Search Results - "McGuire, Ashlyn"
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The multifunctional globin dehaloperoxidase strikes again: Simultaneous peroxidase and peroxygenase mechanisms in the oxidation of EPA pollutants
Published in Archives of biochemistry and biophysics (30-09-2019)“…The multifunctional catalytic hemoglobin dehaloperoxidase (DHP) from the terebellid polychaete Amphitrite ornata was found to catalyze the H2O2-dependent…”
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Journal Article -
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Peroxidase versus Peroxygenase Activity: Substrate Substituent Effects as Modulators of Enzyme Function in the Multifunctional Catalytic Globin Dehaloperoxidase
Published in Biochemistry (Easton) (31-07-2018)“…The dehaloperoxidase-hemoglobin (DHP) from the terebellid polychaete Amphitrite ornata is a multifunctional hemoprotein that catalyzes the oxidation of a wide…”
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Journal Article -
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Mössbauer studies of the ferryl, ferrous and ferric states of dehaloperoxidase from A. ornata
Published in Journal of inorganic biochemistry (01-09-2022)“…Dehaloperoxidase (DHP) is a multi-functional catalytic globin from the marine worm A. ornata, whose physiological functions include oxygen transport and…”
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Lipid-Encapsulated mRNAs Encoding Complex Fusion Proteins Potentiate Antitumor Immune Responses
Published in Cancer research (Chicago, Ill.) (15-05-2024)“…Lipid nanoparticle (LNP)-encapsulated mRNA has been used for in vivo production of several secreted protein classes, such as IgG, and has enabled the…”
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LIGHT (TNFSF14) Costimulation Enhances Myeloid Cell Activation and Antitumor Immunity in the Setting of PD-1/PD-L1 and TIGIT Checkpoint Blockade
Published in The Journal of immunology (1950) (01-08-2022)“…Coinhibition of TIGIT (T cell immunoreceptor with Ig and ITIM domains) and PD-1/PD-L1 (PD-1/L1) may improve response rates compared with monotherapy PD-1/L1…”
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Journal Article -
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When a Hemoglobin Acts as a Catalytic Enzyme: Mechanistic Studies of Dehaloperoxidase
Published 01-01-2020“…The marine hemoglobin dehaloperoxidase (DHP) from the terebellid polychaete Amphitrite ornata is the first multifunctional hemoprotein with both an…”
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Dissertation