Search Results - "McGuire, P"

Acute effects of a single, oral dose of d9-tetrahydrocannabinol (THC) and cannabidiol (CBD) administration in healthy volunteers by Martin-Santos, R, Crippa, J A, Batalla, A, Bhattacharyya, S, Atakan, Z, Borgwardt, S, Allen, P, Seal, M, Langohr, K, Farré, M, Zuardi, A W, McGuire, P K

“…Animal and humans studies suggest that the two main constituents of cannabis sativa, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) have quite…”
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Neuroimaging studies of GABA in schizophrenia: a systematic review with meta-analysis by Egerton, A, Modinos, G, Ferrera, D, McGuire, P

“…Data from animal models and from postmortem studies suggest that schizophrenia is associated with brain GABAergic dysfunction. The extent to which this is…”
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Multimodal meta-analysis of structural and functional brain changes in first episode psychosis and the effects of antipsychotic medication by RADUA, J, BORGWARDT, S, CRESCINI, A, MATAIX-COLS, D, MEYER-LINDENBERG, A, MCGUIRE, P. K, FUSAR-POLI, P

“…Structure and function in the human brain are closely related. At the onset of psychosis, brain imaging studies have identified robust changes in brain…”
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Deconstructing vulnerability for psychosis: Meta-analysis of environmental risk factors for psychosis in subjects at ultra high-risk by Fusar-Poli, P, Tantardini, M, De Simone, S, Ramella-Cravaro, V, Oliver, D, Kingdon, J, Kotlicka-Antczak, M, Valmaggia, L, Lee, J, Millan, M.J, Galderisi, S, Balottin, U, Ricca, V, McGuire, P

“…Abstract Background Subjects at ultra high-risk (UHR) for psychosis have an enhanced vulnerability to develop the disorder but the risk factors accounting for…”
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Impacts of extreme summers on European ecosystems: a comparative analysis of 2003, 2010 and 2018 by Bastos, A, Fu, Z, Ciais, P, Friedlingstein, P, Sitch, S, Pongratz, J, Weber, U, Reichstein, M, Anthoni, P, Arneth, A, Haverd, V, Jain, A, Joetzjer, E, Knauer, J, Lienert, S, Loughran, T, McGuire, P C, Obermeier, W, Padrón, R S, Shi, H, Tian, H, Viovy, N, Zaehle, S

“…In Europe, three widespread extreme summer drought and heat (DH) events have occurred in 2003, 2010 and 2018. These events were comparable in magnitude but…”
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Direct and seasonal legacy effects of the 2018 heat wave and drought on European ecosystem productivity by Bastos, A, Ciais, P, Friedlingstein, P, Sitch, S, Pongratz, J, Fan, L, Wigneron, J P, Weber, U, Reichstein, M, Fu, Z, Anthoni, P, Arneth, A, Haverd, V, Jain, A K, Joetzjer, E, Knauer, J, Lienert, S, Loughran, T, McGuire, P C, Tian, H, Viovy, N, Zaehle, S

“…In summer 2018, central and northern Europe were stricken by extreme drought and heat (DH2018). The DH2018 differed from previous events in being preceded by…”
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Neuroanatomical Maps of Psychosis Onset: Voxel-wise Meta-Analysis of Antipsychotic-Naive VBM Studies by FUSAR-POLI, Paolo, RADUA, Joaquim, MCGUIRE, Philip, BORGWARDT, Stefan

“…Despite impressive advancements in early interventions in psychosis, there is an urgent need of robust neurobiological markers to improve the predictive value…”
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Long-term validity of the At Risk Mental State (ARMS) for predicting psychotic and non-psychotic mental disorders by Fusar-Poli, P, Rutigliano, G, Stahl, D, Davies, C, De Micheli, A, Ramella-Cravaro, V, Bonoldi, I, McGuire, P

“…Abstract Background The long-term clinical validity of the At Risk Mental State (ARMS) for the prediction of non-psychotic mental disorders is unknown. Methods…”
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Negative psychotic symptoms and impaired role functioning predict transition outcomes in the at-risk mental state: a latent class cluster analysis study by Valmaggia, L R, Stahl, D, Yung, A R, Nelson, B, Fusar-Poli, P, McGorry, P D, McGuire, P K

“…Many research groups have attempted to predict which individuals with an at-risk mental state (ARMS) for psychosis will later develop a psychotic disorder…”
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Social Support Moderates Effects of Natural Disaster Exposure on Depression and Posttraumatic Stress Disorder Symptoms: Effects for Displaced and Nondisplaced Residents by McGuire, Adam P., Gauthier, Jami M., Anderson, Lisa M., Hollingsworth, David W., Tracy, Melissa, Galea, Sandro, Coffey, Scott F.

