jennifer, Schonewolf, Caitlin, McHugh, Jonathan B, Mills, Ryan E, Tewari, Muneesh, Worden, Francis P, Swiecicki, Paul L, Mierzwa, Michelle, Brenner, J Chad

“…In locally advanced p16+ oropharyngeal squamous cell carcinoma (OPSCC), (i) to investigate kinetics of human papillomavirus (HPV) circulating tumor DNA (ctDNA)…”
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Biphenotypic Sinonasal Sarcoma: A Review and Update by Carter, Cody S, East, Ellen G, McHugh, Jonathan B

“…Biphenotypic sinonasal sarcoma (BSNS) is a rare, slow-growing soft tissue sarcoma of the sinonasal tract, typically presenting with nonspecific obstructive…”
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Extensive Survey of STAT6 Expression in a Large Series of Mesenchymal Tumors by Demicco, Elizabeth G., Harms, Paul W., Patel, Rajiv M., Smith, Steven C., Ingram, Davis, Torres, Keila, Carskadon, Shannon L., Camelo-Piragua, Sandra, McHugh, Jonathan B., Siddiqui, Javed, Palanisamy, Nallasivam, Lucas, David R., Lazar, Alexander J., Wang, Wei-Lien

“…Objectives: Expression of strong nuclear STAT6 is thought to be a specific marker for solitary fibrous tumors (SFTs). Little is known about subtle expression…”
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High-Frequency Targetable EGFR Mutations in Sinonasal Squamous Cell Carcinomas Arising from Inverted Sinonasal Papilloma by Udager, Aaron M, Rolland, Delphine C M, McHugh, Jonathan B, Betz, Bryan L, Murga-Zamalloa, Carlos, Carey, Thomas E, Marentette, Lawrence J, Hermsen, Mario A, DuRoss, Kathleen E, Lim, Megan S, Elenitoba-Johnson, Kojo S J, Brown, Noah A

“…Inverted sinonasal papilloma (ISP) is a locally aggressive neoplasm associated with sinonasal squamous cell carcinoma (SNSCC) in 10% to 25% of cases. To date,…”
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Hippocampal NMDA receptors and anxiety: At the interface between cognition and emotion by Barkus, Christopher, McHugh, Stephen B., Sprengel, Rolf, Seeburg, Peter H., Rawlins, J. Nicholas P., Bannerman, David M.

“…David De Wied had a fundamental interest in the brain and behaviour, with a particular interest in the interface between cognition and emotion, and how…”
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Aversive prediction error signals in the amygdala by McHugh, Stephen B, Barkus, Christopher, Huber, Anna, Capitão, Liliana, Lima, João, Lowry, John P, Bannerman, David M

“…Prediction error signals are fundamental to learning. Here, in mice, we show that aversive prediction signals are found in the hemodynamic responses and theta…”
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Impact of Perineural Invasion in the Pathologically N0 Neck in Oral Cavity Squamous Cell Carcinoma by Chinn, Steven B., Spector, Matthew E., Bellile, Emily L., McHugh, Jonathan B., Gernon, Thomas J., Bradford, Carol R., Wolf, Gregory T., Eisbruch, Avraham, Chepeha, Douglas B.

“…Objective Patients with oral cavity squamous cell carcinoma (OCSCC) undergo adjuvant radiation for pathologically high-risk features including positive nodal…”
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A distinctive, low‐grade oncocytic fumarate hydratase‐deficient renal cell carcinoma, morphologically reminiscent of succinate dehydrogenase‐deficient renal cell carcinoma by Smith, Steven C, Sirohi, Deepika, Ohe, Chisato, McHugh, Jonathan B, Hornick, Jason L, Kalariya, Jigna, Karia, Sushil, Snape, Katie, Hodgson, Shirley V, Cani, Andi K, Hovelson, Daniel, Luthringer, Daniel J, Martignoni, Guido, Chen, Ying‐Bei, Tomlins, Scott A, Mehra, Rohit, Amin, Mahul B

“…Aims Fumarate hydratase (FH)‐deficient renal cell carcinoma (RCC) is a high‐grade, aggressive tubulopapillary carcinoma, arising predominantly in the setting…”
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Ablating adult neurogenesis in the rat has no effect on spatial processing: evidence from a novel pharmacogenetic model by Groves, James O, Leslie, Isla, Huang, Guo-Jen, McHugh, Stephen B, Taylor, Amy, Mott, Richard, Munafò, Marcus, Bannerman, David M, Flint, Jonathan

“…The function of adult neurogenesis in the rodent brain remains unclear. Ablation of adult born neurons has yielded conflicting results about emotional and…”
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Relationships between contrast-enhanced computed tomography features of hard palate cancer and pathological depth of invasion by Baba, Akira, Kurokawa, Ryo, Kurokawa, Mariko, McHugh, Jonathan B., Hines, Cisley, Ota, Yoshiaki, Srinivasan, Ashok

“…OBJECTIVEThe study aimed to determine the relationships between contrast-enhanced computed tomography (CECT) features of hard palate cancer (radiological depth…”
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TP53 mutations and CDKN2A mutations/deletions are highly recurrent molecular alterations in the malignant progression of sinonasal papillomas by Brown, Noah A., Plouffe, Komal R., Yilmaz, Osman, Weindorf, Steven C., Betz, Bryan L., Carey, Thomas E., Seethala, Raja R., McHugh, Jonathan B., Tomlins, Scott A., Udager, Aaron M.

“…Sinonasal papillomas are benign epithelial tumors of the sinonasal tract that are associated with a synchronous or metachronous sinonasal carcinoma in a subset…”
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Primary mesenchymal chondrosarcoma of the lung by Perry, William R., McHugh, Jonathan B., Konopka, Kristine E.

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Increased Serotonin Transporter Expression Reduces Fear and Recruitment of Parvalbumin Interneurons of the Amygdala by Bocchio, Marco, Fucsina, Giulia, Oikonomidis, Lydia, McHugh, Stephen B, Bannerman, David M, Sharp, Trevor, Capogna, Marco

“…Genetic association studies suggest that variations in the 5-hydroxytryptamine (5-HT; serotonin) transporter (5-HTT) gene are associated with susceptibility to…”
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Correlation of Crtc1/3-Maml2 fusion status, grade and survival in mucoepidermoid carcinoma by Birkeland, Andrew C, Foltin, Susan K, Michmerhuizen, Nicole L, Hoesli, Rebecca C, Rosko, Andrew J, Byrd, Serena, Yanik, Megan, Nor, Jacques E, Bradford, Carol R, Prince, Mark E, Carey, Thomas E, McHugh, Jonathan B, Spector, Matthew E, Brenner, J. Chad

“…Highlights • We calculated gene fusion rates in patients with mucoepidermoid carcinoma. • This is among the largest mucoepidermoid carcinoma cohorts to date. •…”
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Proportion of CD4 and CD8 tumor infiltrating lymphocytes predicts survival in persistent/recurrent laryngeal squamous cell carcinoma by Hoesli, Rebecca, Birkeland, Andrew C., Rosko, Andrew J., Issa, Mohamad, Chow, Kelsey L., Michmerhuizen, Nicole L., Mann, Jacqueline E., Chinn, Steven B., Shuman, Andrew G., Prince, Mark E., Wolf, Gregory T., Bradford, Carol R., McHugh, Jonathan B., Brenner, J. Chad, Spector, Matthew E.

“…•We explored the prognostic role of biomarkers in recurrent LSCC after RT/CRT.•Immunohistology included CD4, CD8, PDL-1, p16, CD31, Vimentin, EGFR, and…”
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