Search Results - "McGuire, P K"

Acute effects of a single, oral dose of d9-tetrahydrocannabinol (THC) and cannabidiol (CBD) administration in healthy volunteers by Martin-Santos, R, Crippa, J A, Batalla, A, Bhattacharyya, S, Atakan, Z, Borgwardt, S, Allen, P, Seal, M, Langohr, K, Farré, M, Zuardi, A W, McGuire, P K

“…Animal and humans studies suggest that the two main constituents of cannabis sativa, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) have quite…”
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Multimodal meta-analysis of structural and functional brain changes in first episode psychosis and the effects of antipsychotic medication by RADUA, J, BORGWARDT, S, CRESCINI, A, MATAIX-COLS, D, MEYER-LINDENBERG, A, MCGUIRE, P. K, FUSAR-POLI, P

“…Structure and function in the human brain are closely related. At the onset of psychosis, brain imaging studies have identified robust changes in brain…”
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Negative psychotic symptoms and impaired role functioning predict transition outcomes in the at-risk mental state: a latent class cluster analysis study by Valmaggia, L R, Stahl, D, Yung, A R, Nelson, B, Fusar-Poli, P, McGorry, P D, McGuire, P K

“…Many research groups have attempted to predict which individuals with an at-risk mental state (ARMS) for psychosis will later develop a psychotic disorder…”
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Outreach and support in South London (OASIS), 2001–2011: Ten years of early diagnosis and treatment for young individuals at high clinical risk for psychosis by Fusar-Poli, P, Byrne, M, Badger, S, Valmaggia, L.R, McGuire, P.K

“…Abstract Introduction Prevention of psychosis has become a major objective of modern clinical psychiatry. An increasing number of new services have been…”
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Neuroimaging predictors of transition to psychosis—A systematic review and meta-analysis by Smieskova, R., Fusar-Poli, P., Allen, P., Bendfeldt, K., Stieglitz, R.D., Drewe, J., Radue, E.W., McGuire, P.K., Riecher-Rössler, A., Borgwardt, S.J.

“…In early stage psychosis research the identification of neurobiological correlates of vulnerability to schizophrenia is an important hurdle. We systematically…”
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Cannabis use and transition to psychosis in people at ultra-high risk by Valmaggia, L R, Day, F L, Jones, C, Bissoli, S, Pugh, C, Hall, D, Bhattacharyya, S, Howes, O, Stone, J, Fusar-Poli, P, Byrne, M, McGuire, P K

“…Cannabis use is associated with an increased risk of developing a psychotic disorder but the temporal relationship between cannabis use and onset of illness is…”
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Autoantibodies to central nervous system neuronal surface antigens: psychiatric symptoms and psychopharmacological implications by Pollak, T. A., Beck, K., Irani, S. R., Howes, O. D., David, A. S., McGuire, P. K.

“…Rationale Autoantibodies to central nervous system (CNS) neuronal surface antigens have been described in association with autoimmune encephalopathies which…”
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Altered connections on the road to psychopathy by Craig, M C, Catani, M, Deeley, Q, Latham, R, Daly, E, Kanaan, R, Picchioni, M, McGuire, P K, Fahy, T, Murphy, D G M

“…Psychopathy is strongly associated with serious criminal behaviour (for example, rape and murder) and recidivism. However, the biological basis of psychopathy…”
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Schizotypy and brain structure: a voxel-based morphometry study by Modinos, G, Mechelli, A, Ormel, J, Groenewold, N A, Aleman, A, McGuire, P K

“…Schizotypy is conceptualized as a subclinical manifestation of the same underlying biological factors that give rise to schizophrenia and other schizophrenia…”
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Interpersonal sensitivity in the at-risk mental state for psychosis by Masillo, A, Day, F, Laing, J, Howes, O, Fusar-Poli, P, Byrne, M, Bhattacharyya, S, Fiori Nastro, P, Girardi, P, McGuire, P K, Valmaggia, L R

“…Interpersonal sensitivity is a personality trait described as excessive awareness of both the behaviour and feelings of others. Although interpersonal…”
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Delusion formation and reasoning biases in those at clinical high risk for psychosis by Broome, M. R., Johns, L. C., Valli, I., Woolley, J. B., Tabraham, P., Brett, C., Valmaggia, L., Peters, E., Garety, P. A., McGuire, P. K.