“…Social support is a known protective factor against the negative psychological impact of natural disasters. Most past research has examined how the effects of…”
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Cannabis-associated psychosis: Neural substrate and clinical impact by Murray, R.M., Englund, A., Abi-Dargham, A., Lewis, D.A., Di Forti, M., Davies, C., Sherif, M., McGuire, P., D'Souza, D.C.

“…Prospective epidemiological studies have consistently demonstrated that cannabis use is associated with an increased subsequent risk of both psychotic symptoms…”
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Outreach and support in South London (OASIS), 2001–2011: Ten years of early diagnosis and treatment for young individuals at high clinical risk for psychosis by Fusar-Poli, P, Byrne, M, Badger, S, Valmaggia, L.R, McGuire, P.K

“…Abstract Introduction Prevention of psychosis has become a major objective of modern clinical psychiatry. An increasing number of new services have been…”
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Exploring the trajectory and correlates of social isolation for veterans across a 6-month period during COVID-19 by McGuire, Adam P, Elmore, Colby, Szabo, Yvette Z, Kurz, A Solomon, Mendoza, Corina, Umucu, Emre, Creech, Suzannah K

“…Social isolation is a relevant problem for veterans who are at risk for disengaging from others as a function of transition stress from military life to…”
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Neuroimaging predictors of transition to psychosis—A systematic review and meta-analysis by Smieskova, R., Fusar-Poli, P., Allen, P., Bendfeldt, K., Stieglitz, R.D., Drewe, J., Radue, E.W., McGuire, P.K., Riecher-Rössler, A., Borgwardt, S.J.

“…In early stage psychosis research the identification of neurobiological correlates of vulnerability to schizophrenia is an important hurdle. We systematically…”
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Effects of short-term cannabidiol treatment on response to social stress in subjects at clinical high risk of developing psychosis by Appiah-Kusi, E., Petros, N., Wilson, R., Colizzi, M., Bossong, M. G., Valmaggia, L., Mondelli, V., McGuire, P., Bhattacharyya, S.

“…Rationale Stress is a risk factor for psychosis and treatments which mitigate its harmful effects are needed. Cannabidiol (CBD) has antipsychotic and…”
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The effects of antipsychotics on the brain: what have we learnt from structural imaging of schizophrenia?--a systematic review by Smieskova, R, Fusar-Poli, P, Allen, P, Bendfeldt, K, Stieglitz, R D, Drewe, J, Radue, E W, McGuire, P K, Riecher-Rössler, A, Borgwardt, S J

“…Despite a large number of neuroimaging studies in schizophrenia reporting subtle brain abnormalities, we do not know to what extent such abnormalities reflect…”
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Is paliperidone palmitate more effective than other long-acting injectable antipsychotics? by Patel, R, Chesney, E, Taylor, M, Taylor, D, McGuire, P

“…Paliperidone palmitate is one of the most widely prescribed long-acting injectable (LAI) antipsychotics in the UK. However, it is relatively expensive and…”
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Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: a PET study by Howes, O, Bose, S, Turkheimer, F, Valli, I, Egerton, A, Stahl, D, Valmaggia, L, Allen, P, Murray, R, McGuire, P

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Cannabis use and transition to psychosis in people at ultra-high risk by Valmaggia, L R, Day, F L, Jones, C, Bissoli, S, Pugh, C, Hall, D, Bhattacharyya, S, Howes, O, Stone, J, Fusar-Poli, P, Byrne, M, McGuire, P K

“…Cannabis use is associated with an increased risk of developing a psychotic disorder but the temporal relationship between cannabis use and onset of illness is…”
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Autoantibodies to central nervous system neuronal surface antigens: psychiatric symptoms and psychopharmacological implications by Pollak, T. A., Beck, K., Irani, S. R., Howes, O. D., David, A. S., McGuire, P. K.

“…Rationale Autoantibodies to central nervous system (CNS) neuronal surface antigens have been described in association with autoimmune encephalopathies which…”
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