Search Results - "McGuinness, Michael"
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Supplementing a Traditional Human Gross Anatomy Course with Ultrasound Training
Published in The FASEB journal (01-04-2019)“…Advances in scientific knowledge and advances in treatments and diagnostic tools has placed an increase in demand with regard to basic science and clinical…”
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Double Superior Vena Cava: a Cadaveric Case Report
Published in The FASEB journal (01-04-2017)“…Abstract only The heart and mediastinum of a 92 year old male cadaver with a double superior vena cava was dissected and examined in detail. In most…”
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Relationship of Physical Examination Findings and Self-Reported Symptom Severity and Physical Function in Patients With Degenerative Lumbar Conditions
Published in Physical therapy (01-02-2005)“…Limited data are available to assist clinicians in clinical decision making. The purpose of this study was to examine the relationships of symptom provocation…”
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A Simulation Game for an Introductory Course in International Business
Published in Journal of teaching in international business (10-12-2004)“…An international business simulation game designed for an introductory International Business course. The simulation game allows for student decision making…”
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MiR‐486a‐5p Exerts Cardioprotection Against Ischemia Repefusion via Suppression of PDCD4
Published in The FASEB journal (01-04-2019)“…Extracellular vesicle (EV) derived from mesenchymal stem cells (MSCs) have been demonstrated to be a critical component for cardioprotection against myocardial…”
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MiR‐486a‐5p Alters Cell Survival in Ischemia‐Reperfusion Induced Myocardial Injury
Published in The FASEB journal (01-04-2018)“…Previous work in our lab has shown that mesenchymal stem cells (MSC)‐derived exosomes protect cardiomyocytes from ischemia‐reperfusion (I/R) induced myocardial…”
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Tackling Challenging Data Integrity Topics in 2020: Update on Good Clinical Practice Perspectives from the US FDA and MHRA UK
Published in Clinical pharmacology and therapeutics (01-07-2022)“…With the globalization of clinical trials, regulators have increased collaboration to evaluate the adequacy of clinical trial conduct and to optimize…”
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Estrogen regulation of monocyte and endothelial cell adhesion
Published in The FASEB journal (01-04-2012)“…Abstract only Estrogens may regulate cell adhesion molecules and alter monocyte binding to endothelial cells. These actions are mediated by receptors present…”
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MSC‐Derived Exosomes Deliver Cardioprotective miR‐21
Published in The FASEB journal (01-04-2017)“…Abstract only Mesenchymal stem cell (MSC) transplantation has been shown to improve outcomes after myocardial infarction (MI) in animal models and in man…”
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Changes in cytoplasmic calcium in endothelial cells and monocytes treated with estrogen (LB58)
Published in The FASEB journal (01-04-2014)“…Estrogen is a hormone which exerts its effects in different physiological processes including the initiation and progress of inflammation. In addition to…”
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MSC Exosomes Deliver Cardioprotective miR‐21
Published in The FASEB journal (01-04-2016)“…Abstract only Introduction Mesenchymal stem cell (MSC) transplantation has been shown to improve outcomes including infarct size in animal models of myocardial…”
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Coordinated Post-transcriptional Regulation of Hsp70.3 Gene Expression by MicroRNA and Alternative Polyadenylation
Published in The Journal of biological chemistry (26-08-2011)“…Heat shock protein 70 (Hsp70) is well documented to possess general cytoprotective properties in protecting the cell against stressful and noxious stimuli. We…”
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2020 White Paper on Recent Issues in Bioanalysis: BMV of Hybrid Assays, Acoustic MS, HRMS, Data Integrity, Endogenous Compounds, Microsampling and Microbiome
Published in Bioanalysis (01-02-2021)“…The 14 edition of the Workshop on Recent Issues in Bioanalysis (14 WRIB) was held virtually on June 15–29, 2020 with an attendance of over 1000 representatives…”
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The stress-induced heat shock protein 70.3 expression is regulated by a dual-component mechanism involving alternative polyadenylation and HuR
Published in Biochimica et biophysica acta (01-06-2015)“…Heat shock protein 70.3 (Hsp70.3) expression increases in response to cellular stress and plays a cytoprotective role. We have previously shown that Hsp70.3…”
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2020 White Paper on Recent Issues in Bioanalysis: BAV Guidance, CLSI H62, Biotherapeutics Stability, Parallelism Testing, CyTOF and Regulatory Feedback
Published in Bioanalysis (01-03-2021)“…The 14 edition of the Workshop on Recent Issues in Bioanalysis (14 WRIB) was held virtually on June 15-29, 2020 with an attendance of over 1000 representatives…”
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Functional estrogen receptors in the nucleus and plasma membrane of TM3 Leydig cell line
Published in The FASEB journal (01-04-2010)“…Estrogen receptor (ER) expression and function were examined using the TM3 Leydig cell line. Both ERα and ERβ were detected using Western blot analysis and…”
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Identification of regulatory RNA binding proteins that mediate alternative polyadenylation in cardiac myocytes
Published in The FASEB journal (01-04-2013)“…Abstract only Introduction Cardiovascular disease is the leading cause of death in the US with coronary heart disease (ischemia/reperfusion; I/R injury)…”
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Alternative polyadenylation mediated shortening of the Hsp70.3 3′UTR increases polyribosome loading of the mRNA transcript
Published in The FASEB journal (01-04-2013)“…Abstract only Introduction Heat shock protein 70.3 (Hsp70.3) expression is increased in response to cellular stress and plays a cytoprotective role, including…”
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The future of world health: The new world order and international health
Published in BMJ (10-05-1997)Get full text
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