“…Cognitive models propose that faulty appraisal of anomalous experiences is critical in developing psychosis, particularly delusions. A data gathering bias may…”
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Protein kinase B (AKT1) genotype mediates sensitivity to cannabis-induced impairments in psychomotor control by Bhattacharyya, S, Iyegbe, C, Atakan, Z, Martin-Santos, R, Crippa, J A, Xu, X, Williams, S, Brammer, M, Rubia, K, Prata, D, Collier, D A, McGuire, P K

“…What determines inter-individual variability to impairments in behavioural control that may underlie road-traffic accidents, and impulsive and violent…”
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Economic impact of early intervention in people at high risk of psychosis by Valmaggia, L R, McCrone, P, Knapp, M, Woolley, J B, Broome, M R, Tabraham, P, Johns, L C, Prescott, C, Bramon, E, Lappin, J, Power, P, McGuire, P K

“…Despite the increasing development of early intervention services for psychosis, little is known about their cost-effectiveness. We assessed the…”
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Effect of symptoms on executive function in bipolar illness by Dixon, T, Kravariti, E, Frith, C, Murray, R M, McGuire, P K

“…The relationship between cognitive function and symptomatology in bipolar disorder is unclear. This study assessed executive function during the manic,…”
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The role of metacognitive beliefs in determining the impact of anomalous experiences: a comparison of help-seeking and non-help-seeking groups of people experiencing psychotic-like anomalies by Brett, C M C, Johns, L C, Peters, E P, McGuire, P K

“…Current psychological models of psychotic symptoms suggest that metacognitive beliefs impact on an individual's appraisal of anomalous experiences, and thereby…”
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Longitudinal follow-up of cavum septum pellucidum and adhesio interthalamica alterations in first-episode psychosis: a population-based MRI study by Trzesniak, C, Schaufelberger, M S, Duran, F L S, Santos, L C, Rosa, P G P, McGuire, P K, Murray, R M, Scazufca, M, Menezes, P R, Hallak, J E C, Crippa, J A S, Busatto, G F

“…Neurodevelopmental alterations have been described inconsistently in psychosis probably because of lack of standardization among studies. The aim of this study…”
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Reversed lateralization of temporal activation during speech production in thought disordered patients with schizophrenia by Kircher, T T J, Liddle, P F, Brammer, M J, Williams, S C R, Murray, R M, McGuire, P K

“…Formal thought disorder is a core symptom of schizophrenia. It is associated with a reversed lateralization of the superior temporal cortex volume, an area…”
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Affective modulation of external misattribution bias in source monitoring in schizophrenia by Costafreda, S G, Brébion, G, Allen, P, McGuire, P K, Fu, C H Y

“…Schizophrenic patients tend to attribute internal events to external agents, a bias that may be linked to positive symptoms. We investigated the effect of…”
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Lack of progression of brain abnormalities in first-episode psychosis: a longitudinal magnetic resonance imaging study by Schaufelberger, M S, Lappin, J M, Duran, F L S, Rosa, P G P, Uchida, R R, Santos, L C, Murray, R M, McGuire, P K, Scazufca, M, Menezes, P R, Busatto, G F

“…Some neuroimaging studies have supported the hypothesis of progressive brain changes after a first episode of psychosis. We aimed to determine whether (i)…”
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Outreach and Support in South London (OASIS). Outcomes of non-attenders to a service for people at high risk of psychosis: the case for a more assertive approach to assessment by Green, C E L, McGuire, P K, Ashworth, M, Valmaggia, L R

“…International agreement dictates that clients must be help-seeking before any assessment or intervention can be implemented by an 'at-risk service'. Little is…”
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