Search Results - "McGrogan, M"
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Transplantation of cultured human neuronal cells for patients with stroke
Published in Neurology (22-08-2000)“…Transplantation of cultured neuronal cells is safe in animal models and improves motor and cognitive deficits in rats with stroke. The authors studied the…”
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A comparison of dopaminergic cells from the human NTera2/D1 cell line transplanted into the hemiparkinsonian rat
Published in Life sciences (1973) (19-07-2007)“…Human NT cells derived from the NTera2/D1 cell line express a dopaminergic phenotype making them an attractive vehicle to supply dopamine to the depleted…”
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3
Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS-mediated cell activation
Published in The Journal of biological chemistry (01-07-1994)“…We have previously shown that human bactericidal/permeability-increasing protein (BPI) is able to inhibit serum-dependent lipopolysaccharide (LPS)-mediated…”
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4
cDNA Cloning and Expression of Murine Macrophage Colony-Stimulating Factor from L929 Cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1988)“…A 4-kilobase and a 2-kilobase cDNA clone encoding a murine macrophage colony-stimulating factor have been isolated. Except for 2 amino acid residue…”
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5
Protease specificity and heparin binding and activation of recombinant protease nexin I
Published in The Journal of biological chemistry (25-11-1991)“…Structural and functional properties of alpha-protease nexin I (alpha-PNI) expressed in Chinese hamster ovary cells were studied. All three cysteines were in…”
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6
hNT neurons express an immunosuppressive protein that blocks T-lymphocyte proliferation and interleukin-2 production
Published in Journal of neuroimmunology (01-04-2002)“…Ntera2/D1 cells had an A1 B8 Bw6 Cw7 DR3 DR52 major histocompatibility complex (MHC) genotype. Its neuronal derivative, hNT neurons, expressed A1 B8 Bw6 MHC…”
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Molecular Cloning, Characterization, and Expression of a Human 14-kDa Lectin
Published in The Journal of biological chemistry (15-01-1989)“…Full length cDNAs coding for a 14-kDa β-galactoside binding lectin have been isolated from HL-60 cells and human placenta. Oligonucleotide probes based on a…”
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Expression, purification, and characterization of the recombinant proform of eosinophil granule major basic protein
Published in The Journal of immunology (1950) (01-08-1995)“…The cDNA for the highly toxic eosinophil granule major basic protein (MBP) encodes a 25-kDa acidic precursor (proMBP) that is processed to form the 14-kDa…”
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Nucleotide sequence surrounding multiple polyadenylation sites in the mouse dihydrofolate reductase gene
Published in The Journal of biological chemistry (10-05-1982)“…We have previously reported the presence of four dihydrofolate reductase messenger RNAs differing in the length of 3' untranslated regions in murine cells…”
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10
In vitro induction and in vivo expression of bcl-2 in the hNT neurons
Published in Brain research bulletin (15-09-2001)“…Bcl-2 encodes membrane-associated proteins that suppress programmed cell death in cells of various origins. Compelling evidence suggests that bcl-2 is also…”
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Heterogeneity at the 5' termini of mouse dihydrofolate reductase mRNAs. Evidence for multiple promoter regions
Published in The Journal of biological chemistry (25-02-1985)“…We have determined the sequence of the 1000 base pairs of DNA preceding the coding region of the mouse dihydrofolate reductase gene. 700 base pairs upstream of…”
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Isolation of a complementary DNA clone encoding a precursor to human eosinophil major basic protein
Published in The Journal of experimental medicine (01-12-1988)“…A 14-kD protein was purified from human PMNs and its NH2-terminal sequence was determined. Comparison of a portion of the NH2-terminal sequence of this protein…”
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Clonal Human (hNT) Neuron Grafts for Stroke Therapy : Neuropathology in a Patient 27 Months after Implantation
Published in The American journal of pathology (01-04-2002)“…Although grafted cells may be promising therapy for stroke, survival of implanted neural cells in the brains of stroke patients has never been documented…”
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Differentiation-specific effects of LHON mutations introduced into neuronal NT2 cells
Published in Human molecular genetics (15-02-2002)“…Inheritance of one of three primary mutations at positions 11778, 3460 or 14484 of the mitochondrial genome in subunits of Complex I causes Leber's Hereditary…”
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Protease nexin 1 is expressed in the human placenta
Published in Thrombosis and haemostasis (01-02-1993)“…Protease nexin 1 (PN1), a serine protease inhibitor that inactivates thrombin, urokinase, and plasmin, is produced abundantly in cultures of human fibroblasts…”
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The transcription factor Nurr1 in human NT2 cells and hNT neurons
Published in Brain research. Developmental brain research (10-10-2003)“…Human, neuronally committed hNT or NT2-N cells, originally derived from the Ntera2/D1 (NT2) clone after exposure to retinoic acid (RA), represent a potentially…”
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Dopaminergic phenotype of hNT cells in vitro
Published in Brain research. Developmental brain research (30-07-2000)“…We investigated the catecholaminergic nature of cultured hNT neurons previously treated either for 4 or 5 weeks with retinoic acid (RA). There were…”
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Two Regions of the Adenovirus 2 Genome Specify Families of Late Polysomal RNAs Containing Common Sequences
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-1978)“…Late cytoplasmic RNAs specified by two regions of the adenovirus 2 genome (39.3-51.8 and 70.7-83.4 map units) were analyzed by size fractionation of…”
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Nicotinic acetylcholine receptors on NT2 precursor cells and hNT (NT2-N) neurons
Published in Brain research. Developmental brain research (15-11-2002)“…This is the first report, to our knowledge, of prominent, natural expression of nAChR α4, α6 and α9 subunits in a human, neuronally-committed cell line. We…”
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Evaluation of surgical techniques for neuronal cell transplantation used in patients with stroke
Published in Cell transplantation (01-01-2004)“…Transplantation of cultured neuronal cells was performed in two human clinical trials after safety and efficacy was demonstrated in animal models of stroke…”
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